Associate Professor SHIBAGUCHI Tsubasa
Faculty, Affiliation
Institute of Liberal Arts and Science
College and School Educational Field
Division of Regional Development Studies, Graduate School of Human and Socio-Environmental Studies
Division of Natural System, Graduate School of Natural Science and Technology
Laboratory
TEL:076-264-5946 FAX:
Academic Background
【Academic background(Doctoral/Master's Degree)】
Yamaguchi University Master Graduate School of Education 201003 Completed
Osaka University Doctor Graduate School of Frontier Biosciences 201512 Accomplished credits for doctoral program
【Academic background(Bachelor's Degree)】
Yamaguchi University Department of Exercise and Health Sciences 200803
【Degree】
M.A. (Education)
Ph.D.
Career
Kanazawa University Institute of Liberal Arts and Science Associate Professor(2022/04-)
Kanazawa University Institute of Liberal Arts and Science Assistant Professor(2017/04-2022/03)
Kanazawa University Venture Business Laboratory, Organization of Frontier Science and Innovation Postdoctoral fellow(2016/05-2017/03)
Year & Month of Birth
Academic Society
Japan Society of Exercise and Sports Physiology
Japanese Society of Physicl Fitness and Sports Medicine
American College of Sports Medicine
American Physiological Society
Japanese Society of Physicl Fitness and Sports Medicine
Japan Society of Exercise and Sports Physiology
Japan Society of Physical Education, Health and Sport Sciences
Japan Society of Aerospace and Environmental Medicine
The Molecular Biology Society of Japan
Award
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
The Molecular Biology Society of Japan
Specialities
Sports science、Sports science、Sports science
Speciality Keywords
Muscle hypertrophy, Muscle atrophy, Muscle regeneration, Mitochondria
Research Themes
Elucidation of therapeutic strategies for promoting skeletal muscle regeneration and its molecular mechanisms
Attempt to enhance mitochondrial adaptations to exercise in skeletal muscle
Books
- Kazumi Masuda, Tsubasa Shibaguchi Skeletal muscle has the key to healthy life expectancy From molecular basis of systemic regulation through metabolism and endocrine secretion to anti-aging by exercise YODOSHA 2022/01
Papers
- Modulation of mitochondrial dynamics in skeletal muscle during endurance training: early activation of fission and late induction of fusion protein expression Takakura H, Banba H, Yamada T, Koma R, Shibaguchi T, Nonaka Y, and Masuda K J Phys Fitness Sports Med 14 1 2025/01
- Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle Koma R, Shibaguchi T, Yamada T, Nonaka Y, Jue T, Yamazaki A, and Masuda K Acta Physiol (Oxf) e14139 2024/05
- Data on mitochondrial respiratory function in skeletal muscle of adult male mice in response to 3-weeks heat stress Koma R, Matsumoto T, Yamazaki A, Shibaguchi T, Jue T, and Masuda K Data Brief 53 110091 2024/04
- TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes Koma R, Shibaguchi T, Araiso Y, Yamada T, Nonaka Y, Jue T, and Masuda K Physiol Rep 11 7 e15632 2023/04
- Does icing therapy decrease both regenerative and metabolic capacities following skeletal muscle injury? Shibaguchi T, Masuda K, Koma R Descent Sports Science 44 112-119 2023/02
- Effect of daily intake of a rice fermented beverage on endurance exercise performance in male college student athletes Shibaguchi T, Koma R, Riskawati YK, Kawai Y, Yoneda T, Aizaki H, Perez-Lopez C, Tsuji A, Yamazaki Y, Matsui K, and Masuda K J Phys Fitness Sports Med 11 5 279-294 2022/09
- Ryanodine receptors mediate high intracellular Ca(2+) and some myocyte damage following eccentric contractions in rat fast twitch skeletal muscle Tabuchi A, Tanaka Y, Takagi R, Shirakawa H, Shibaguchi T, Sugiura T, Poole DC, and Kano Y Am J Physiol Regul Integr Comp Physiol 322 1 R14-R27 2022/01
- Localization of myoglobin in mitochondria: implication in regulation of mitochondrial respiration in rat skeletal muscle Koma R, Shibaguchi T, Pérez-López C, Oka T, Jue T, Takakura H, and Masuda K Physiol Rep 9 5 e14769 2021/03
- Curcumin induces mitochondrial biogenesis by increasing cAMP levels via PDE4A inhibition in skeletal muscle Hamidie DRR, Shibaguchi T, Yamada T, Koma R, Ishizawa R, Saito Y, Hosoi T, and Masuda K Br J Nutr 126 11 1642-1650 2021/02
- Effect of leucine on microRNAs and mitochondrial biogenesis in C2C12 myotubes Pérez-López C, Shibaguchi T, Morino K, Koma R, and Masuda K Adv Exerc Sports Physiol 26 3 35-42 2020/12
- Impact of different temperature stimuli on the expression of myosin heavy chain isoforms during recovery from bupivacaine-induced muscle injury in rats Shibaguchi T, Hoshi M, Yoshihara T, Naito H, Goto K, Yoshioka T, and Sugiura T J Appl Physiol 127 178-189 2019/05
- Role of astaxanthin supplementation in prevention of disuse muscle atrophy: A review Yoshihara T, Sugiura T, Shibaguchi T, and Naito H J Phys Fitness Sports Med 8 2 61-71 2019/03
- Effect of a combination of astaxanthin supplementation, heat stress, and intermittent reloading on satellite cells during muscle atrophy Yoshihara T, Sugiura T, Miyaji N, Yamamoto Y, Shibaguchi T, Kakigi R, Naito H, Goto K, Ohmori D, Yoshioka T J Zhejiang Univ Sci B 19 844-852 2018
- Age-related changes in myostatin expression in rat skeletal muscle Shibaguchi T, Maeoka T, Yoshihara T, Naito H, Goto K, Yoshioka T, Sugiura T J Phys Fitness Sports Med 2018
- Astaxanthin intake attenuates muscle atrophy caused by immobilization in rats Shibaguchi T, Yamaguchi Y, Miyaji N, Yoshihara T, Naito H, Goto K, Ohmori D, Yoshioka T, Sugiura T Physiol Rep 2016
- Effects of icing or heat stress on the induction of fibrosis and/or regeneration of injured rat soleus muscle Shibaguchi T, Sugiura T, Fujitsu T, Nomura T, Yoshihara T, Naito H, Yoshioka T, Ogura A, Ohira Y J Physiol Sci 2016
- The response of apoptotic and proteolytic systems to repeated heat stress in atrophied rat skeletal muscle Yoshihara T, Sugiura T, Yamamoto Y, Shibaguchi T, Kakigi R, Naito H Physiol Rep 2015
- Phosphorylation of Hsp25 at serine 15 is promoted in immature fibers following in situ muscle contraction Kawano F, Shibaguchi T, Nakai N, Nakata K, Ohira Y J Phys Fitness Sports Med 2015
- Retardation of C2C12 myoblast cell proliferation by exposure to low-temperature atmospheric plasma Nakai N, Fujita R, Kawano F, Takahashi K, Ohira T, Shibaguchi T, Nakata K, Ohira Y J Physiol Sci 2014
- Effects of gravitational loading levels on protein expression related to metabolic and/or morphologic properties of mouse neck muscles Ohira T, Ohira T, Kawano F, Shibaguchi T, Okabe H, Goto K, Ogita F, Sudoh M, Roy RR, Edgerton VR, Cancedda R, Ohira Y Physiol Rep 2014
- Anti-interleukin-6 receptor antibody (MR16-1) promotes muscle regeneration via modulation of gene expressions in infiltrated macrophages Ryo Fujita,Fumimori Kawano,Takashi Ohira,Naoya Nakai,Tsubasa Shibaguchi,Norihiro Nishimoto,Yoshinobu Ohira Biochimica et Biophysica Acta (BBA) - General Subjects 1840 10 3170 2014/10
- The Impact of Long-Term Exposure to Space Environment on Adult Mammalian Organisms: A Study on Mouse Thyroid and Testis Maria Angela Masini,Elisabetta Albi,Cristina Barmo,Tommaso Bonfiglio,Lara Bruni,Laura Canesi,Samuela Cataldi,Francesco Curcio,Marta D'Amora,Ivana Ferri,Katsumasa Goto,Fuminori Kawano,Remo Lazzarini,Elisabetta Loreti,Naoya Nakai,Takashi Ohira,Yoshinobu Ohira,Silvio Palmero,Paola Prato,Franco Ricci,Linda Scarabelli,Tsubasa Shibaguchi,Renza Spelat,Felice Strollo,Francesco Saverio Ambesi-Impiombato PLoS ONE 7 4 e35418 2012/04/25
- Modulation of hippocampal proteins by exposure to simulated microgravity environment during the postnatal development in rats Oke Y,Kawano F,Nomura S,Ohira T,Fujita R,Terada M,Shibaguchi T,Nakai N,Ohira Y Jpn J Aerospace Environ Med 48 3 23 2011
- EFFECTS OF COMBINATION OF HEAT STRESS AND ASTAXANTHIN SUPPLEMENTATION ON DISUSE MUSCLE ATROPHY TOSHINORI YOSHIHARA,TAKAO SUGIURA,TSUBASA SIBAGUCHI,YUKI YAMAMOTO,KATSUMASA GOTO,TOMOMI ISOYAMA,HISASHI NAITO,DAIJIRO OHMORI,TOSHITADA YOSHIOKA Japanese Journal of Physical Fitness and Sports Medicine 59 3 303 2010
- EFFECT OF HEAT STRESS ON DESMIN EXPRESSION IN ATROPHIED SOLEUS MUSCLE TAKAO SUGIURA,TSUBASA SHIBAGUCHI,TOSHINORI YOSHIHARA,YUKI YAMAMOTO,KATSUMASA GOTO,HISASHI NAITO,TOSHITADA YOSHIOKA Japanese Journal of Physical Fitness and Sports Medicine 59 1 167 2010
- Prevention of skeletal muscle atrophy by intermittent reloading with heat stress 芝口翼,杉浦崇夫,古川達也,吉原利典,山元勇樹,後藤勝正,内藤久士,大森大二郎,吉岡利忠 山口県体育学研究 53 53 1 2010
- EFFECT OF LONG-TERM DIETARY ASTAXANTHIN INTAKE ON SARCOPENIA TSUBASA SHIBAGUCHI,TAKAO SUGIURA,TSUKASA FURUMOTO,KOSHIRO INOUE,YOSHIHARU IIDA,TOMOMI ISOYAMA,HISASHI NAITO,KATSUMASA GOTO,DAIJIRO OHMORI,TOSHITADA YOSHIOKA Japanese Journal of Physical Fitness and Sports Medicine 57 5 541 2008
Conference Presentations
- Experience of endurance exercise training augments the hypertrophic effects of exercise in plantaris muscle of re-trained rats(conference：10th FAOPS Congress)(2023/10)
- Effect of endurance exercise on localization of myoglobin in mitochondria in muscle(conference：American College of Sports Medicine (ACSM) 67th Annual Meeting)(2020/05)
- Nutrients stimulate mitochondrial biogenesis via PGC-1α-targeting miRNAs in C2C12 myotubes(conference：American College of Sports Medicine 66th Annual Meeting)(2019/05)
- Negative impact of icing treatment on qualitative recovery of injured Soleus muscle in rats(conference：American College of Sports Medicine 66th Annual Meeting)(2019/05)
Others
- Icing Following Muscle Injury Suppresses Muscle Pain-related Molecules But Exacerbates Fibrosis And Mitochondrial Content Recovery Shibaguchi T 他2名 Med Sci Sports Exerc 55 9S 229-230 2023/09
- Endurance Training Increases Interaction Of Myoglobin With Complex IV In Skeletal Muscle Koma R 他4名 Med Sci Sports Exerc 55 9S 1059 2023/09
- Effects of exercise experience on exercise adaptations during re-training Shibaguchi T 他5名 The Japanese Journal of Physical Fitness and Sports Medicine 72 4 333 2023/08
- Effects of hyperbaric oxygen treatment on post-exercise recovery of glycogen stores in skeletal muscle Nonaka Y 他8名 The Japanese Journal of Physical Fitness and Sports Medicine 72 4 331 2023/08
- Respiratory function of mitochondria isolated from frozen skeletal muslce tissues Koma R 他4名 The Japanese Journal of Physical Fitness and Sports Medicine 72 4 331 2023/08
- Differences of mitochondrial profile in different types of skeletal muscles Nikko T 他5名 The Japanese Journal of Physical Fitness and Sports Medicine 72 4 330-331 2023/08
- Effects of endurance retraining on hypertrophy and mitochondrial adaptation in skeletal muscle Shibaguchi T et al. Journal of Hokuriku Society of Sports Sciences and Physical Education 4 62 2023/03
- Changes in myoglobin content in skeletal muscle mitochondria ater endurance training Koma R et al. Journal of Hokuriku Society of Sports Sciences and Physical Education 4 61 2023/03
- Impact of icing on pain marker and mitochondrial biogenesis following skeletal muscle injury Shibaguchi T et al. J Physical Fitness Sports Med 11 6 336 2022/11
- The effect of TOM complex subunits knockdown on Mb transport into skeletal muscle mitochondria Koma R et al. J Physical Fitness Sports Med 11 6 335 2022/11
- Interaction Of Myoglobin With Hsp70 Chaperone: Implication In Mitochondrial Translocation Via Tom Complex Koma R 他3名 Med Sci Sports Exerc 54 9S 528 2022/09
- Involvement of TOM complex receptor subunits in mitochondrial transport of myoglobin in skeletal muscle Koma R 他3名 The Japanese Journal of Physical Fitness and Sports Medicine 71 4 382-383 2022/08
- Possible transport mechanisms of myoglobin to mitochondria in skeletal muscle Koma R et al. Journal of Hokuriku Society of Sports Sciences and Physical Education 2021/11
- Effects of icing on fibrosis and mitochondrial biogenesis after skeletal muscle injury Shibaguchi T et al. J Physical Fitness Sports Med 10 6 310 2021/11
- Interactions of mitochondrial myoglobin and complex IV in skeletal muscle Koma R et al. J Physical Fitness Sports Med 10 6 311 2021/11
- Effects of icing with or without heat stress on skeletal muscle fibrosis following injury Shibaguchi T 他4名 Med Sci Sports Exerc 53 S109-S110 2021/06
- Submitochondrial Localization Of Myoglobin In Skeletal Muscle Koma R 他4名 Med Sci Sports Exerc 53 S102 2021/06
- Effect of endurance exercise on localization of myoglobin in mitochondria in muscle Koma R 他4名 Med Sci Sports Exerc 52 S154 2020/05
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○「温度刺激が骨格筋再生応答を制御する分子基盤の解明」(2023-2025)
○「骨格筋ミトコンドリアへの非典型的タンパク質輸送の活性化因子とプロテオームの究明」(2023-2025)
○「筋細胞ミトコンドリアの機能修飾をもたらすヘムタンパク質の相互作用」(2021-2024)
○2022「骨格筋ミトコンドリア生合成を促す栄養基質とmicroRNA干渉の解明」(2020-2022)
○2022「骨格筋のミトコンドリアに運動経験を記憶させるための運動条件とその機序の究明」(2020-2022)
○「長期間の重力変化に対するマウス骨格筋の適応メカニズム追究」(2019-2023)
○「骨格筋損傷後のアイシングが線維化を増悪するメカニズムの解明」(2017-2019)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Sports Science(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Sports Science(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Sports Science(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Exercise & Sports Practice(2023)
○Sports Science(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Sports Science(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Sports Science(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2022)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Exercise & Sports Practice(2021)
○Sports Science(2021)
○Sports Science(2021)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Introduction to Date Science(2020)
○Sports Science(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Freshman Seminar I(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Exercise & Sports Practice(2020)
○Presentation and Debate (Freshman Seminar II)(2020)
○Sports Science(2019)
○Sports Science(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Exercise & Sports Practice(2019)
○Sports Science(2018)
○Sports Science(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Exercise & Sports Practice(2018)
○Sports Science(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Sports Science(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Sports and Exercise/Skiing(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Exercise & Sports Practice(2017)
○Sports Science(2017)
○Sports Science(2017)
Classes (Graduate Schools)
○Laboratory Rotation I(2023)
○Laboratory Rotation I(2023)
○Laboratory Rotation Ｉ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory RotationⅠ(2023)
○Laboratory Rotation I(2023)
○Laboratory Rotation I(2023)
○Special Study on Exercise Prescription for Health 2(2023)
○Special Study on Exercise Prescription for Health 1(2023)
○Research Seminar on Exercise and Health Promotion 2(2023)
○Special Study on Sports and Health Sciences 2(2023)
○Research Seminar on Exercise and Health Promotion 1(2023)
○Special Study on Sports and Health Sciences 1(2023)
○Laboratory Rotation II(2023)
○Laboratory Rotation I(2023)
○Laboratory Rotation II(2023)
○Laboratory Rotation I(2023)
○Laboratory RotationⅠ(2023)
○Special Study on Sports and Health Sciences 2(2022)
○Special Study on Sports and Health Sciences 1(2022)
○Special Study on Exercise Prescription for Health 2(2022)
○Special Study on Exercise Prescription for Health 1(2022)
○Research Seminar on Exercise and Health Promotion 2(2022)
○Research Seminar on Exercise and Health Promotion 1(2022)
○Special Study on Exercise Prescription for Health 1(2021)
○Special Study on Exercise Prescription for Health 1(2020)
○Special Study on Exercise Prescription for Health 2(2020)
○Research Seminar on Exercise and Health Promotion 2(2020)
○Research Seminar on Exercise and Health Promotion 2(2020)
○Special Study on Sports and Health Sciences 2(2020)
○Research Seminar on Exercise and Health Promotion 1(2020)
○Special Study on Sports and Health Sciences 1(2020)
○Research Seminar on Exercise and Health Promotion 1(2020)
○Special Study on Exercise Prescription for Health 2(2019)
○Special Study on Exercise Prescription for Health 1(2019)
○Research Seminar on Exercise and Health Promotion 2(2019)
○Research Seminar on Exercise and Health Promotion 1(2019)
○Special Study on Sports and Health Sciences 2(2019)
○Special Study on Sports and Health Sciences 1(2019)
○Research Seminar on Exercise and Health Promotion 2(2019)
○Research Seminar on Exercise and Health Promotion 1(2019)
○Research Seminar on Exercise and Health Promotion 2(2018)
○Research Seminar on Exercise and Health Promotion 1(2018)
○Special Study on Exercise Prescription for Health 2(2018)
○Special Study on Exercise Prescription for Health 1(2018)
○Special Study on Sports and Health Sciences 2(2018)
○Special Study on Sports and Health Sciences 1(2018)
○Lectures in Leading Regional Development Studies(2018)
○Research Seminar on Exercise and Health Promotion 2(2018)
○Research Seminar on Exercise and Health Promotion 1(2018)