Assistant Professor TAKARADA Mika
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Division of Medicine, Graduate School of Medical Science
Laboratory
TEL:076-265-2162 FAX:076-234-4222
Academic Background
【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor 200903 Completed
Kanazawa University Master 200603 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University 200403
【Degree】
Ph.D (Pharmaceutical Science)
Career
Postdoctoral fellow Kanazawa University, Graduate School of Natural Science and Technology(2009/04/01-2009/07/31)
Assistant Professor Kanazawa University, Graduate School of Medical Sciences(2009/08/01-)
Year & Month of Birth
1982/03
Academic Society
Award
Specialities
Neuroanatomy
Speciality Keywords
Glia, Blood-brain barrier, Brain ischemia, Retina, Unfolded protein response
Research Themes
Regulation of glial activation in CNS injury
Books
Papers
- ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions. Tanaka T, Nguyen DT, Kwankaew N, Sumizono M, Shinoda R, Ishii H, Takarada-Iemata M, Hattori T, Oyadomari S, Kato N, Mori K, Hori O. Neurochem Res. 2023/02/28
- Brain injury triggers cell-type-specific and time-dependent endoplasmic reticulum stress responses. Fan Q, Takarada-Iemata M, Okitani N, Tamatani T, Ishii H, Hattori T, Kiryu-Seo S, Kiyama H, Hori O. Glia 71 3 667-681 2022/11/22
- Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes Roboon J, Hattori T, Nguyen DT, Ishii H, Takarada-Iemata M, Kannon T, Hosomichi K, Maejima T, Saito K, Shinmyo Y, Mieda M, Tajima A, Kawasaki H, Hori O. Front Cell Neurosci. 2022/10/06
- The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity. Nguyen DT, Le TM, Hattori T, Takarada-Iemata M, Ishii H, Roboon J, Tamatani T, Kannon T, Hosomichi K, Tajima A, Taniuchi S, Miyake M, Oyadomari S, Tanaka T, Kato N, Saito S, Mori K, Hori O Scientific Reports 11 1 13086 2021/06/22
- Abnormal social behavior and altered gene expression in mice lacking NDRG2. Takarada-Iemata M, Yoshihara T, Okitani N, Iwata K, Hattori T, Ishii H, Roboon J, Nguyen DT, Fan Q, Tamatani T, Nishiuchi T, Asano M, Hori O. Neurosci Lett. 2020/12/23
- Roles of N-myc downstream-regulated gene 2 in the central nervous system: molecular basis and relevance to pathophysiology. Takarada-Iemata M. Anat Sci Int 96 1 1-12 2020/11/11
- Neurovascular interaction. Takarada-Iemata M, Westenskow PD, Muramatsu R. Neurochem Int. 129 104506 2019/07/16
- Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination. Roboon J, Hattori T, Ishii H, Takarada-Iemata M, Le TM, Shiraishi Y, Ozaki N, Yamamoto Y, Sugawara A, Okamoto H, Higashida H, Kitao Y, Hori O. Front Cell Neurosci. 2019/06/06
- Microglial activation in the cochlear nucleus after early hearing loss in rats Miyako Hatano, Hisashi Sugimoto, Makoto Ito, Masao Noda, Mika Takarada-Iemata, Osamu Hori, Tomohiro Shinozaki, Tomokazu Yoshizaki Auris Nasus Larynx 2019/02/13
- CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously. Hattori T, Kaji M, Ishii H, Jureepon R, Takarada-Iemata M, Ta HM, Le TM, Konno A, Hirai H, Shiraishi Y, Ozaki N, Yamamoto Y, Okamoto H, Yokoyama S, Higashida H, Kitao Y, Hori O. Glia 65 6 974-989 2017/03/13
- Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis. Ta HM, Le TM, Ishii H, Takarada-Iemata M, Hattori T, Hashida K, Yamamoto Y, Mori K, Takahashi R, Kitao Y, Hori O. Journal of Neurochemistry 139 6 1124-1137 2016/07/18
- Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson's Disease. Le TM, Hashida K, Ta HM, Takarada-Iemata M, Kokame K, Kitao Y, Hori O. Parkinsons Disease 2016/02/23
- Deletion of Atf6α enhances kainate-induced neuronal death in mice. Kezuka D, Takarada-Iemata M, Hattori T, Mori K, Takahashi R, Kitao Y, Hori O. Neurochemistry International 92 67-74 2015/12/25
- Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice. Yoshikawa A, Kamide T, Hashida K, Ta HM, Inahata Y, Takarada-Iemata M, Hattori T, Mori K, Takahashi R, Matsuyama T, Hayashi Y, Kitao Y, Hori O. journal of Neurochemistry 132 3 342-353 2015/01/06
- Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury. Takarada-Iemata M, Kezuka D, Takeichi T, Ikawa M, Hattori T, Kitao Y, Hori O. Journal of Neurochemistry 130 3 374-387 2014/04/25
Conference Presentations
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「脳梗塞病態における血管リモデリング機構の解明」(2021-2023)
○「RAGEシグナルを標的とした脳血管障害創薬の為の国際共同研究」(2018-2021)
○「グリア細胞における小胞体ストレス応答を標的とした緑内障病態制御」(2018-2020)
○「網膜神経細胞死に起因するシグナルネットワークにおける小胞体ストレスの重要性」(2015-2016)
○「中枢神経系脱髄疾患におけるアストロサイト特異的遺伝子Ndrg2の重要性」(2015-2016)
○「アストロサイトに発現するNdrg2による血管-神経連関モニタリング」(2012-2013)
○「アストロサイト特異的に発現する分化関連因子Ndrg2の機能解析」(2011-2012)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Neuroanatomy(2018)
○Embryology(2018)
○Human Anatomy(2018)
Classes (Graduate Schools)
○Principles of Anatomy(2018)
○Molecular Targeting in the Central Nervous System(2018)