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Researcher Information

last modified:2020/12/08

Associate Professor YAMASHITA, Satoshi

Faculty, Affiliation

Faculty of Chemistry, Institute of Science and Engineering

College and School Educational Field

Division of Material Chemistry, Graduate School of Natural Science and Technology
Division of Material Chemistry, Graduate School of Natural Science and Technology
Course in Computational Science, School of Mathematics and Physics, College of Science and Engineering

Laboratory

Biological Chemistry lab

Academic Background

【Academic background(Bachelor's Degree)】
Tohoku University Sch. Biochem. Eng.

Career

Tohoku University(2003/04/01-2005/07/31)
National Institutes of Health NIDDK Visiting Fellow(2005/08/01-2010/08)
Kagawa University Research fellow(2010/10/01-2013/03/31)
Tohoku University Dept. Eng. Assistant professor (2013/04/01-2015/11/30)
Kanazawa University Sch. Nat. Sci. Associate professor(2015/12/01-)

Year & Month of Birth

1975/02

Academic Society


Award



Specialities

Applied biochemistry

Speciality Keywords

Natural rubber, isoprenoid, prenyltransferase, Hevea brasiliensis, flavonoid, protein crystallography

Research Themes

Structural and functional characterizations of natural rubber biosynthetic machinery from Hevea brasiliensis

Structural and functional characterizations of natural rubber biosynthetic machinery from Hevea brasiliensis

Structural and functional analyses of biosynthetic enzymes of lipophilic compounds including flavonoids and lignans

Structural and functional analyses of biosynthetic enzymes of lipophilic compounds including flavonoids and lignans

Books

Papers

  •  Molecular mechanisms of natural rubber biosynthesis Yamashita S, Takahashi S Annu. Rev. Biochem. 89 2020/03/30
  •  A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity. Nat. Commun. 11 2020/02/13
  •  Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis. eLife 2016/10/28
  •  Identification and characterization of a novel bacterial β-glucosidase that is highly specific for the β-1,2-glucosidic linkage of sesaminol triglucoside. Biosci. Biotechnol. Biochem. 82 2018/05/26
  •  Purification and characterization of small and large rubber particles from Hevea brasiliensis. Yamashita S, Mizuno M, Hayashi H, Yamaguchi H, Waki T, Miyagi-Inoue Y, Fushihara K, Nakayama T, Takahashi S Biosci. Biotechnol. Biochem. 82 2017/12/01

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  •  Roles of the indole ring of Trp396 covalently bound with the imidazole ring of His398 coordinated to type I copper in bilirubin oxidase. Kataoka K, Ito T, Okuda Y, Sakai Y, Yamashita S, Sakurai T Biochem. Biophys. Res. Commun. 521 2019/10/31

Conference Presentations

  • Identification and in vitro reconstitution of natural rubber biosynthetic complex from the Para rubber tree(conference:The 13th International Meeting on Biosynthesis, Function and Synthetic Biology of Isoprenoids)(2017/07)
  • Reconstitution of natural rubber biosynthetic enzyme from the Para rubber tree(conference:Baltic conference on Plastics and Rubber)(2018/05)
  • In vitro synthesis of natural rubber and its derivatives by enzymes introduced into rubber particles(conference:12th Annual World Protein & Peptide Conference)(2019/06)

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「反応中間体の構造解析によるマルチ銅オキシダーゼの酸素還元機構の解明と応用」(2018-2020) 
○「ゴマ搾り粕から高効率な有用物質生産を可能にする新規酵素の分子解析と応用」(2015-2017) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Biochemistry II(2017)
○Experiments in Basic Chemistry C(2017)
○Biochemistry II(2016)
○Experiments in Basic Chemistry C(2016)

Classes (Graduate Schools)

○Functions of Proteins(2017)
○Molecular Enzyme Chemistry(2017)
○Seminar in Material Creation(2017)
○Functions of Proteins(2017)
○Functions of Proteins(2017)
○Functions of Proteins(2017)
○Material Creation Chemistry IV(2017)
○Seminar in Material Creation(2017)
○Seminar in Material Creation(2016)
○Molecular Enzyme Chemistry(2016)
○Material Creation Chemistry IV(2016)
○Seminar in Material Creation(2016)
○Functions of Proteins(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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