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Researcher Information

last modified:2024/03/29

Professor ISHIZAKI Junko

Mail Laboratory Website

Faculty, Affiliation

Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences
Professor

College and School Educational Field

Division of Pharmacy, Graduate School of Medical Science
School of Pharmacy, College of Medical, Pharmaceutical and Health Sciences
School of Pharmaceutical Sciences, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of Clinical Drug Informatics TEL:076-265-2831 FAX:076-234-4212

Academic Background

【Academic background(Bachelor's Degree)】
Kanazawa University 198503

Career

Kanazawa Medical University Department of Geriatric Medicine(1985/04/01-1987/03/31)
Kanazawa University Hospital Pharmacy, School of Medicine(1987/04/01-2005/03/31)
Kanazawa University Graduate School of Natural Science and T(2005/04/01-)

Year & Month of Birth

1963/01

Academic Society







Pharmaceutical Communication Association

Award

Specialities

Clinical Pharmacy Personalized Medicine、Pharmaceutical Care Pharmaceutical Communication、pharmacokinetics therapeutic drug monitoring drug interaction

Speciality Keywords

Clinical Pharmacy Pharmaceutical Care Personalized Medicine Pharmaceutical Care Communication Pharmaceutical Communication pharmacokinetics therapeutic drug monitoring drug interaction

Research Themes

Establishments of evidence-based scientific pharmacotherapy and guideline for extension of healthy life expectancy

Approach to scientific evidence-based drug therapy

Developmento of age-dependent pharmacokinetics

Development of order-made pharmacotherapy

Books

  •  Method of Information Search for Pharmacist 2003/12
  •  Basic manual of clinical pharmacy 2004/04

Papers

  •  Factors associated with medication adherence in Japanese community-dwelling elderly individuals: The Nakajima Study.  N. Ishida, Y. Tokumoto, Y. Suga, M. Shinohara, T. Abe, D. Yuki, A. Mori, M. Horimoto, K. Hayashi, K. Iwasa, M. Yokogawa, M. Ishimiya, H. Nakamura, K. Komai, R. Matsushita, J. Ishizaki , M. Yamada YAKUGAKU ZASSHI 141 1 751-759 2021
  •  A previously unknown drug-drug interaction is suspected in delayed elimination of plasma methotrexate in high-dose methotrexate therapy J. Ishizaki, C. Nakano, K. Kitagawa, Y. Suga, Y. Sai The Annals of Pharmacotherapy  54 1 29-35 2020
  •  Pharmacokinetics and tissue distribution of 3,4-diaminopyridine in rats.  N. Ishida, Y. Kondo, Y. Chikano, E. Kobayashi-Nakade, Y. Suga, J. Ishizaki, K. Komai, R. Matsushita Biopharmaceutics & Drug Disposition 40 294-301 2019
  •  Risk factors for oxaliplatin-induced vascular pain in patients with colorectal cancer and comparison of the efficacy of preventive methods.  Y. Suga, N. Ikeda, M Maeda, A. Y. Staub, T. Shimada, M. Yonezawa, H. Kitade, H. Katsura, M. Okada, J. Ishizaki, Y. Sai, R. Matsushita Journal of Pharmaceutical Health Care and Sciences 2018/04
  •  Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 294 3 1088-1098 2000/03

show all

  •  Binding Disposition of Local Anesthetic Ropivacaine to alpha1-acid Glycoprotein and Interactions with Co-administered Drugs 31 6 445-450 2005/06
  •  Cremophor EL Release Cyclosporine A Adsorbed on Blood Cells and Blood Vessels, and Increases apparent Plasma Consentration of Cyclosporine A INTERNATIONAL JOURNAL OF PHARMACEUTICS 293 137-144 2005/05
  •  Modulation of mdr1a CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone BIOCHEMICAL PHARMACOLOGY 63 777-783 2002
  •  Site-dependent contributions of P-glycoprotein and CYP3A to cyclosporine A absorption, and effect of dexamethasone in small intestine of mice BIOCHEMICAL PHARMACOLOGY 72 1042-1050 2006/06
  •  Involvement of alpha1-acid glycoprotein in inter-individual variation of disposition kinetics of ropivacaine following epidural infusion in off-pump coronary artery bypass grafting K. Yokogawa, S. Shimomura, J. Ishizaki, T. Shimada, C. Fukuwa, M. Kawada, T. Tubokawa, K. Yamamoto, K. Miyamoto JOURNAL OF PHARMACY AND PHARMACOLOGY 59 1 67-73 2007/01
  •  Circadian rhythm of cyctochromeP4502E1 and its effect on disposition kinetics of chlorzoxazonein in rats. P. Khemawoot, K. Nishino, J. Ishizaki, K. Yokogawa, K. Miyamoto EUROPEAN JOURNAL OF PHARMACOLOGY 574 1 71-76 2007/01
  •  Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride. P. Khemawoot, C. Maruyama, H. Tsukada, H. Noda, J. Ishizaki, K. Yokogawa, K. Miyamoto BIOPHARMACEUTICS & DRUG DISPOSITION 28 6 331-338 2007/12
  •  Mechanism of decrease of oral bioavailability of cyclosporine A drug immunotherapy upon coadministration of amphotericin B J. Ishizaki, S. Ito, M. Jin, T. Shimada, T. Ishigaki, Y. Harasawa, K. Yokogawa, A. Takami, S. Nakao, K. Miyamoto BIOPHARMACEUTICS & DRUG DISPOSITION 29 4 195-203 2008/04
  •  Improvement of Clinical Skills through Pharmaceutical Education and Clinical Research Yakugaku-Zasshi 137 1 9-12 2017/01
  •  Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastion, Adriamycin and cisplatin chemotherapy: a retrospective cohort study.  S. Itai, Y. Suga, Y. Hara, K. Izumi, Y. Maeda, Y. Kitagawa, J. Ishizaki, T. Shimada, A. Mizokami, Y. Sai Journal of Pharmaceutical Health Care and Sciences 2017/01
  •  Preventive effects of Salacia reticulate on non-alcoholic fatty liver disease (NAFLD)/ non-alcoholic steatohepatitis (NASH) in monosodium glutamate treated mice. Journal of Traditional Medicines 28 2 73-82 2011/02
  •  Change in pharmacokinetics of mycophenolic acid as a function of age in rats and effect of coadministered amoxicillin/clavulanate BIOLOGICAL & PHARMACEUTICAL BULLETIN 35 7 1009-1013 2012/07
  •  Investigation for Risk Factor and Preventive Effect of NSAIDs, Opioid on Gemcitabine-induced Vascular Pain 38 3 177-183 2012/03
  •  Serum Aminotransferase Activity as a Predictor for Estimation of Total Clearance of Hepatically Metabolized Drugs in Rats with Acute Hepatic Failure K. Yokogawa, A. Ido, T. Kurihara, Y. Mano, M. Nomura, J. Ishizaki, K. Miyamoto Biol. Pharm. Bull. 29 1 141-145 2006/01
  •  Wilms’ Tumor 1 (WT1) Peptide Immunotherapy for Gynecological Malignancy. S. Ohno, S. Kyo, S. Myojo, S. Dohi, J. Ishizaki, K. Miyamoto, S. Morita, J. Sakamoto, T. Enomoto, T. Kimura, Y. Oka, A. Tsuboi, H. Sugiyama, M. Inoue ANTICANCER RESEARCH 29 11 4779-4784 2009/11
  •  Selective drug delivery to bone using acidic oligopeptides.  J. Ishizaki, Y. Waki, T. Takahashi-Nishioka, K. Yokogawa, K. Miyamoto JOURNAL OF BONE AND MINERAL METABOLISM 27 1 1-8 2009/01
  •  Evaluation of Selective Competitive Binding of Basic Drugs to alpha 1-Acid Glycoprotein Variants J. Ishizaki, A. Fukaishi, C. Fukuwa, S. Yamazaki, M. Tabata, T. Ishida, Y. Suga, K. Arai, K. Yokogawa, K. Miyamoto BIOLOGICAL & PHARMACEUTICAL BULLETIN 33 1 95-99 2010/01
  •  Effect of paddle-shaft position and inclination of dissolution apparatus on the dissolution rate of carbamazepine tablets and the equivalence assessment of generic drugs M. Fujimoto, K. Mihara, J. A. Jorgenson, K. Otsuka, M. Aburada, T. Kawada, J. Ishizaki, K. Miyamoto, M. Otsuka Dissolution Technol 17 2 36-45 2010/02
  •  Effect of paddle-shaft position on the dissolution rate of sodium diclofenac tablets and the equivalence assessment of a generic product M. Fujimoto, K. Mihara, J. A. Jorgenson, K. Otsuka, M. Aburada, T. Kawada, J. Ishizaki, K. Miyamoto, M. Otsuka Dissolution Technol 16 4 29-34 2009/04
  •  Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model Y. Matsuo, T. Ishihara, J. Ishizaki, K. Miyamoto, M. Higaki, N. Yamashita Cell Immunol 260 1 33-38 2009/01
  •  Comparison of Relationship between Dosage and Serum Concentration of Voriconazole in Adult and Pediatric Patients Japanese Journal of Pharmaceutical Health Care and Sciences 36 4 213-219 2010/04
  •  Diabetes Mellitus, Elevated Hemoglobin A1c, and Glycated Albumin Are Associated with the Presence of All-Cause Dementia and Alzheimer’s Disease: The JPSC-AD Study.  Journal of Alzheimer's Disease 85 1 235-247 2022
  •  Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study. K. Hayashi, M. Noguchi-Shinohara, T. Sato, K. Hosomichi, T. Kannon, C. Abe, C. Domoto, S. Yuki-Nozaki, A. Mori, M. Horimoto, M. Yokogawa, K. Sakai, K. Iwasa, K. Komai, M. Ishimiya, H. Nakamura, N. Ishida, Y. Suga, J. Ishizaki, A. Ishigami, A. Tajima, M. Yamada 16 11 e0259663 2021/11/11

Conference Presentations

Others

Arts and Fieldwork

Patent

Theme to the desired joint research

Grant-in-Aid for Scientific Research

○「医薬品・医療機器等レギュラトリーサイエンス総合研究事業「治験審査委員会のあるべき方向性に関する研究」」(2008-2008)
○「小児薬物療法適正化を目的とした成長過程における薬物体内動態変動要因の検索」(2009-2011) 
○「成長過程や身体機能の変化に伴う薬物体内動態変動要因の検索」(2012-2016) 

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Principle and Practice of Dispensing Pharmacy(2019)
○Principle and Practice of Dispensing Pharmacy(2019)
○Pharmacy Practice 1(2019)
○Community Pharmacy Practice 1(2019)
○Case Coference in a Variety of Clinical Settings(2019)
○Hospital Pharmacy Practice 1(2019)
○Hospital Pharmacy Practice 2(2019)
○Pharmacy Practice 4(2019)
○Drug Evaluationology(2019)
○Safety Management for Drug Therapy(2019)
○Pharmacy Practice 2(2019)
○Pharmacy Practice 3(2019)
○Community Pharmacy Practice 2(2019)
○Clinical Pharmacy Practice(2019)
○Seminar in Pharmaceutical Practice(2019)
○Seminar in Drug Therapeutics(2019)
○Community Pharmacy Practice 2(2018)
○Hospital Pharmacy Practice 1(2018)
○Hospital Pharmacy Practice 2(2018)
○Community Pharmacy Practice 1(2018)
○Principle and Practice of Dispensing Pharmacy(2018)
○Seminar in Drug Therapeutics(2018)
○Case Coference in a Variety of Clinical Settings(2018)
○Principle and Practice of Dispensing Pharmacy(2017)
○Principle and Practice of Dispensing Pharmacy(2017)
○Community Pharmacy Practice 2(2017)
○Hospital Pharmacy Practice 1(2017)
○Community Pharmacy Practice 1(2017)
○Community Pharmacy Practice 2(2017)
○Community Pharmacy Practice 1(2017)
○Seminar in Drug Therapeutics(2017)
○Seminar in Pharmaceutical Practice(2017)
○Hospital Pharmacy Practice 1(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Hospital Pharmacy Practice 2(2017)
○Principle and Practice of Dispensing Pharmacy(2017)
○Principle and Practice of Dispensing Pharmacy(2017)
○Seminar in Drug Therapeutics(2016)
○Hospital Pharmacy Practice 1(2016)
○Community Pharmacy Practice 2(2016)
○Hospital Pharmacy Practice 2(2016)
○Community Pharmacy Practice 1(2016)
○Principle and Practice of Dispensing Pharmacy(2016)
○Principle and Practice of Dispending Phaymacy(2009)
○Seminar in Drug Therapeutics(2009)
○Principle and Practice of Dispensing Pharmacy(2007)
○Seminar in Clinical Pharmacy(2007)
○Dispensing Pharmacy Practice(2007)
○Dispensing Pharmacy Practice(2006)
○Principle and Practice of Dispensing Pharmacy(2006)
○Seminar in Clinical Pharmacy(2006)

Classes (Graduate Schools)

○Medical Communication(2018)
○Medical Communication(2016)

International Project

International Students

Lecture themes

Others (Social Activities)

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