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Researcher Information

last modified：2025/03/18

Professor　TOKORO Masaharu

Mail Laboratory Website

Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences　Departmet of global infectious diseases

College and School Educational Field

Graduate School of Advanced Preventive Medical Sciences
Division of Medical Sciences, Graduate School of Medical Science
Division of Advanced Preventive Medical Sciences,Graduate School of Advanced Preventive Medical Sciences
Division of Environmental Science, Graduate School of Medical Scienc
School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Department of parasitology　TEL:076-265-2821　FAX:076-234-4242

Academic Background

【Academic background(Doctoral/Master's Degree)】
Keio University　Doctor　Graduate School, Division of Medicine　200103　Accomplished credits for doctoral program
【Academic background(Bachelor's Degree)】
Akita University　199703

Career

(2001/04/01-2003/03/31)
(2001/04/01-2005/03/31)
Kanazawa University　Department of Parasitology,(2003/04/01-2005/03/31)
Kanazawa University　Department of Parasitology(2005/04/01-)

Year & Month of Birth

1964/05

Academic Society


The Japanese Society of Clinical Parasitolgoy

JAPANESE SOCIETY OF TROPICAL MEDICINE

Award

Specialities

Parasitology (including sanitary zoology)

Speciality Keywords

molecular epidemiology,molecular evolution,drug development,tropical medecine,intestinal protozoan parasites,Parasitology

Research Themes

Analysis of intra-species diversity in intestinal protozoan parasites using molecular taxonomy

Reveal the intra-species diversity within the population of each intestinal protozoan parasite from an evolutionary viewpoint to construct a novel prevention approach using selection pressures against the spread of drug-resistant parasites.

Epidemiologic analysis regarding parasitic burdens in endemic areas

To maintain the international co-operational relationships with partners in endemic tropical countries, and to fight against expected pandemics of protozoal infectious diseases, several field works in those areas are ongoing.

Books

Papers

  • 　A case of a head contusion by wound myasis after being lost in the mountains in Okutama, Japan　Clinical parasitolgoy　35　1　53-55　2024/12/01
  • 　A case of acute myeloid leukemia with cutaneous amebiasis due to Entamoeba histolytica　Clinical parasitolgoy　35　1　67-70　2024/12/01
  • 　A case of diarrhea caused by Cryptosporidium hominis in a patient with HIV/AIDS：the importance of rapid tests　Masaharu Tokoro, Fukumi Nakamura-Uchiyama, Tetsushi Mizuno, Naoya Sakamoto, Jun Asuke　Clinical parasitolgoy　35　1　76-79　2024/12/01
  • 　Molecular detection and identification of Enteromonas species in human and animal hosts using polymerase chain reaction and DNA sequencing. 　Lacante SA, Jiang C, Mustamir AA, Mizuno T, Bi X, Syafruddin D, Tokoro M. 　MethodsX　13　102875　2024/07/23
  • 　Infant gastrointestinal canthariasis caused by cigarette beetle (Lasioderma serricorne).　Tetsushi Mizuno,Masaharu Tokoro,Tetsuo Yagi,Etsuko Wada,Ichiro Yamadori,Meiji Arai　Parasitology international　102921　2024/07/05

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  • 　Trends in drug resistance mutations among HIV-1-infected children in Kenya from 2014 to 2018.　Sheila Kageha, Xiuqiong Bi, Quynh T. Nguyen, Raphael Lihana, Dama Olungae, Joyceline G. Kinyua, Rency J. Lel, Joseph Mwangi, Vincent Okoth, Matilda Saina, Son T. Chu, Matilu M. Mwau, Elijah M. Songok, Masaharu Tokoro, Hiroshi Ichimura. 　Preventive Medicine Research　1　5　64-77　2024/03/13
  • 　Molecular screening of Entamoeba spp. (E. histolytica, E. dispar, E. coli, and E. hartmanni) and Giardia intestinalis using PCR and sequencing. 　Tokoro M, Mizuno T, Bi X, Lacante SA, Jiang C, Makunja RN　MethodsX　11　102361.　2023/09/11
  • 　Intestinal parasitic infections and risk factors for infection in Kenyan children with and without HIV infection.　Bridget Ivy Agutu Otieno,Elizabeth Jemaiyo Matey,Xiuqiong Bi,Masaharu Tokoro,Tetsushi Mizuno,Annie Panikulam,Mary Owens,Elijah Maritim Songok,Hiroshi Ichimura　Parasitology international　94　102717　2023/06
  • 　Antibacterial effect and biological reaction of calcium phosphate cement impregnated with iodine for use in bone defects.　Morinaga S, Yamamoto N, Tokoro M, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Taniguchi Y, Asano Y, Nojima T, Tsuchiya H.　J Biomater Appl.　37　10　1716-1723　2023/04/19
  • 　Human case of subcutaneous nodule because of a novel genetic variation of Dirofilaria sp.　Masaharu Nakao,Ai Okamura,Tetsushi Mizuno,Kazuhiko Takehara,Masaharu Tokoro,Takashi Matsushita　The Journal of dermatology　46　10　914　2019/10
  • 　Three monophyletic clusters in Retortamonas species isolated from vertebrates.　Joko Hendarto,Tetsushi Mizuno,Anggi P N Hidayati,Ismail E Rozi,Puji B S Asih,Din Syafruddin,Hisao Yoshikawa,Makoto Matsubayashi,Masaharu Tokoro　Parasitology international　69　93　2019/04
  • 　Possible pathogenicity of commensal Entamoeba hartmanni revealed by molecular screening of healthy school children in Indonesia.　Takahiro Matsumura,Joko Hendarto,Tetsushi Mizuno,Din Syafruddin,Hisao Yoshikawa,Makoto Matsubayashi,Taro Nishimura,Masaharu Tokoro　Tropical medicine and health　47　7　2019
  • 　Molecular characterization of highly pathogenic Eimeria species among beef cattle on Java Island, Indonesia.　Fitrine Ekawasti,Wisnu Nurcahyo,April Hari Wardhana,Tomoyuki Shibahara,Masaharu Tokoro,Kazumi Sasai,Makoto Matsubayashi　Parasitology international　72　doi: 10.1016/j.parint.2019.101　101927　2019/10
  • 　Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model.　Kunitaka Yoshida,Mitsuhiro Iyori,Andrew M Blagborough,Ahmed M Salman,Pawan Dulal,Katarzyna A Sala,Daisuke S Yamamoto,Shahid M Khan,Chris J Janse,Sumi Biswas,Tatsuya Yoshii,Yenni Yusuf,Masaharu Tokoro,Adrian V S Hill,Shigeto Yoshida　Scientific reports　8　1　3896　2018/03/01
  • 　Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model　Kunitaka Yoshida,Mitsuhiro Iyori,Andrew M. Blagborough,Ahmed M. Salman,Pawan Dulal,Katarzyna A. Sala,Daisuke S. Yamamoto,Shahid M. Khan,Chris J. Janse,Sumi Biswas,Tatsuya Yoshii,Yenni Yusuf,Masaharu Tokoro,Adrian V. S. Hill,Shigeto Yoshida　Scientific Reports　8　1　3896　2018/12/01
  • 　Trichomonads detected by microscopic examination of urine sedimentation: high enedemicity of sexually transmitted protozoan infection among elderly population.　Hideaki Hatanaka,Hisaji Arai,Masaharu Tokoro,Joko Hendarto Tukimin,Takehiro Nagamoto,Tetsushi Mizuno　Clinical Parasitology　29　1　24　2018/12
  • 　A case of giardiasis diagnosed by the presence of trophozoites in pancreatic juice　Satoru Kawai,Masaharu Tokoro,Atsuhito Fukushima,Akira Hishinuma,Keiichiro Abe,Hideyuki Hiraishi,Haruka Furumai,Hiromi Machida,Yasuo Imai,Masato Kato,Yuki Sakuraoka,Keiichi Kubota,Yuichi Chigusa　Clinical Parasitology　29　1　33　2018/12
  • 　Molecular phylogeny of Blastocystis isolates from wild rodents captured in Indonesia and Japan.　Maai Katsumata,Hisao Yoshikawa,Masaharu Tokoro,Tetsushi Mizuno,Takehiro Nagamoto,Joko Hendarto,Puji B S Asih,Ismail E Rozi,Isao Kimata,Kazutoshi Takami,Din Syafruddin　Parasitology research　117　9　2841　2018/09
  • 　Histopathologically detected Anisakis pegreffii in gastrectomy tissue of stomach cancer: carcinogenesis or tropism of the parasite?　Masaharu Tokoro,Kenichi Harada,Tetsushi Mizuno　Clinical Parasitology　29　1　80　2018/12
  • 　Etra-gastrointestinal anisakidosis caused by Pseudoterranova azarasi identified by molecular analysis　Tetsushi Mizuno,Takehiro Nagamoto,Masaharu Tokoro,Akari Mitsuboshi,Yusuke Ito,Masaki Kasai　Clinical Parasitology　28　1　28　2017/12
  • 　Extra-gastrointestinal anisakidosis caused by Pseudoterranova azarasi manifesting as strangulated inguinal hernia.　Akari Mitsuboshi,Hiroshi Yamaguchi,Yusuke Ito,Tetsushi Mizuno,Masaharu Tokoro,Masashi Kasai　Parasitology international　66　6　810　2017/12
  • 　An atypical presentation of Trichomonas tenax in liver abscesses associated with gallbladder carcinoma　Masaharu Tokoro,Momi Matsushita,Kyouhei Nishiguchi,Maiko Taniguchi,Akiko Asakura,Manaka Mori,Yosuke Kawasaki,Takaaki Tokuda,Yu Sato,Koji Saiki,Yuki Tokuda,Aya Ishimi,Yoshiki Onishi,Tomoyo Kawai,Mina Hamano,Miho Chiba,Katsumi Yamamoto,Nobuyuki Tatsumi,Atsuko Hiderita,Takehiro Nagamoto　Clinical Parasitology　28　1　90　2017/12
  • 　A case of giardiasis with hypereosinophilia after percutaneous endoscopic gastrostomy　Takahiro Matsumura,Tomoji Yuno,Yasuyuki Nishimura,Masaharu Tokoro　Clincal Parasitology　23　1　86-89.　2012/12
  • 　Assemblage-Dependent Genetic Features of Giardia intestinalis in Humans　Hussein A,Nakamoto K,Arai T,Tokoro M　Palestinian Medical and Pharmaceutical Journal　1　2　49　2016/06/01
  • 　Ancylostoma ceylanicum hookworm infection in Japanese traveler who presented chronic diarrhea after return from Lao People's Democratic Republic.　Daisuke Kaya,Masahide Yoshikawa,Toshiya Nakatani,Fumimasa Tomo-Oka,Yuki Fujimoto,Koji Ishida,Yukihisa Fujinaga,Yosuke Aihara,Shinsaku Nagamatsu,Eijo Matsuo,Masaharu Tokoro,Yukiteru Ouji,Eiryo Kikuchi　Parasitology international　65　6 Pt A　737　2016/12
  • 　Positive correlation of HIV infection with Giardia intestinalis assemblage B but not with assemblage A in asymptomatic Kenyan children.　Elizabeth J Matey,Masaharu Tokoro,Tetsushi Mizuno,Takahiro Matsumura,Takehiro Nagamoto,Xiuqiong Bi,Jane A Oyombra,Willie K Sang,Elijah M Songok,Hiroshi Ichimura　AIDS (London, England)　30　15　2385　2016/09/24
  • 　Lower prevalence of Entamoeba species in children with vertically transmitted HIV infection in Western Kenya.　Elizabeth Jemaiyo Matey,Masaharu Tokoro,Takehiro Nagamoto,Tetsushi Mizuno,Matilda Chelimo Saina,Xiuqiong Bi,Jane A Oyombra,Paul Okumu,Benard Kibet Langat,Willie Kipkemboi Sang,Elijah Maritim Songok,Hiroshi Ichimura　AIDS (London, England)　30　5　803　2016/03/13
  • 　Progressive HIV-associated Cholangiopathy in an HIV Patient Treated with Combination Antiretroviral Therapy　Kazuo Imai,Kazuhisa Misawa,Takahiro Matsumura,Yuji Fujikura,Kei Mikita,Masaharu Tokoro,Takuya Maeda,Akihiko Kawana　INTERNAL MEDICINE　55　19　2881　2016/10
  • 　First report of mixed Entamoeba polecki (ST 1) and E. suis infection in piglets shedding abnormalfeces by histopathological and molecular surveys.　Makoto Matsubayashi,Yuri Sasagawa,Tsunehiko Aita,Masaharu Tokoro,Makoto Haritani,Tomoyuki Shibahara　Acta parasitologica　61　4　665　2016/12/01
  • 　病原微生物別に見た迅速検査：赤痢アメーバ　Kobayashi Seiki,Tokoro Masaharu,Takeuchi Tsutomu　臨床と微生物　27　増刊　732-735　2000/10　
  • 　Purification and identification of major soluble 40-kDa antigenic protein from Entamoeba histolytica: Its application for serodiagnosis of asymptomatic amebiasis　Jun-Ichi Sanuki,Kyoko Nakano,Masaharu Tokoro,Tomoyoshi Nozaki,Eiichi Okuzawa,Seiki Kobayashi,Takashi Asai　Parasitology International　50　2　73　2001
  • 　Evaluation of some pathogens detected from the blood of field rodents in Japan, with special references to geographical distribution and infectivity of Babesia microti　Y.Oikawa,K.Tabara,T.Yoshida,T.Arai,M.Tokoro,N.Takada　49:7-14　2009/10
  • 　Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways.　Tokoro M,Asai T,Kobayashi S,Takeuchi T,Nozaki T　J Biol Chem.　278　43　42717　2003/08
  • 　Sulfur-amino acid biosynthesis in Entamoeba: Characterization of a gene-encoding cystathionine gamma-synthase involved in methionine biosynthesis from Entamoeba　T Nozaki,Y Saito-Nakano,M Tokoro,T Takeuchi　ARCHIVES OF MEDICAL RESEARCH　31　4　S69　2000/07
  • 　Cloning and biochemical characterization of genes encoding two isozymes of cysteine synthase from Entamoeba dispar　T Nozaki,M Tokoro,M Imada,Y Saito,Y Abe,Y Shigeta,T Takeuchi　MOLECULAR AND BIOCHEMICAL PARASITOLOGY　107　1　129　2000/03
  • 　A Case of Giardiasis Expressing Severe Systemic Symptoms and Marked Hypereosinophilia.　Yuhko Suzuki,Takeshi Nakamura,Masaharu Tokoro　Clincal Parasitology　21　1　12　2010/12
  • 　In vitro assessment of anticryptosporidial efficacy and cytotoxicity of adenosine analogues using a SYBR Green real-time PCR method　Tomoko Arai,Isao Kimata,Yukio Kitade,Kentaro Nakamoto,Masaharu Tokoro　JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY　66　3　560　2011/03
  • 　A case of cerebral toxoplasmosis after bonemarrow transplantation　Tomoko Arai,Yukio Kondo,Kohei Hosokawa,Yasunori Sato,Masaharu Tokoro　Clinical Parasitology　21　1　16　2010/12
  • 　Can acquired host immune responses prevent Giardia infection?　Tokoro M,Itoh M,Mizuno T,Rahman MM,Syafruddin D　Recent Advances in Medical Sciences: Parasites and their Human and Animal Hosts　31　2010/10
  • 　Genotyping of Giardia isolates from humans in Japan using the small subunit ribosomal RNA and glutamate dehydrogenase gene sequences　N Abe,Kimata, I,M Tokoro　JAPANESE JOURNAL OF INFECTIOUS DISEASES　58　1　57　2005/02
  • 　Giardia intestinalis Genotyping to Where?　Hussein AIA,Yamaguchia T,Tanaka M,Tokoro M　Parasitic Zoonoses in Asian-Pacific Regions　74　2008/09
  • 　A case of giardiasis expressing severe systemic symptoms and marked hypereosinophilia　Yuhko Suzuki,Takeshi Nakamura,Masaharu Tokoro,Tomiteru Togano,Manabu Ohsaka,Mika Kohri,Yasuyoshi Hirata,Koji Miyazaki,Mikio Danbara,Ryouichi Hone,Ikuo Miura,Keisuke Sunakawa,Masaaki Higashihara　PARASITOLOGY INTERNATIONAL　59　3　487　2010/09
  • 　Two human cases of entamoebiasis: A Brazilian with Entamoeba dispar, Blastocystis hominis and Endolimax nana infection and a Japanese with an asymptomatic ilocecal ulcer with E. histolytica infection　Minoru Yamada,Tatsuya Tegoshi,Mari Tanigawa,Hiroko Yashiro,Masayo Hamahata,Hisao Yoshikawa,Hiroshi Tachibana,Masaharu Tokoro,Eisai Cho　Clincal Parasitology　23　1　82　2012/12
  • 　免疫低下にともなうMAC感染症に合併した呼吸器クリプトスポリジウム症の一例　所 正治,Amjad I. A. Hussein,田中身和,山口智博,森尾友宏,佐藤隆介,水谷修紀　Clinical Parasitology　19　1　55　2008/03
  • 　Bowman's layer encystment in cases of persistent Acanthamoeba keratitis　Hideaki Yokogawa,Akira Kobayashi,Natsuko Yamazaki,Yasuhisa Ishibashi,Yosaburo Oikawa,Masaharu Tokoro,Kazuhisa Sugiyama　Clinical Ophthalmology　6　1　1245　2012/08/01
  • 　Ex vivo laser confocal microscopy findings of cultured Acanthamoeba trophozoites　Natsuko Yamazaki,Akira Kobayashi,Hideaki Yokogawa,Yasuhisa Ishibashi,Yosaburo Oikawa,Masaharu Tokoro,Kazuhisa Sugiyama　Clinical Ophthalmology　6　1　1365　2012/08/21
  • 　ＰＣＲ法による糞便中遺伝子の検出が診断および治療効果の判定に有用であったアメーバ赤痢の1例　95:989-991　5　989　2005/05　
  • 　形態的に赤痢アメーバを検出し得なかったアメーバ性肝膿瘍の2例　所 正治,菱矢直邦,新井正伸,有沢富康,太田雅文,荒山駿介,永元健啓,及川陽三郎　Clinical Parasitology　26　1　96　2015/12/01
  • 　Impact of HIV Infection and Anti-Retroviral Therapy on the Immune Profile of and Microbial Translocation in HIV-Infected Children in Vietnam.　Xiuqiong Bi,Azumi Ishizaki,Lam Van Nguyen,Kazunori Matsuda,Hung Viet Pham,Chung Thi Thu Phan,Kiyohito Ogata,Thuy Thi Thanh Giang,Thuy Thi Bich Phung,Tuyen Thi Nguyen,Masaharu Tokoro,An Nhat Pham,Dung Thi Khanh Khu,Hiroshi Ichimura　International journal of molecular sciences　17　8　pii: E1245　2016/08/02
  • 　確定診断にPCR検査が有用であったアメーバ性肝膿瘍の1例.　馳 亮太,伊藤禎浩,福田和司,所 正治,永元健啓　Clinical Parasitology　27　1　84　2016/12/01
  • 　A case of Clinostomum sp. in Ishikawa prefecture　Y.Oikawa,T.Matsumura,M.Tokoro　Clinical Parasitology　24:109-111　2013/12
  • 　臍帯血および羊水からPCRによってトキソプラズマが検出された先天性トキソプラズマ症例　所 正治,山本 剛,石原温子,坂井理恵　Clinical Parasitology　24　1　27　2013/12/01
  • 　Giardiasis in a patient undergoing chemotherapy for retinoblastoma and acute myelogenous leukemia　Keisuke Otsubo,Hisano Sakaki-Nakatsubo,Hiromichi Taneichi,Keiko Nomura,Toshio Miyawaki,Masaharu Tokoro,Hirokazu Kanegane　PEDIATRICS INTERNATIONAL　55　4　524　2013/08
  • 　First report of multiple-subgenotype mixed infections of Acanthamoeba spp. from clinical isolates of human keratitis cases in Japan　Rahman MM,Tokoro M　Annals of Global Health　80　3　2014/06
  • 　Widespread distribution of Trypanosoma (Herpetosoma) grosi in Japanese field mice (Apodemus speciosus)　Nakamoto K,Tokoro M,Nakamoto T,Saito-Ito A,Oikawa Y,Takada N,Matsumura T,Arayama S,Kamaruddin M　Kanazawa University　13　2　67　2014/12
  • 　Molecular survey of Blastocystis sp. from humans and associated animals in an Indonesian community with poor hygiene.　Hisao Yoshikawa,Masaharu Tokoro,Takehiro Nagamoto,Shunsuke Arayama,Puji B S Asih,Ismail E Rozi,Din Syafruddin　Parasitology international　65　6 Pt B　780　2016/12
  • 　In Vivo Imaging of Radial Keratoneuritis in Patients with Acanthamoeba keratitis by Anterior-Segment Optical Coherence Tomography　Natsuko Yamazaki,Akira Kobayashi,Hideaki Yokogawa,Yasuhisa Ishibashi,Yosaburo Oikawa,Masaharu Tokoro,Kazuhisa Sugiyama　OPHTHALMOLOGY　121　11　2153　2014/11
  • 　In Vivo Laser Confocal Microscopy Findings of Radial Keratoneuritis in Patients with Early Stage Acanthamoeba Keratitis　Akira Kobayashi,Hideaki Yokogawa,Natsuko Yamazaki,Yasuhisa Ishibashi,Yosaburo Oikawa,Masaharu Tokoro,Kazuhisa Sugiyama　OPHTHALMOLOGY　120　7　1348　2013/07
  • 　Genetic identification of Entamoeba polecki subtype 3 from pigs in Japan and characterisation of its pathogenic role in ulcerative colitis.　Makoto Matsubayashi,Naoko Murakoshi,Tetsuya Komatsu,Masaharu Tokoro,Makoto Haritani,Tomoyuki Shibahara　Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases　36　8　2015/12
  • 　First molecular identification of Entamoeba polecki in a piglet in Japan and implications for aggravation of ileitis by coinfection with Lawsonia intracellularis　Makoto Matsubayashi,Kenta Kanamori,Masayuki Sadahiro,Masaharu Tokoro,Niichiro Abe,Makoto Haritani,Tomoyuki Shibahara　PARASITOLOGY RESEARCH　114　8　3069　2015/08
  • 　Molecular Characterization of Various Trichomonad Species Isolated from Humans and Related Mammals in Indonesia　Mudyawati Kamaruddin,Masaharu Tokoro,Md. Moshiur Rahman,Shunsuke Arayama,Anggi P. N. Hidayati,Din Syafruddin,Puji B. S. Asih,Hisao Yoshikawa,Ei Kawahara　KOREAN JOURNAL OF PARASITOLOGY　52　5　471　2014/10
  • 　Split Introns in the Genome of Giardia intestinalis Are Excised by Spliceosome-Mediated trans-Splicing　Ryoma Kamikawa,Yuji Inagaki,Masaharu Tokoro,Andrew J. Roger,Tetsuo Hashimoto　CURRENT BIOLOGY　21　4　311　2011/02
  • 　Genetic Characterization of Clinical Acanthamoeba Isolates from Japan using Nuclear and Mitochondrial Small Subunit Ribosomal RNA　Md Moshiur Rahman,Kenji Yagita,Akira Kobayashi,Yosaburo Oikawa,Amjad I. A. Hussein,Takahiro Matsumura,Masaharu Tokoro　KOREAN JOURNAL OF PARASITOLOGY　51　4　401　2013/08
  • 　A Case of Giardiasis Expressing Severe Systemic Symptoms and Marked Hypereosinophilia.　Yuhko Suzuki, Takeshi Nakamura, Masaharu Tokoro et al.　Clincal Parasitology　21　1　12-15　2010/12
  • 　Ex vivo laser confocal microscopy findings of cultured Acanthamoeba trophozoites.　Yamazaki N,Kobayashi A,Yokogawa H,Ishibashi Y,Oikawa Y,Tokoro M,Sugiyama K　Clin Ophthalmol　6　1365-8　2012/08
  • 　Detection and Identification of Cyclospora cayetanensis by a　Clinical Parasitology　17　1　145-148　2006/03
  • 　New strategy for the development of chemotherapy drugs against Cryptosporidium infection　Arai T,Hussein AIA,Iseki M,Tokoro M　Parasitic Zoonoses in Asian-Pacific Regions　81　2008/09
  • 　Extremely diversified haplotypes observed among assemblage B population of Giardia intestinalis in Kenya.　Tetsushi Mizuno,Elizabeth J Matey,Xiuqiong Bi,Elijah M Songok,Hiroshi Ichimura,Masaharu Tokoro　Parasitology international　75　102038　2020/04
  • 　Antibacterial Activity in Iodine-coated Implants Under Conditions of Iodine Loss: Study in a Rat Model Plus In Vitro Analysis.　Ken Ueoka,Tamon Kabata,Masaharu Tokoro,Yoshitomo Kajino,Daisuke Inoue,Tomoharu Takagi,Takaaki Ohmori,Junya Yoshitani,Takuro Ueno,Yuki Yamamuro,Atsushi Taninaka,Hiroyuki Tsuchiya　Clinical orthopaedics and related research　479　7　1613　2021/07/01
  • 　Combinational therapy with antibiotics and antibiotic-loaded adipose-derived stem cells reduce abscess formation in implant-related infection in rats.　Junya Yoshitani,Tamon Kabata,Hiroshi Arakawa,Yukio Kato,Takayuki Nojima,Katsuhiro Hayashi,Masaharu Tokoro,Naotoshi Sugimoto,Yoshitomo Kajino,Daisuke Inoue,Ken Ueoka,Yuki Yamamuro,Hiroyuki Tsuchiya　Scientific reports　10　1　11182　2020/07/07
  • 　A refractory case of Acanthamoeba keratitis　Tetsushi Mizuno,Kazuki Nakazawa,Hideaki Yokogawa,Akira Kobayashi,Masaharu Tokoro　Clinical Parasitology　30　1　28　2019/12
  • 　An autopsy case of granulomatous amebic encephalitis caused by Balamuthia mandrillaris involving prior amebic dermatitis　Tatsuro Maehara,Tetsushi Mizuno,Masaharu Tokoro,Tatsuru Hara,Yui Tomita,Kouki Makioka,Sei‐Ichiro Motegi,Ayako Yamazaki,Nozomi Matsumura,Sumihito Nobusawa,Hideaki Yokoo　Neuropathology　2022/02/14　
  • 　Longer intervals before vaccination increase spike antibody titers in individuals previously infected with SARS-CoV-2　Xiuqiong Bi,Tomoko Takayama,Masaharu Tokoro,Tetsushi Mizuno,Akinori Hara,Hiroyuki Nakamura,Hiroyasu Oe,Soichiro Nagamatsu,Yoshiki Kitano,Hiroshi Ichimura　Microbiology Spectrum　e0023822　2022
  • 　Molecular diagnoses of ocular parasitic diseases　Masaharu Tokoro　Jounal of the Juzen Medical Society　129　2　26　2020/07
  • 　Molecular identification of Eimeria hestermani and Eimeria prionotemni from a red-necked wallaby (Macropodidae; Macropus rufogriseus) in Japan.　Fitrine Ekawasti,Kazuya Kitagawa,Hiroshi Domae,April Hari Wardhana,Tomoyuki Shibahara,Shigehiko Uni,Masaharu Tokoro,Kazumi Sasai,Makoto Matsubayashi　Parasitology research　119　4　1271　2020/04
  • 　Detections of gastrointestinal parasites, including Giardia intestinalis and Cryptosporidium spp., in cattle of Banten province, Indonesia.　Dyah Haryuningtyas Sawitri,April Hari Wardhana,Eny Martindah,Fitrine Ekawasti,Dias Aprita Dewi,Bambang Ngaji Utomo,Tomoyuki Shibahara,Masahiro Kusumoto,Masaharu Tokoro,Kazumi Sasai,Makoto Matsubayashi　Journal of parasitic diseases : official organ of the Indian Society for Parasitology　44　1　174　2020/03
  • 　A case of giardiasis diagnosed by repeated microscopic stool examinations　Journal of Nara Prefecture General Medical Center　25　1　119　2021/03
  • 　Pathogenicity of Blastocystis spp　Tokoro M,Yoshikawa H　Clinical Parasitology　32　1　15　2021/12
  • 　A case of empyema with ectopic parasitism due to Trichomonas tenax　Hitoomi Okamori,Shigenori Toyota,Seigo Ishii,Toshie Niki,Satoshi Tetsumoto,Masaharu Tokoro,Mayumi Suzuki　Annals of the Japanese Respiratory Society　9　5　374　2020/09
  • 　Prevalence of Enteric Bacteria Pathogens among HIV Infected and Uninfected Children in Dandora, Kenya　Rashid SS,Matey E,Tokoro M,Ichimura H,Nyerere A,Sang W　Journal of Advances in Microbiology　19　1　1　2019/11
  • 　Need for reassessment of “pathogenicity” of commensal intestinal protozoan parasites　Masaharu Tokoro　Clinical Parasitology　32　1　19　2021/12
  • 　Phylogenetic characterization of Isospora jaracimrmani oocysts from a veiled chameleon (family Chamaeleonidae; Chamaeleo calyptratus) reared at a zoo in Ishikawa, Japan　Fitrine EKAWASTI,Kazuya KITAGAWA,Hiroshi DOMAE,April Hari WARDHANA,Junki NAGASAWA,Tomoyuki SHIBAHARA,Masaharu TOKORO,Kazumi SASAI,Makoto MATSUBAYASHI　Journal of Veterinary Medical Science　83　8　1240　2021　
  • 　Occurrence and genetic identifications of porcine Entamoeba, E. suis and E. polecki, at Tangerang in West Java, Indonesia.　April Hari Wardhana,Dyah Haryuningtyas Sawitri,Fitrine Ekawasti,Eny Martindah,Dias Apritadewi,Tomoyuki Shibahara,Masahiro Kusumoto,Masaharu Tokoro,Kazumi Sasai,Makoto Matsubayashi　Parasitology research　119　9　2983　2020/09　

Conference Presentations

  • Human gut intestinal protozoan flora.(conference：The 16th Asian-Pacific congress for Parasitic Zoonoses)(2023/11/26)
  • Inter/intra-species genetic diversities in amebic protozoans: Entamoeba spp. and Acanthamoeba spp.(conference：The 17th Japanese-German Cooperative Symposium on Protozoan Diseases and Workshop of Gastrointestinal Protozoan Diseases)(2011/09/12)
  • Intra-species diversity of intestinal protozoan parasites: How did they evolve into human pathogens?(conference：The 10th Asian-Pacific Congress for Parasitic Zoonoses, Taipei)(2008/08/30)
  • 寄生虫感染症(2014/02/01)
  • インドネシアの辺境地域で人獣から検出される多様な寄生原虫(2015/10/25)

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  • Roles of protozoan flora as a member of the human gut microbiota.(conference：International symposium of the Research Center for Thermotolerant Microbial Resources, Yamaguchi University)(2023/03/10)

Others

  • 　Swine enteritis associated with Entamoeba polecki and Lawsonia intracellular　Kanamori, K,Sadahiro, M,Matsubayashi, M,Tokoro, M,Abe, N,Haritani, M,Shibahara, T　Proceedings of the Japanese Pig Veterinary Society　67　28　2016/02
  • 　Molecular phylogeny of Blastocystis isolates from rodents in the Sumba Island, Indonesia　Katsumata M,Yoshikawa H,Tokoro M,Syafruddin D　Parasitic Zoonoses in Asian-Pacific Regions 2012 (Edited by Tokoro M and Uga S)　29　2012/10
  • 　cARTにより改善したAIDS関連胆管炎の一例　三沢 和央,藤倉 雄二,三木田 馨,前田 卓哉,河野 修一,原 悠,叶 宗一郎,松村 隆弘,所 正治,川名 明彦　日本エイズ学会誌　14　4　377　2012/11

Arts and Fieldwork

Patent

Theme to the desired joint research

○Development of drugs against novel anti-protozoan parasites
○Intra-species diversity of intestinal protozoan parasites

Grant-in-Aid for Scientific Research

○「腸内原虫叢解析のための定量的メタバーコーディングの適用研究」(2022-2024)　
○Festering Joint International Research (B)「Study on the dynamics of initial infections and colonizations with intestinal protozoan parasites」(2019-2024)　
○「視覚的特徴の乏しい物体の検出を可能にする特徴量の探索と原虫類種同定への応用」(2017-2018)　
○「ケニアのHIV感染および非感染小児下痢症における腸管寄生原虫の役割」(2016-2019)　
○「インドネシアの家畜生産性向上に寄与する原虫感染症の実態解明と病態増悪因子の同定」(2016-2018)　
○「途上国における腸管寄生原虫感染実態の網羅的研究」(2014-2016)
○「分子分類を利用した腸管寄生原虫の網羅的検出法の開発」(2013-2015)
○「インドネシアにまん延する病原性腸管寄生原虫の遺伝的多型解析」(2011-2014)　
○「腸管寄生原虫類の網羅的検出法の開発と遺伝子情報リファレンスの構築」(2010-2012)　
○「インドネシアに分布するジアルジアの遺伝的多型形成維持機構の研究」(2008-2010)　
○「クリプトスポリジウム症の効果的な治療に関する研究」(2010-2012)　
○「ジアルジアの種内変異に関する研究：インドネシアの孤立地域での遺伝子型分布」(2006-2007)　

Competitive research funding,Contribution

Collaborative research,Consignment study

Classes (Bachelors)

○Parasitology Research(2024)
○Parasitology(2024)
○Viral Infection(2024)
○Global Health(2024)
○Parasitology Practice(2024)
○Viral Infection Practice(2024)
○Parasitology(2024)
○Parasitology(2024)
○Viral Infection(2024)
○Parasitology(2023)
○Viral Infection(2023)
○Global Health(2023)
○Viral Infection Practice(2023)
○Parasitology Practice(2023)
○Parasitology(2023)
○Parasitology(2023)
○Viral Infection(2023)
○Parasitology(2021)
○Parasitology(2021)
○Parasitology Research(2021)

Classes (Graduate Schools)

○Field work training for parasitology research (Indonesia)(2021)
○Lectures on Protozoal & Helminthic Diseases(2021)
○Introduction to Medical Science(2021)
○Environment and Health -Introductory(2021)
○Training Program for Russia-East Asia Innovative Leaders in Preemptive Medicine(Doctoral Course)(2021)

International Project

International Students

Lecture themes

○Drug developments for neglected diseases
○To fight against endemic diseases

Others (Social Activities)

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