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Researcher Information

last modified:2021/04/14

Professor KURACHI, Makoto

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Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Division of Health Sciences,Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of Molecular Genetics, Graduate School of Medicine, Kanazawa University TEL:076-265-2176 FAX:076-234-4225

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Graduate School of Medicine  Internal Medicine 200203 Completed
【Academic background(Bachelor's Degree)】
Kanazawa University 199703
【Degree】
M.D., PhD.

Career

Kanazawa University University Hospital Resident (Internal Medicine)(1997/04-1998/03)
Kurobe City Hospital Resident(1998/04-1999/03)
Kanazawa University University Hospital Medical Staff(1999/04-2000/03)
JST Research staff(2002/04-2004/05)
University of Tokyo Graduate School of Medicine Staff(2004/06-2006/11)
University of Tokyo Graduate School of Medicine Assistant Professor(2006/12-2011/08)
University of Pennsylvania School of Medicine Post doctoral fellow(2011/09-2016/08)
University of Pennsylvania School of Medicine Research Associate(2016/09-2018/08)
Kanazawa University Graduate School of Medicine Professor(2018/09-)

Year & Month of Birth

1973/03

Academic Society

Japanese Society for Immunology

Award

Specialities

Pathological medical chemistry、Immunology、General medical chemistry

Speciality Keywords

Immune response to infection, T lymphocytes, Immunologic memory, Inflammation, Virus infection, cell differentiation, Transcription factor

Research Themes

CD8 T cell differentiation (effector, memory, exhaustion)

Books

Papers

  •  In vivo CD8 + T cell CRISPR screening reveals control by Fli1 in infection and cancer Zeyu Chen, Eri Arai, Omar Khan, Zhen Zhang, Shin Foong Ngiow, Yuan He, Hua Huang, Sasikanth Manne, Zhendong Cao, Amy E Baxter, Zhangying Cai, Elizabeth Freilich, Mohammed A Ali, Josephine R Giles, Jennifer E Wu, Allison R Greenplate, Mohamed A Hakeem, Qingzhou Chen, Makoto Kurachi, Kito Nzingha, Viktoriya Ekshyyan, Divij Mathew, Zhuoyu Wen, Nancy A Speck, Alexis Battle, Shelley L Berger, E John Wherry, Junwei Shi  Cell 184 5 1262 2021/03/04
  •  Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155 Stelekati, E. Chen, Z. Manne, S. Kurachi, M. Ali, M. A. Lewy, K. Cai, Z. Nzingha, K. McLane, L. M. Hope, J. L. Fike, A. J. Katsikis, P. D. Wherry, E. J. Cell Rep 23 7 2142 2018/05/17

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

○Epigenetic modification and cell differentiation by transcription factors

Grant-in-Aid for Scientific Research

○「パイオニア転写因子BATF-IRF4複合体が制御するCTL分化機序の解明」(2019-2021) 
○「肝炎ウイルス特異的T細胞に対する免疫制御機構に関する研究」(2005-2006) 
○「ケモカイン受容体CXCR3によるメモリーCTL樹立・維持の制御機構の解明」(2010-2011) 
○「反復感染応答におけるメモリーCD8陽性T細胞集団の老化と維持機構に関する研究」(2008-2009) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

Classes (Graduate Schools)

International Project

International Students

Lecture themes

Others (Social Activities)

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