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Associate Professor YOSHIDA Naoko
Faculty, Affiliation
AI Hospital/Macro Signal Dynamics Research and Development Center
Associate Professor
College and School Educational Field
Laboratory
Clinical Pharmacy and Healthcare Sciences
Academic Background
【Academic background(Doctoral/Master's Degree)】
Toyama Medical and Pharmaceutical University Master Graduate School, Division of Pharmaceutical Sciences 200503 Completed
Toyama Medical and Pharmaceutical University Doctor Graduate School, Division of Pharmaceutical Sciences 200803 Completed
【Academic background(Bachelor's Degree)】
Toyama Medical and Pharmaceutical University 200303
【Degree】
Ph.D
Career
Kanazawa University(2009/11/01-)
Hamamatsu University School of Medicine Department of Hospital Pharmacy Pharmacist(2006/11/01-2009/10/31)
Year & Month of Birth
Academic Society
International Pharmaceutical Federation
International Society of Pharmacoepidemiology
Award
○The Pharmaceutical Society of Japan Incentive Award for Women Scientists 2023(2023/03/25)
○The Pharmaceutical Society of Japan Incentive Award for Women Scientists 2023(2023/03/25)
Specialities
Environmental and hygienic pharmacy、Applied pharmacology、Medical sociology、Medical pharmacy
Speciality Keywords
safety evaluation, drug utilization study, pharmacokinetics, Kamopo medicine, falsified medicine
Research Themes
Research on the improvement of the identification of falsified medicines
Safety and security evaluation of personal imported medicines
Investigation of the public health implications of the falsified medicines
Drug safety evaluation and pharmaceutical research for proper use of Kampo medicine
Utilization study and safety evaluation of concomitant drugs in chemotherapy
Books
Papers
- Development of a visual inspection method for identifying falsified medicines obtained by personal import via the Internet. Yoshida N, Maeda S BPB Reports 8 2 27-37 2025/02/26
- Threat of falsifi ed medicines 吉田直子 The Allergy in Practice 44 12 79 2024/10/25
- Threat of falsifi ed medicines 吉田直子 Precision Medicine 7 12 53 2024/10/25
- Circulation of COVID-19-related medicines on Japanese websites during the COVID-19 pandemic and their quality and authenticity Zhu S, Yoshida N, Matsushita R, Rahman MS, Kimura K American Journal of Tropical Medicine & Hygiene 111 5 1097 2024/09/17
- Research on the development of methods for detection of substandard and falsified medicines by clarifying their pharmaceutical characteristics using modern technology Yoshida N Biol Pharm Bull 47 5 878 2024/05/01
- Falsified and problematic methandienone products available online: active pharmaceutical ingredient identification by portable Raman spectrometers and quantification by ultra-high-performance liquid chromatography–Fourier tansform mass spectrometry. Schreiber R, Hori M, Takahashi C, Rahman MS, Nakao A, Zhu S, Zhu F, Yoshida N, Maekawa K, Kimura K AAPS Open 10 5 2024/06/03
- Screening and quantification of undeclared PGF2α analogs in eyelash-enhancing cosmetic serums using LC-MS/MS. Rahmana MS, Yoshida N, Hanafusa M, Matsuo A, Zhu S, Stub Y, Takahashi C, Tsuboi H, Matsushita R, Maekawa K, Kimura K J Pharm Biomed Anal 219 114940 2022/09/20
- Elevated ratio of serum anandamide to arachidonic acid intake in community-dwelling women with high depressive symptoms. Tsuboi H, Matsunaga M, Tsujiguchi H, Kannon T, Hosomichi K, Sato T, Tajima A, Yoshida N, Hara A, Nakamura H Neuro Endocrinol Lett 43 3 145-153 2022/09
- Investigating causes of substandard medicines manufactured and distributed in low- and middle-income countries by visualization of ingredient distribution in tablets using chemical imaging. Journal of Pharmaceutical Machinery and Engineering 31 2 37 2022/03/05
- A comprehensive analysis of selected medicines collected from private drug outlets of Dhaka city, Bangladesh in a simple random survey. Rahman MS, Yoshida N, Tsuboi H, Kamoker JR, Kabir N, Schaefermann S, Akimoto Y, Bhuiyan MA, Reza MS, Kimura K Sci Rep 12 1 234 2022/01/07
- Validation of the Japanese version of the center for epidemiologic studies depression scale—Revised: A preliminary analysis. Tsuboi H, Takakura Y, Tsujiguchi H, Miyagi S, Suzuki K, Nguyen TTT, Pham OK, Nakamura H, Shimizu Y, Kambayashi Y, Yoshida N, Hara A Behav Sci 11 8 107 2021
- Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis. Rahman MS, Yoshida N, Tsuboi H, Ishii Y, Akimoto Y, Kimura K Sci Rep 11 1 12145 2021
- Discrimination of falsified erectile dysfunction medicines by use of an ultra-compact raman scattering spectrometer Sanada T, Yoshida N, Kimura K, Tsuboi H Pharmacy 9 1 3 2020
- Omega-3 Eicosapentaenoic Acid Is Related to Happiness and a Sense of Fulfillment—A Study among Female Nursing Workers Tsuboi H, Sakakibara H, Matsunaga M, Tatsumi A, Yamakawa-Kobayashi K, Yoshida N, Shimoi K Nutrients 12 3462 2020
- Clarification of the internal structure and factors of poor dissolution of substandard roxithromycin tablets by near-infrared chemical imaging Sakuda M, Yoshida N, Koide T, Keila T, Kimura K, Tsuboi H Int J Pharm 120232 2021/01
- Quality and authenticity of metformin tablets circulating on Japanese websites Zhu S, Yoshida N, Tsuboi H, Matsushita R, Kimura K Ther Innov Regul Sci 2021/02
- Patient safety and public health concerns: poor dissolution rate of pioglitazone tablets obtained from China, Myanmar and internet sites Rahman MS, Yoshida N, Tsuboi H, Maeda E, Ibarra AVV, Zin T, Akimoto Y, Tanimoto T, Kimura K BMC Pharmacol Toxicol 22 1 12 2021/03
- Quality assessment of Diflucan® tablets distributed online Sanada T, Ohnishi M, Yoshida N, Kimura K, Tsuboi H Medicine Access @ Point of Care 5 1 2021/03
- Detection method of falsified medicines by using a low-cost Raman scattering spectrometer combined with soft independent modeling of class analogy and partial least squares discriminant analysis Sanada T, Yoshida N, Kimura K, Tsuboi H Biol Pharm Bull 2021/05
- Substandard and Falsified Medicines in Myanmar Sakuda M, Yoshida N, Takaoka T, Sanada T, Rahman MS, Tanimoto T, Zin T, Kimura K, Tsuboi H Pharmacy 8 1 45 2020
- A cross-sectional investigation for verification of globalization of falsified medicines in Cambodia, indicated by tablets of sildenafil citrate Yoshida N, Yuasa M, Sovannarith T, Dararth E, Keila T, Kiet HB, Tanimoto T, Tsuboi H, Kimura K Pharmacy 7 3 111 2019
- A Cross-sectional Investigation of the Quality of Selected Medicines for Non-Communicable Diseases in Private Community Drug Outlets in Cambodia during 2011–2013 Rahman M, Yoshida N, Tsuboi H, Sokchamroeun U, Keila T, Sovannarith T, Kiet HB, Dararth E, Akimoto Y, Tanimoto T, Kimura K Am J Trop Med Hyg 101 5 1018 2019
- Psychological well-being and green tea consumption are associated with lower pentosidine serum levels among elderly female residents in Japan Tsuboi H, Takahashi M, Minamida Y, Yoshida N J Psychosom Res 126 109825 2019
- Falsified tadalafil tablets distributed in Japan via the internet Sanada T, Yoshida N, Matsushita R, Kimura K, Tsuboi H Forensic Sci Int 307 110143 2019
- Falsified vardenafil tablets available online Zhu S, Yoshida N, Kimura K, Matsushita R, Tsuboi H J Pharm Biomed Anal 177 112872 2019
- The Health Consequences of Falsified Medicines: A Study of the Published Literature Rahman MS, Yoshida N, Tsuboi H, Tomizu N, Endo J, Onishi M, Akimoto Y, Kimura K Trop Med Int Health 23 12 1294-1303 2018
- What Do Customers Demand from Drug Stores in Japan? Construct Validity and Factor Structure of a Cross-Sectional Survey Minamida Y, Yoshida N, Nishimaki-Tomizu M, Hanada M, Kimura K, Tsuboi H Pharmacy 6 3 98 2018
- An Investigation into the Quality of Medicines in Yangon, Myanmar Islam MR, Yoshida N, Kimura K, Uwatoko C, Rahman MS, Kumada S, Endo J, Ito K, Tanimoto T, Zin T, Tsuboi H Pharmacy 6 3 96 2018
- Survey to identify substandard and falsified tablets in several Asian countries with pharmacopeial quality control tests and principal component analysis of handheld raman spectroscopy. Kakio T, Nagase H, Takaoka T, Yoshida N, Hirakawa J, Macha S, Hiroshima T, Ikeda Y, Tsuboi H, Kimura K Am J Trop Med Hyg 2018
- Classification and Visualization of Physical and Chemical Properties of Falsified Medicines with Handheld Raman Spectroscopy and X-ray Computed Tomography Kakio T, Yoshida N, Macha S, Moriguchi K, Hiroshima T, Ikeda Y, Tsuboi H, Kimura K Am J Trop Med Hyg 97 3 684-689 2017
- Four-year survey of the quality of antimicrobial medicines in Cambodia Islam MR, Yoshida N, Tsuboi H, Sovannarith T, Dararath E, Kiet HB, Sokchamroeun U, Keila T, Tanimoto T, Kimura K Journal of International Health 32 4 233-242 2017
- Quality of omeprazole purchased via the internet and personally imported into Japan: Comparison with products sampled in other Asian countries. Rahman MS, Yoshida N, Sugiura S, Tsuboi H, Keila T, Kiet HB, Zin T, Tanimoto T, Kimura K Trop Med Int Health 23 3 263-269 2018
- Erroneous formulation of delayed-release omeprazole capsules: alert for importing countries. Rahman MS, Yoshida N, Tsuboi H, Keila T, Sovannarith T, Kiet HB, Dararth E, Zin T, Tanimoto T, Kimura K BMC Pharmacol Toxicol 18 1 31 2017
- Detection of fluoroquinolone-induced tendon disorders using a hospital database. Hori K, Yamakawa K, Yoshida N, Ohnishi K, Kawakami J Pharmacoepidemiol Drug Saf 19 S139-140 2010
- Comparative utilization study on antibacterial agents in hospital settings in Japan Takemura M, Yoshida N, Adachi I, Tsutani K, Kawakami J PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 15 Supplement 1 S169 2006
- Utilization study on Japanese traditional medicines in an academic hospital in Japan Yoshida N, Takemura M, Abe H, Kojima M, Adachi I, Tsutani K, Kawakami J PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 15 Supplement 1 S169 2006
- Effects of packaging and storage conditions on the quality of amoxicillin-clavulanic acid - an analysis of Cambodian samples. Khan MH, Hatanaka K, Sovannarith T, Nivanna N, Casas LC, Yoshida N, Tsuboi H, Tanimoto T, Kimura K BMC Pharmacol Toxicol 14 33 2013
- Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study. Khan MH, Tanimoto T, Nakanishi Y, Yoshida N, Tsuboi H, Kimura K BMJ Open 2 3 2012
- Detection of Fluoroquinolone-Induced Tendon Disorders Using a Hospital Database in Japan. Hori K, Yamakawa K, Yoshida N, Ohnishi K, Kawakami J PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 21 8 886-889 2012
- Perceptions and practices of pharmaceutical wholesalers surrounding counterfeit medicines in a developing country: a baseline survey. Khan MH, Akazawa M, Dararath E, Kiet HB, Sovannarith T, Nivanna N, Yoshida N, Kimura K BMC Health Serv Res 11 306 2011
- Kampo Medicine Database Improves Drug Information Service and Pharmaceutical Care for Inpatients in Department of Japanese Oriental Medicine Takaki A, Yoshida N, Watanabe Y, Nakagawa Y, Kitazawa H, Mimura Y, Adachi I, Kawakami J JAPANESE JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES 33 1 15-22 2007
- Method for the evaluation of the stability and usability after opening packages of orally disintegrating tablets: in case of amlodipine besilate products Hori K, Yoshida N, Okumura T, Okamura Y, Kawakami J YAKUGAKU ZASSHI 130 8 1029-1040 2010
- Public Health Implications of Personal Import of Medicines through Internet Brokers (2): Buying Anti-obesity Agents On-line Kimura K, Honma T, Tanimoto T, Takao C, Okumura J, Yoshida N, Akazawa M THE JOURNAL OF HEALTH CARE AND SOCIETY 21 1 55-67 2011
- Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli Fructus Yoshida N, Takagi A, Kitazawa H, Kawakami J, Adachi I TOXICOLOGY AND APPLIED PHARMACOLOGY 209 2 167-173 2005
- Trends in new drug interactions for pharmaceutical products in Japan Yoshida N, Yamada A, Mimura Y, Kawakami J, Adachi I PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 15 6 421-427 2006
- A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010. Yoshida N, Khan MH, Tabata H, Dararath E, Sovannarith T, Kiet HB, Nivanna N, Akazawa M, Tsuboi H, Tanimoto T, Kimura K BMC pharmacology & toxicology 15 13 2014
- Effects of citronellal, a monoterpenoid in Zanthoxyli Fructus, on the intestinal absorption of digoxin in vitro and in vivo Yoshida N, Takagi A, Kitazawa H, Kawakami J, Adachi I JOURNAL OF PHARMACEUTICAL SCIENCES 95 3 552-560 2006
- Inhibition of P-glycoprotein-mediated transport by terpenoids contained in herbal medicines and natural products Yoshida N, Koizumi M, Adachi I, Kawakami J FOOD AND CHEMICAL TOXICOLOGY 44 12 2033-2039 2006
- Investigation Into the Antinfluenza Agent Oseltamivir Distributed via the Internet in Japan. Takahashi N, Tsuboi H, Yoshida N, Tanimoto T, Khan MH, Kimura K Therapeutic Innovation & Regulatory Science 47 6 699 2013
- Inhibitory effects of terpenoids on multidrug resistance-associated protein 2- and breast cancer resistance protein-mediated transport Yoshida N, Takada T, Yamamura Y, Adachi I, Suzuki H, Kawakami J DRUG METABOLISM AND DISPOSITION 36 7 1206-1211 2008
- Counterfeit medicines in Cambodia—Possible causes Khan MH, Okumura J, Sovannarith T, Nivanna N, Nagai H, Taga M, Yoshida N, Akazawa M, Tanimoto T, Kimura K PHARMACEUTICAL RESEARCH 28 3 484-489 2011
- Study on health hazards through medicines purchased on the Internet: a cross-sectional investigation of the quality of anti-obesity medicines containing crude drugs as active ingredients. Yoshida N, Numano M, Nagasaka Y, Ueda K, Tsuboi H, Tanimoto T, Kimura K BMC Complement Altern Med 15 430 2015
Conference Presentations
- Low-quality medicine discrimination of metformin tablets by Raman scattering analysis(conference：FIP Virtual 2020)(2020/09)
- Discriminant analysis of tablets using an ultra-compact Raman spectrometer(conference：FIP Virtual 2020)(2020/09)
- Development of the method for detecting falsified medicines.(conference：Mini-symposium 2019 “German and Japanese Perspectives on Global Substandard & Falsified Medicines”)(2019/03/28)
- Falsified medicine discrimination of levitra tablets on the internet by non-destructive test analysis.(conference：77th FIP World Congress of Pharmacy and Pharmaceutical Sciences 2017)(2017)
- Discrimination of personally imported falsified Cialis by handy raman scattering analysis and near infrared spectroscopic analysis.(conference：77th FIP World Congress of Pharmacy and Pharmaceutical Sciences 2017)(2017)
- Public health concerns of substandard antidiabetic medicine: Quality estimation of pioglitazone by a cross-sectional survey.(conference：6th FIP Pharmaceutical Sciences World Congress 2017)(2017)
Others
- Investigating Causes of Substandard Medicines Manufactured and Distributed in Low- and Middle-Income Countries by Visualization of Ingredient Distribution in Tablets Using Chemical Imaging Mirai Sakuda, Naoko Yoshida 31 2 37-45 2022/03
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「最新科学技術を駆使した効率的低品質薬・偽造薬の駆逐に関する研究」(2019-2024)
○「国際流通する偽造医薬医品等の実態と対策に関する研究」(2023-2025)
○「医薬品プロファイリングによる偽造医薬品スクリーニング法の開発」(2022-2024)
○「医薬品等のインターネット販売に対する監視手法の研究」(2021-2023)
○「国際流通する偽造医薬医品等の実態と対策に関する研究」(2020-2022)
○「不純物プロファイル分析による偽造医薬品鑑別法の精度向上に関する研究」(2014-2015)
○「美容や脳機能の増強等を目的として個人輸入される医薬品等の実態把握のための研究」(2018-2020)
○「医薬品等の個人輸入における保健衛生上の危害に関する研究」(2010-2010)
○「国際流通する偽造医薬医品等の実態と対策に関する研究」(2017-2019)
○「インターネットを通じて国際流通する医薬品の保健衛生と規制に関する調査研究」(2014-2016)
○「地球規模の模造薬（カウンターフィット薬）蔓延に対する規制と健康影響に関する調査研究」(2011-2013)
○「がん化学療法における併用薬の使用実態調査と相互作用の予測に基づく安全性の確立」(2010-2011)
○「薬物トランスポーターを介した漢方薬・生薬と医薬品との相互作用の予測法の開発」(2007-2007)
○「漢方薬による薬物トランスポーターの誘導作用に起因した相互作用の予測法の確立」(2008-2008)
○「カウンターフィットドラッグのグローバル化とその対策に関する研究」(2010-2012)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Presentation and Debate (Freshman Seminar II)(2022)
○Presentation and Debate(2022)
○Introduction to Pharmacy Practice(2022)
○Introduction to Pharmacy Practice(2022)
○Introduction to Pharmacy Practice(2022)
○Introduction to Pharmacy Practice(2022)
○Introduction to Graduation Research in Pharmacy 2(2022)
○Pharmacy Practice 1(2022)
○Experiments in Pharmaceutical Practice 3(2022)
○Pharmacy Practice 4(2022)
○Pharmacy Practice 3(2022)
○Clinical Pharmacy Practice(2022)
○Clinical Pharmacy Practice(2022)
○Seminar in Drug Therapeutics(2022)
○Pharmacy Practice 3(2022)
○Pharmacy Practice 1(2022)
○Pharmaceutical Laws and Regulations 1(2022)
○Pharmaceutical Laws and Regulations 2(2022)
○Pharmacy Practice 1(2022)
○Pharmacy Practice 3(2022)
○Pharmacy Practice 4(2022)
○Exercise of Therapeutic Drug Monitoring(2022)
○Experiments in Pharmaceutical Practice 3(2022)
○Pharmaceutical Laws and Regulations 1(2022)
○Pharmacy Practice 4(2022)
○Exercise of Therapeutic Drug Monitoring(2022)
○Clinical Pharmacy Practice(2022)
○Seminar in Drug Therapeutics(2022)
○Pharmacy Practice 4(2022)
○Clinical Pharmacy Practice(2022)
○Clinical Pharmacy Practice(2022)
○Pharmaceutical Laws and Regulations 2(2022)
○Exercise of Primary Care(2022)
○Pharmacy Practice 1(2022)
○Pharmacy Practice 3(2022)
○Introduction to Region-studies(2021)
○Clinical Pharmacy Practice(2021)
○Seminar in Drug Therapeutics(2021)
○Pharmacy Practice 1(2021)
○Pharmacy Practice 4(2021)
○Pharmacy Practice 2(2021)
○Exercise of Therapeutic Drug Monitoring(2021)
○Clinical Pharmacy Practice(2021)
○Pharmacy Practice 3(2021)
○Seminar in Pharmaceutical Practice(2021)
○Exercise of Primary Care(2021)
○Experiments in Pharmaceutical Practice 3(2021)
○Pharmacy Practice 4(2020)
○Seminar in Pharmaceutical Practice(2020)
○Experiments in Pharmaceutical Practice 3(2020)
○Pharmacy Practice 1(2020)
○Pharmacy Practice 2(2020)
○Pharmacy Practice 3(2020)
○Clinical Pharmacy Practice(2020)
○Clinical Pharmacy Practice(2020)
○Exercise of Therapeutic Drug Monitoring(2020)
○Exercise of Primary Care(2020)
○Seminar in Drug Therapeutics(2020)
○Pathophysiology(2020)
○Freshman Seminar I(2020)
○Presentation and Debate (Freshman Seminar II)(2020)
○Exercise of Primary Care(2019)
○Seminar in Pharmaceutical Practice(2019)
○Seminar in Drug Therapeutics(2019)
○Seminar in Clinical Pharmacy 1(2019)
○Exercise of Therapeutic Drug Monitoring(2019)
○Hospital Pharmacy Practice 1(2019)
○Seminar in Clinical Pharmacy 2(2019)
○Clinical Pharmacy Practice(2019)
○Experiments in Pharmaceutical Practice 3(2019)
○Pharmacy Practice 2(2019)
○Community Pharmacy Practice 2(2019)
○Pharmacy Practice 1(2019)
○Community Pharmacy Practice 1(2019)
○Pharmacy Practice 3(2019)
○Clinical Pharmacy Practice(2019)
○Seminar in Pharmaceutical Practice(2019)
○Pharmacy Practice 4(2019)
○Seminar in Drug Therapeutics(2019)
○Exercise of Therapeutic Drug Monitoring(2018)
○Experiments in Pharmaceutical Practice 3(2018)
○Seminar in Pharmaceutical Practice(2018)
○Community Pharmacy Practice 1(2018)
○Presentation and Debate (Freshman Seminar II)(2018)
○Hospital Pharmacy Practice 1(2018)
○Exercise of Primary Care(2018)
○Seminar in Drug Therapeutics(2018)
○Community Pharmacy Practice 2(2018)
○Seminar in Clinical Pharmacy 1(2018)
○Clinical Pharmacy Practice(2018)
○Seminar in Clinical Pharmacy 2(2018)
○Hospital Pharmacy Practice 1(2017)
○Community Pharmacy Practice 1(2017)
○Community Pharmacy Practice 2(2017)
○Seminar in Clinical Pharmacy 1(2017)
○Hospital Pharmacy Practice 1(2017)
○Community Pharmacy Practice 2(2017)
○Seminar in Clinical Pharmacy 2(2017)
○Exercise of Therapeutic Drug Monitoring(2017)
○Community Pharmacy Practice 1(2017)
○Experiments in Pharmaceutical Practice 3(2017)
○Seminar in Pharmaceutical Practice(2017)
○Seminar in Drug Therapeutics(2017)
○Seminar in Drug Therapeutics(2012)
○Experiments in Pharmaceutical Practice 3(2012)
○Seminar in Clinical Pharmacy 1(2012)
○Seminar in Clinical Pharmacy 2(2012)
○Seminar in Pharmaceutical Practice(2012)
○Seminar in Drug Therapeutics(2010)