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last modified：2025/04/02
Professor HONDA, Masao
Faculty, Affiliation
Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Division of Health Sciences, Graduate School of Medical Science
Division of Health Sciences，Graduate School of Medical Science
Department of Laboratory Sciences，School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Academic Background
Career
Kanazawa University
Kanazawa University
Kanazawa University
Kanazawa University
Kanazawa University(2007/07/01-)
Year & Month of Birth
Academic Society
Award
Specialities
Gastroenterology、、Immunology、
Speciality Keywords
Liver Disease
Research Themes
Viral Hepatitis
NASH
Hepatokine
Hepatic fibrosis
Molecular biology of HCC
Tumor immunity
Books
- Yamashita T, Honda M, Kaneko S. Cancer Stem Cells - The Cutting Edge InTech 2011
- Yamashita T, Honda M, Kaneko S. Molecular Genetics of Liver Neoplasia Springer 2011
- Honda M, Kaneko S. New Perspectives in Cancer Research and Therapy Research Signpost 2005
- Honda M, Kaneko S. Recent Res. Devel. Experimental Med Tranworld Research Network 2004
- Honda M, Sakai A, Kaneko S, Kobayashi K. Frontiers in Hepatology, Liver cirrhosis Springer-Verlag 2001
- Honda M, Geoff Abell, Kaneko S, Kobayashi K, Stanley M. Lemon. Frontiers in Hepatology, HCV and Related Liver Deseases Springer-Verlag 1999
- 本多政夫, 村居和寿 モデル動物の作製と利用 循環器疾患2021 上巻 エル・アイ・シー 2021/09/09
- 本多政夫, 金子周一. 実験医学増刊 炎症-全体像を知り慢性疾患を制御する 炎症シグナル、免疫細胞のダイナミズムからがん・糖尿病などの発症機序と治療標的まで 羊土社 2014
- 本多政夫, 金子周一. 分子消化器病 特集 消化器疾患におけるsmall RNAの役割を解明する 先端医学社 2015
- 本多政夫, 金子周一. Hepatology Practice 3 C型肝炎の診療を極める 基本から最前線まで 文光堂 2014
- 本多政夫, 金子周一. Hepatology Practice 3 C型肝炎の診療を極める 基本から最前線まで 文光堂 2014
- 本多政夫, 金子周一. Hepatology Practice 4 難治性肝疾患の診療を極める 基本から最前線まで 文光堂 2014
- 本多政夫. Hepatology Practice 1 B型肝炎の診療を極める 文光堂 2013
- 本多政夫, 金子周一. カラー消化器病 基礎と臨床 西村書店 2013
- 本多政夫, 金子周一. 肝疾患 Review 2012-2013 日本メディカルセンター 2012
- 本多政夫, 山下太郎, 上田晃之, 川口和紀, 西野隆平, 鷹取元, 皆川宏貴, 金子周一. DNAチップ活用テクノロジーと応用」 シーエムシー出版 2006
- 本多政夫, 山下太郎, 川口和紀, 金子周一. 肝疾患Review 2006-2007 日本メディカルセンター 2006
- 本多政夫, 山下太郎, 川口和紀, 代田幸博, 金子周一. 消化器疾患最新の治療2005-2006 南江堂 2005
- 本多政夫, 上田晃之, 金子周一. 消化器病学の進歩2005-モノグラフ- 日本消化器病学会 2005
- 本多政夫, 山下太郎, 代田幸博, 金子周一. 先端医療シリーズ25 肝・胆・膵疾患の最新医療 先端医療技術研究所 2003
- 本多政夫, 舘野誠, 山下太郎, 金子周一 C型慢性肝炎治療の新たなストラテジー -インターフェロン治療の今後- 先端医学社 2003
- 本多政夫, 金子周一 メディコピア（39）ウイルス肝炎-最前線 富士レビオ社 1999
- 鍛治恭介, 金子周一, 寺崎修一, 斉藤孝仁, 土山智也, 酒井佳夫, 蓑内慶次, 水腰英四郎, 大野秀棋, 小浦隆義, 酒井明人, 中本安成, 本多政夫, 河合博志, 松下栄紀, 卜部 健, 小林健一. 肝硬変の成因別実態1998 中外医学社 1999
- 本多政夫, 竹内正勇, 稲垣 豊, 金子周一, 鵜浦雅志, 小林健一. 編集 田中 慧, 小原道法. C型肝炎から肝細胞へ メジカルビュウー社 1994
Papers
- Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET. Takayoshi Shirasaki,Satoshi Yamagoe,Tetsuro Shimakami,Kazuhisa Murai,Ryu Imamura,Kiyo-Aki Ishii,Hiroaki Takayama,Yukako Matsumoto,Natsumi Tajima-Shirasaki,Naoto Nagata,Ryogo Shimizu,Souma Yamanaka,Atsushi Abe,Hitoshi Omura,Kazunori Kawaguchi,Hikari Okada,Taro Yamashita,Tomoki Yoshikawa,Kazuhiro Takimoto,Motoko Taharaguchi,Shogo Takatsuka,Yoshitsugu Miyazaki,Toshikatsu Tamai,Yamato Tanabe,Makoto Kurachi,Yasuhiko Yamamoto,Shuichi Kaneko,Kunio Matsumoto,Toshinari Takamura,Masao Honda Nature communications 13 1 3176 2022/06/08
- Induction of selenoprotein P mRNA during hepatitis C virus infection inhibits RIG-I-mediated antiviral immunity. Kazuhisa Murai, Masao Honda, Takayoshi Shirasaki, Tetsuro Shimakami, Hitoshi Omura, Hirofumi Misu, Yuki Kita, Yumie Takeshita, Kiyo-aki Ishii, Toshinari Takamura, Takeshi Urabe, Ryogo Shimizu, Hikari Okada, Taro Yamashita, Yoshio Sakai, Shuichi Kaneko Cell Host & Microbe 25 4 588-601 2019/04/10
- Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid. Qin XY, Suzuki H, Honda M, Okada H, Kaneko S, Inoue I, Ebisui E, Hashimoto K, Carninci P, Kanki K, Tatsukawa H, Ishibashi N, Masaki T, Matsuura T, Kagechika H, Toriguchi K, Hatano E, Shirakami Y, Shiota G, Shimizu M, Moriwaki H, Kojima S. Proc Natl Acad Sci USA 115 19 4969-4974 2018/05/08
- Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle. Misu H, Takayama H, Saito Y, Mita Y, Kikuchi A, Ishii KA, Chikamoto K, Kanamori T, Tajima N, Lan F, Takeshita Y, Honda M, Tanaka M, Kato S, Matsuyama N, Yoshioka Y, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, Kaneko S, Takamura T. Nat Med. 23 4 508-516 2017/04/01
- Malnutrition impairs interferon signaling through mTOR and FoxO pathways in patients with chronic hepatitis C. Honda M, Takehana K, Sakai A, Tagata Y, Shirasaki T, Nishitani S, Muramatsu T, Yamashita T, Nakamoto Y, Mizukoshi E, Sakai Y, Yamashita T, Nakamura M, Shimakami T, Yi M, Lemon SM, Suzuki T, Wakita T, Kaneko S; Hokuriku Liver Study Group. Gastroenterology 141 1 128-40 2011/07/01
- Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C. Honda M, Sakai A, Yamashita T, Nakamoto Y, Mizukoshi E, Sakai Y, Yamashita T, Nakamura M, Shirasaki T, Horimoto K, Tanaka Y, Tokunaga K, Mizokami M, Kaneko S; Hokuriku Liver Study Group Gastroenterology 139 2 499-509 2010/08
- Natural variation in translational activities of the 5 ' nontranslated RNAs of genotypes 1a and 1b hepatitis C virus: Evidence for a long range RNA-RNA interaction outside of the internal ribosomal entry segment M Honda,G Abell,S Kaneko,K Kobayashi,SM Lemon HCV AND RELATED LIVER DISEASES 59 1999
- Detection of the putative E2 protein of hepatitis C virus in human liver Yasunari Nakamoto,Shuichi Kaneko,Masao Honda,Masashi Unoura,Jaehun Cheong,Akihisa Harada,Kouji Matsushima,Kenichi Kobayashi,Seishi Murakami Journal of Medical Virology 42 4 374 1994
- B-Cell epitopes in hypervariable region 1 of hepatitis C virus obtained from patients with chronic persistent hepatitis Yasunari Nakamoto,Shuichi Kaneko,Hideki Ohno,Masao Honda,Masashi Unoura,Seishi Murakami,Kenichi Kobayashi Journal of Medical Virology 50 1 35 1996/09
- A case of hepatitis occuring one year after allogenic bone marrow transplantation; Is it a form of hepatic garft-versus-host disease? Naoki Ikeda,Masashi Unoura,Masao Honda,Mitsuhiro Terada,Eiki Matsushita,Yutaka Inagaki,Shuichi Kaneko,Ken-ichi Kobayashi,Sintarou Shiobara,Tamotsu Matsuda,Akitaka Nonomura,Yasuni Nakanuma Kanzo 31 12 1452 1990
- Risk of hepatitis C virus infections through household contact with chronic carriers: Analysis of nucleotide sequences Masao Honda,Shuichi Kaneko,Masashi Unoura,Kenichi Kobayashi,Seishi Murakami Hepatology 17 6 971 1993/06
- A case of recurrent ischemic colitis associated with barium enema study Masao Honda,Manabu Yonejima,Rieko Saiki,Taisei Sawada,Yoshirou Kitano Nippon Shokakibyo Gakkai Zasshi 89 10 2619 1992
- Sequence comparisons for a hepatitis C virus genome RNA isolated from a patient with liver cirrhosis Masao Honda,Shuichi Kaneko,Masashi Unoura,Kenichi Kobayashi,Seishi Murakami Gene 120 2 317 1992/10
- INVOLVEMENT OF TYPE-II DNA TOPOISOMERASE IN ILLEGITIMATE RECOMBINATION IN ESCHERICHIA-COLI - ANALYSES OF THE PARTIAL DIPLOID OF PHAGE-T4 AND THE SPECIALIZED TRANSDUCING PARTICLES OF PHAGE-LAMBDA H IKEDA,M KUMAGAI,T YAMASHITA,M HONDA MOLECULAR BIOLOGY OF DNA TOPOISOMERASES AND ITS APPLICATION CHEMOTHERAPY 49 1993
- Sequence analysis of putative structural regions of hepatitis C virus isolated from 5 patients Masao Honda Kanzo 32 12 1101 1991
- Degree of diversity of hepatitis C virus quasispecies and progression of liver disease Masao Honda,Shuichi Kaneko,Akito Sakai,Masashi Unoura,Seishi Murakami,Kenichi Kobayashi Hepatology 20 5 1144 1994/11
- Sequence analysis of putative structural regions of hepatitis C virus isolated from 5 Japanese patients with hepatocellular carcinoma M. Honda,S. Kaneko,M. Unoura,K. Kobayashi,S. Murakami Archives of Virology 128 1-2 163 1993/03
- Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon. Shimakami T,Honda M,Kusakawa T,Murata T,Shimotohno K,Kaneko S,Murakami S Journal of virology 80 7 3332 2006/04
- A case of combined hepatocelluar and cholangiocarcinoma in young man ; rapidly progressed and spontaneously ruptured after chemotherapy TAKATORI Hajime,YAMASHITA Tatsuya,KAGAYA Takashi,TSUJI Hirokazu,MIZUKOSHI Eishiro,KAJI Kyousuke,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi Kanzo 44 9 471 2003/09
- Natural variation in translational activities of the 5' nontranslated RNAs of hepatitis C virus genotypes 1a and 1b: Evidence for a long-range RNA- RNA interaction outside of the internal ribosomal entry site Masao Honda,Rene Rijnbrand,Geoff Abell,Desok Kim,Stanley M. Lemon Journal of Virology 73 6 4941 1999
- Hepatic Steatosis and Hepatocellular Carcinoma in Hepatitis C Transgenic Mice Stanley M. Lemon,Herve Lerat,Masao Honda,Kim Loesch,Brian West,Michiari Okuda,Shu-Yuan Xiao,Michael Beard,Yan Yang,Steven A. Weinman Acta Hepatologica Japonica 41 A27 2000
- Genomics research in the liver. 2. Molecule pathogenesis of chronic hepatitis. Honda M,Kaneko S Kanzo 46 10 586 2005/10/25
- Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based comparative genomic hybridization. Kawaguchi K,Honda M,Yamashita T,Shirota Y,Kaneko S Biochemical and biophysical research communications 329 1 370 2005/04
- La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation. Masao Honda,Takeo Shimazaki,Shuichi Kaneko Gastroenterology 128 2 449 2005/02
- Enhanced antitumor effects of a bicistronic adenovirus vector expressing both herpes simplex virus thymidine kinase and monocyte chemoattractant protein-1 against hepatocellular carcinoma Tomoya Tsuchiyama,Shuichi Kaneko,Yasunari Nakamoto,Yoshio Sakai,Masao Honda,Naofumi Mukaida,Kenichi Kobayashi Cancer Gene Therapy 10 4 260 2003/04 ?
- Quasispecies of hepatitis C virus in serum and in three different parts of the liver of patients with chronic hepatitis A Sakai,S Kaneko,M Honda,E Matsushita,K Kobayashi HEPATOLOGY 30 2 556 1999/08
- An infectious molecular clone of a Japanese genotype 1b hepatitis C virus Michael R. Beard,Geoffrey Abell,Masao Honda,Anthony Carroll,Margaret Gartland,Berwyn Clarke,Koyu Suzuki,Robert Lanford,David V. Sangar,Stanley M. Lemon Hepatology 30 1 316 1999
- A case of treatment of advanced hepatocellular carcinoma with hemobilia with a combination therapy consisting of intraarterial chemotherapy and injection of interferon Yoshiko Takata,Tatsuya Yamashita,Akiyoshi Shimatani,Noriho Iida,Kuniaki Arai,Kazuya Kitamura,Takashi Kagaya,Taro Yamashita,Yoshio Sakai,Hirokazu Tsuji,Eishiro Mizukoshi,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko,Tamotsu Koyama Acta Hepatologica Japonica 46 6 365 2005
- [A case of nasal metastasis of hepatocellular carcinoma that was treated under transcatheter arterial embolization for control nasal bleeding]. Komura T,Kagaya T,Tateno M,Arai K,Yamashita T,Yamashita T,Tsuji H,Mizukoshi E,Sakai A,Kaji K,Nakamoto Y,Honda M,Kaneko S,Matsui O Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 102 8 1055 2005/08
- Ephrin-A1 expression contributes to the malignant characteristics of alpha- fetoprotein producing hepatocellular carcinoma H Iida,M Honda,HF Kawai,T Yamashita,Y Shirota,BC Wang,H Miao,S Kaneko GUT 54 6 843 2005/06
- cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation. Honda M,Kawai H,Shirota Y,Yamashita T,Takamura T,Kaneko S Journal of autoimmunity 25 2 133 2005/09
- Pure red cell aplasia associated with concomitant use of mycophenolate mofetil and ribavirin in post-transplant recurrent hepatitis C. Hodo Y,Tsuji K,Mizukoshi E,Yamashita T,Sakai A,Nakamoto Y,Honda M,Kaneko S Transplant international : official journal of the European Society for Organ Transplantation 19 2 170 2006/02
- Approach to establishing a liver targeting gene therapeutic vector using naturally occurring defective hepatitis B viruses devoid of immunogenic T cell epitope Liqun Wang,Shuichi Kaneko,Masao Honda,Kenichi Kobayashi Virus Research 85 2 187 2002/05/10
- Genome-wide transcriptome mapping analysis identifies organ-specific gene expression patterns along human chromosomes T Yamashita,M Honda,H Takatori,R Nishino,N Hoshino,S Kaneko GENOMICS 84 5 867 2004/11
- Cell cycle regulation of hepatitis C virus internal ribosomal entry site-directed translation M Honda,S Kaneko,E Matsushita,K Kobayashi,GA Abell,SM Lemon GASTROENTEROLOGY 118 1 152 2000/01
- Differential gene expression between chronic hepatitis B and C hepatic lesion M Honda,S Kaneko,H Kawai,Y Shirota,K Kobayashi GASTROENTEROLOGY 120 4 955 2001/03
- Genes for systemic vascular complications are differentially expressed in the livers of Type 2 diabetic patients T Takamura,M Sakurai,T Ota,H Ando,M Honda,S Kaneko DIABETOLOGIA 47 4 638 2004/04
- Differential gene expression profiles in stage I primary biliary cirrhosis. Honda M,Kawai H,Shirota Y,Yamashita T,Kaneko S The American journal of gastroenterology 100 9 2019 2005/09
- An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C Kyosuke Kaji,Satoshi Yoshida,Nobuo Nagata,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Yasuhiko Kojima,Shuichi Kaneko Journal of Gastroenterology 39 9 873 2004/09
- Detection of hepatitis B virus DNA in sera from patients with chronic hepatitis B virus infection by DNA microarray method K Kawaguchi,S Kaneko,M Honda,HF Kawai,Y Shirota,K Kobayashi JOURNAL OF CLINICAL MICROBIOLOGY 41 4 1701 2003/04
- Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells M Honda,S Kaneko,T Shimazaki,E Matsushita,K Kobayashi,LH Ping,HC Zhang,SM Lemon HEPATOLOGY 31 6 1351 2000/06
- Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus Hervé Lerat,Masao Honda,Michael R. Beard,Kim Loesch,Jiaren Sun,Yan Yang,Michiari Okuda,Rainer Gosert,Shu-Yuan Xiao,Steven A. Weinman,Stanley M. Lemon Gastroenterology 122 2 352 2002
- A phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap- independent viral translation Masao Honda,Michael R. Beard,Li-Hua Ping,Stanley M. Lemon Journal of Virology 73 2 1165 1999
- Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells LQ Wang,S Kaneko,M Kagaya,H Ohno,M Honda,K Kobayashi JOURNAL OF GASTROENTEROLOGY 37 6 449 2002/06
- alpha-Fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis HF Kawai,S Kaneko,M Honda,Y Shirota,K Kobayashi HEPATOLOGY 33 3 676 2001/03
- Successful Treatment for Autoimmune Hepatitis Complicated with Hepatocellular Carcinoma by Chemotherapy : A report of a case MIZUNO Hideki,YAMASHITA Tatsuya,YAMASHITA Taro,KAGAYA Takashi,MIZUKOSHI Eishiro,TSUJI Hirokazu,KAJI Kyosuke,NAKAMOTO Yasunari,HONDA Masao,KANEKO Syuichi Kanzo 45 2 116 2004/02
- The development and clinical features of splenic aneurysm associated with liver cirrhosis Hajime Sunagozaka,Hirokazu Tsuji,Eishiro Mizukoshi,Kuniaki Arai,Takashi Kagaya,Tatsuya Yamashita,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko Liver International 26 3 291 2006/04
- Genome-wide analysis of gene expression in hepatocellular carcinoma T Yamashita,S Kaneko,M Honda,K Kobayashi STEM CELL AND LIVER REGENERATION 74 2004
- Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays Y Shirota,S Kaneko,M Honda,HF Kawai,K Kobayashi HEPATOLOGY 33 4 832 2001/04
- Inhibition of internal ribosomal entry site-directed translation of HCV by recombinant IFN-alpha correlates with a reduced La protein. Takeo Shimazaki,Masao Honda,Shuichi Kaneko,Kenichi Kobayashi Hepatology (Baltimore, Md.) 35 1 199 2002/01
- Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet Naoto Matsuzawa,Toshinari Takamura,Seiichiro Kurita,Hirofumi Misu,Hitoshi Ando,Masayoshi Yokoyama,Masao Honda,Yoh Zen,Yasuni Nakanuma,Ken-Ichi Miyamoto,Shuichi Kaneko HEPATOLOGY 46 5 1392 2007/11
- A non-Hodgkin lymphoma patient with reactivation of HBV during chemotherapy and emergence of a YMDD-motif mutant on lamivudine, eventually controlled by adfovil dipovoxil TERASHIMA Takeshi,ARAI Kuniaki,KOMURA Takuya,IIDA Hiroshi,KAGAYA Takashi,SAKAI Yoshio,YAMASHITA Tatsuya,SAKAI Akito,MIZUKOSHI Eishiro,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,ZEN You,NAKANUMA Yasuni Kanzo 48 7 309 2007/07/25
- Application of Serial Analysis of Gene Expression in Cancer Research T. Yamashita,M. Honda,S. Kaneko Current Pharmaceutical Biotechnology 9 5 375 2008/10/01
- Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon Nobuhiko Hiraga,Michio Imamura,Masataka Tsuge,Chiemi Noguchi,Shoichi Takahashi,Eiji Iwao,Yoshifumi Fujimoto,Hiromi Abe,Toshiro Maekawa,Hidenori Ochi,Chise Tateno,Katsutoshi Yoshizato,Akihito Sakai,Yoshio Sakai,Masao Honda,Shuichi Kaneko,Takaji Wakita,Kazuaki Chayama FEBS LETTERS 581 10 1983 2007/05
- A case of primary biliary cirrhosis with progressive jaundice due to Basedow's disease SHIMAKAMI Tetsuro,YAMASHITA Tatsuya,SAKAI Yoshio,ARAI Kuniaki,IIDA Hiroshi,KITAMURA Kazuya,KAGAYA Takashi,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi Kanzo 48 9 452 2007/09/25
- Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells. Oishi N,Shilagardi K,Nakamoto Y,Honda M,Kaneko S,Murakami S Cancer science 98 10 1540 2007/10
- Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma Eishiro Mizukoshi,Masao Honda,Kuniaki Arai,Tatsuya Yamashita,Yasunari Nakamoto,Shuichi Kaneko JOURNAL OF HEPATOLOGY 49 6 946 2008/12
- A case of congenital absence of portal vein with focal nodular hyperplasia (FNH) and multiple FNH-like lesions in the liver SHIGEYAMA Isamu,YAMASHITA Tatsuya,ARAI Kuniaki,IIDA Hiroshi,KAKINOKI Kaheita,KAWAGUCHI Kazunori,KITAMURA Kazuya,KAGAYA Takashi,SAKAI Yoshio,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,MATSUI Osamu,NAKANUMA Yasuni Kanzo 48 3 102 2007/03/25
- Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes Toshinari Takamura,Masao Honda,Yoshio Sakai,Hitoshi Ando,Akiko Shimizu,Tsuguhito Ota,Masaru Sakurai,Hirofumi Misu,Seiichiro Kurita,Naoto Matsuzawa-Nagata,Masahiro Uchikata,Seiji Nakamura,Ryo Matoba,Motohiko Tanino,Ken-ichi Matsubara,Shuichi Kaneko BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 361 2 379 2007/09
- A case of portopulmonary hypertension successfully treated by balloon-occluded retrograde transvenous obliteration and home oxygen therapy YAMAMOTO Kanako,KAWAGUCHI Kazunori,KAKINOKI Kaheita,KITAMURA Kazuya,ARAI Kuniaki,IIDA Hiroshi,KAGAYA Takashi,SAKAI Yoshio,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,HONDA Masao,NAKAMOTO Yasunari,TAKAMURA Masayuki,MATSUI Osamu,KANEKO Shuichi Kanzo 48 7 322 2007/07/25
- Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis Takuya Komura,Eishiro Mizukoshi,Yuki Kita,Masaru Sakurai,Yoshiko Takata,Kuniaki Arai,Tatsuya Yamashita,Tetsuo Ohta,Koichi Shimizu,Yasunari Nakamoto,Masao Honda,Toshinari Takamura,Shuichi Kaneko AMERICAN JOURNAL OF GASTROENTEROLOGY 102 9 1939 2007/09
- [Unresectable pancreatic cancer in the Hokuriku area]. Terashima T,Yamashita T,Arai K,Iida H,Kakinoki K,Kitamura K,Kagaya T,Sakai Y,Mizukosi E,Sakai A,Nakamoto Y,Honda M,Kaneko S Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 105 3 373 2008/03
- Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning. Reiji Teramoto,Hirotaka Minagawa,Masao Honda,Kenji Miyazaki,Yo Tabuse,Ken'ichi Kamijo,Teruyuki Ueda,Shuichi Kaneko Biochimica et biophysica acta 1784 5 764 2008/05
- Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity Naoto Matsuzawa-Nagata,Toshinari Takamura,Hitoshi Ando,Seiji Nakamura,Seiichiro Kurita,Hirofumi Misu,Tsuguhito Ota,Masayoshi Yokoyama,Masao Honda,Ken-ichi Miyamoto,Shuichi Kaneko METABOLISM-CLINICAL AND EXPERIMENTAL 57 8 1071 2008/08
- Detection of network structure changes by graphical chain modeling: A case study of hepatitis C virus-related hepatocellular carcinoma Shigeru Saito,Masao Honda,Shu-Ichi Kaneko,Katsuhisa Horimoto Proceedings of the IEEE Conference on Decision and Control 5624 2009
- A case of metastatic gallbladder tumor of the hepatocellular carcinoma TERASHIMA Takeshi,YAMASHITA Tatsuya,ARAI Kuniaki,KAKINOKI Kaheita,KAGAYA Takashi,SAKAI Yoshio,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,OJIMA Toshihiko,KITAGAWA Hirohisa,KAYAHARA Masato,OOTA Tetsuo,ZEN You,NAKANUMA Yasuni Kanzo 48 8 363 2007/08/25
- Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy Makoto Tateno,Masao Honda,Takashi Kawamura,Hiroyuki Honda,Shuichi Kaneko JOURNAL OF INFECTIOUS DISEASES 195 2 255 2007/01
- Detection of network structure changes by graphical chain modeling: a case study of hepatitis C virus-related hepatocellular carcinoma Shigeru Saito,Masao Honda,Shu-ichi Kaneko,Katsuhisa Horimoto PROCEEDINGS OF THE 48TH IEEE CONFERENCE ON DECISION AND CONTROL, 2009 HELD JOINTLY WITH THE 2009 28TH CHINESE CONTROL CONFERENCE (CDC/CCC 2009) 5624 2009
- Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical gaussian model Sachiyo Aburatani,Fuyan Sun,Shigeru Saito,Masao Honda,Shu-Ichi Kaneko,Katsuhisa Horimoto Eurasip Journal on Bioinformatics and Systems Biology 2007 2007
- Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C Masao Honda,Taro Yamashita,Teruyuki Ueda,Hajime Takatori,Ryuhei Nishino,Shuichi Kaneko HEPATOLOGY 44 5 1122 2006/11
- Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma. Nishino R,Honda M,Yamashita T,Takatori H,Minato H,Zen Y,Sasaki M,Takamura H,Horimoto K,Ohta T,Nakanuma Y,Kaneko S Journal of hepatology 49 2 207 2008/08
- Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study Tatsuya Yamashita,Kuniaki Arai,Akito Sakai,Eishiro Mizukoshi,Yoshio Sakai,Takashi Kagaya,Yasunari Nakamoto,Masao Honda,Takashi Wada,Hitoshi Yokoyama,Shuichi Kaneko Hepatology Research 36 3 167 2006/11
- EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Yamashita T,Ji J,Budhu A,Forgues M,Yang W,Wang HY,Jia H,Ye Q,Qin LX,Wauthier E,Reid LM,Minato H,Honda M,Kaneko S,Tang ZY,Wang XW Gastroenterology 136 3 1012 2009/03
- Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients. Sakai Y,Honda M,Fujinaga H,Tatsumi I,Mizukoshi E,Nakamoto Y,Kaneko S Cancer research 68 24 10267 2008/12
- Comparative analysis of proteome and transcriptome in human hepatocellular carcinoma using 2D-DIGE and SAGE. Minagawa H,Yamashita T,Honda M,Tabuse Y,Kamijo K,Tsugita A,Kaneko S The protein journal 27 7-8 409 2008/12
- Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma. Minagawa H,Honda M,Miyazaki K,Tabuse Y,Teramoto R,Yamashita T,Nishino R,Takatori H,Ueda T,Kamijo K,Kaneko S Biochemical and biophysical research communications 366 1 186 2008/02
- Comprehensive gene expression analysis in hepatocellular carcinoma (HCC) by newly developed 5 '-end sage method and identification of novel up-regulated intronic transcript Hodo Yuji,Hashimoto Shin-ichi,Deshimaru Shungo,Honda Masao,Yamashita Taro,Ueda Teruyuki,Matsushima Kouji,Kaneko Shuichi HEPATOLOGY 46 4 798A 2007/10
- Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma. Yamashita T,Honda M,Takatori H,Nishino R,Minato H,Takamura H,Ohta T,Kaneko S Journal of hepatology 50 1 100 2009/01
- A case of refractory hepatic hydrothorax complicated with spontaneous bacterial empyema in a type C liver cirrhosis patient, successfully treated with transjugular intrahepatic portosystemic shunt SHUGO Haruhiko,KAGAYA Takashi,OISHI Naoki,ARAI Kuniaki,KITAMURA Kazuya,SAKAI Yoshio,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi,MATSUI Osamu Kanzo 48 9 439 2007/09/25
- Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes H. Misu,T. Takamura,N. Matsuzawa,A. Shimizu,T. Ota,M. Sakurai,H. Ando,K. Arai,T. Yamashita,M. Honda,T. Yamashita,S. Kaneko DIABETOLOGIA 50 2 268 2007/02
- Panel discussion: HCV infection and host factor, IL28B in particular Yasuhito Tanaka,Katsushi Tokunaga,Masao Honda,Norio Akuta,Yasuhiro Asahina,Masashi Mizokami Acta Hepatologica Japonica 51 7 327 2010/09/01
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- Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection. Taro Yamashita,Masao Honda,Shuichi Kaneko Journal of gastroenterology and hepatology 26 6 960 2011/06
- Pre-treatment prediction of response to pegylated-Interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors. Kurosaki M,Tanaka Y,Nishida N,Sugiyama M,Matsuura K,Asahina Y,Sugauchi F,Sakamoto N,Nakagawa M,Watanabe M,Sakai A,Honda M,Kaneko S,Ito K,Masaki N,Tokunaga K,Izumi N,Mizokami M J Hepatol 54:439-448, 2011 3 439 2011
- La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication. Shirasaki T,Honda M,Mizuno H,Shimakami T,Okada H,Sakai Y,Murakami S,Wakita T,Kaneko S The Journal of infectious diseases 202 1 75 2010/07
- MUCOSAL FINDINGS OF THE SMALL INTESTINE IN PATIENTS WITH PORTAL HYPERTENSION DUE TO LIVER CIRROSIS : A CAPSULE ENDOSCOPY STUDY MIZUNO Hideki,KAGAYA Takashi,OOISHI Naoki,TAKATORI Hajime,YAMASHITA Tatsuya,MIZUKOSHI Eishiro,SAKAI Akito,NAKAMOTO Yasunari,HONDA Masao,KANEKO Shuichi Gastroenterological Endoscopy 53 6 1600 2011/06/20
- Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C. Masao Honda,Mikiko Nakamura,Makoto Tateno,Akito Sakai,Tetsuro Shimakami,Takayoshi Shirasaki,Tatsuya Yamashita,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko Journal of hepatology 53 5 817 2010/11
- Heterogeneity of Liver Cancer Stem Cells Taro Yamashita,Masao Honda,Shuichi Kaneko Molecular Genetics of Liver Neoplasia 301 2010
- Altered hepatic gene expression profiles associated with myocardial ischemia. Ootsuji H,Honda M,Kaneko S,Usui S,Okajima M,Okada H,Sakai Y,Takamura T,Horimoto K,Takamura M Circulation. Cardiovascular genetics 3 1 68 2010/02
- Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C. Tanaka Y,Kurosaki M,Nishida N,Sugiyama M,Matsuura K,Sakamoto N,Enomoto N,Yatsuhashi H,Nishiguchi S,Hino K,Hige S,Itoh Y,Tanaka E,Mochida S,Honda M,Hiasa Y,Koike A,Sugauchi F,Kaneko S,Izumi N,Tokunaga K,Mizokami M Human molecular genetics 20 17 3507 2011/09
- Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C Masao Honda,Akito Sakai,Tatsuya Yamashita,Yasunari Nakamoto,Eishiro Mizukoshi,Yoshio Sakai,Taro Yamashita,Mikiko Nakamura,Takayoshi Shirasaki,Katsuhisa Horimoto,Yasuhito Tanaka,Katsushi Tokunaga,Masashi Mizokami,Shuichi Kaneko GASTROENTEROLOGY 139 2 499 2010/08
- Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. Nishida N,Sawai H,Matsuura K,Sugiyama M,Ahn SH,Park JY,Hige S,Kang JH,Suzuki K,Kurosaki M,Asahina Y,Mochida S,Watanabe M,Tanaka E,Honda M,Kaneko S,Orito E,Itoh Y,Mita E,Tamori A,Murawaki Y,Hiasa Y,Sakaida I,Korenaga M,Hino K,Ide T,Kawashima M,Mawatari Y,Sageshima M,Ogasawara Y,Koike A,Izumi N,Han KH,Tanaka Y,Tokunaga K,Mizokami M PloS one 7 6 e39175 2012
- ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C. Sakamoto N,Tanaka Y,Nakagawa M,Yatsuhashi H,Nishiguchi S,Enomoto N,Azuma S,Nishimura-Sakurai Y,Kakinuma S,Nishida N,Tokunaga K,Honda M,Ito K,Mizokami M,Watanabe M Hepatology research : the official journal of the Japan Society of Hepatology 40 11 1063 2010/11
- CD14(+) Monocytes Are Vulnerable and Functionally Impaired Under Endoplasmic Reticulum Stress in Patients With Type 2 Diabetes Takuya Komura,Yoshio Sakai,Masao Honda,Toshinari Takamura,Kouji Matsushima,Shuichi Kaneko DIABETES 59 3 634 2010/03
- A case report of S-1 monotherapy for advanced hepatocellular carcinoma Tatsuya Yamashita,Kuniaki Arai,Takeshi Terashima,Hajime Sunagozaka,Tetsuro Shimakami,Taro Yamashita,Eishiro Mizukoshi,Akito Sakai,Masao Honda,Shuichi Kaneko Japanese Journal of Cancer and Chemotherapy 39 9 1435 2012
- [Two cases of a nonfunctioning pancreatic endocrine tumor found on a medical checkup]. Nio K,Shimakami T,Yamashita T,Kagaya T,Sakai Y,Yamashita T,Mizukoshi E,Sakai A,Nakamoto Y,Honda M,Kaneko S,Kitagawa H,Kayahara M,Ohta T,Zen Y Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 106 4 560 2009/04
- Differential gene expression profiling in blood from patients with digestive system cancers. Honda M,Sakai Y,Yamashita T,Yamashita T,Sakai A,Mizukoshi E,Nakamoto Y,Tatsumi I,Miyazaki Y,Tanno H,Kaneko S,Hokuriku Liver,Study Group Biochemical and biophysical research communications 400 1 7 2010/09
- Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. Yamashita T,Honda M,Nio K,Nakamoto Y,Yamashita T,Takamura H,Tani T,Zen Y,Kaneko S Cancer research 70 11 4687 2010/06
- Randomized, phase II study comparing interferon combined with hepatic arterial infusion of fluorouracil plus cisplatin and fluorouracil alone in patients with advanced hepatocellular carcinoma. Tatsuya Yamashita,Kuniaki Arai,Hajime Sunagozaka,Teruyuki Ueda,Takeshi Terashima,Taro Yamashita,Eishiro Mizukoshi,Akito Sakai,Yasunari Nakamoto,Masao Honda,Shuichi Kaneko Oncology 81 5-6 281 2011
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- Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma. Eishiro Mizukoshi,Yasunari Nakamoto,Kuniaki Arai,Tatsuya Yamashita,Akito Sakai,Yoshio Sakai,Takashi Kagaya,Taro Yamashita,Masao Honda,Shuichi Kaneko Hepatology (Baltimore, Md.) 53 4 1206 2011/04
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- Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma Hajime Sunagozaka,Masao Honda,Taro Yamashita,Ryuhei Nishino,Hajime Takatori,Kuniaki Arai,Tatsuya Yamashita,Yoshio Sakai,Shuichi Kaneko International Journal of Cancer 129 7 1576 2011/10/01
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- Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma. Hodo Y,Hashimoto S,Honda M,Yamashita T,Suzuki Y,Sugano S,Kaneko S,Matsushima K Genomics 95 4 217 2010/04
- Endothelial to Mesenchymal Transition via Transforming Growth Factor-beta 1/Smad Activation Is Associated with Portal Venous Stenosis in Idiopathic Portal Hypertension Azusa Kitao,Yasunori Sato,Seiko Sawada-Kitamura,Kenichi Harada,Motoko Sasaki,Hiroyasu Morikawa,Susumu Shiomi,Masao Honda,Osamu Matsui,Yasuni Nakanuma AMERICAN JOURNAL OF PATHOLOGY 175 2 616 2009/08
- Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma. Shunsuke Ura,Masao Honda,Taro Yamashita,Teruyuki Ueda,Hajime Takatori,Ryuhei Nishino,Hajime Sunakozaka,Yoshio Sakai,Katsuhisa Horimoto,Shuichi Kaneko Hepatology (Baltimore, Md.) 49 4 1098 2009/04
- Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C Yasuhito Tanaka,Nao Nishida,Masaya Sugiyama,Masayuki Kurosaki,Kentaro Matsuura,Naoya Sakamoto,Mina Nakagawa,Masaaki Korenaga,Keisuke Hino,Shuhei Hige,Yoshito Ito,Eiji Mita,Eiji Tanaka,Satoshi Mochida,Yoshikazu Murawaki,Masao Honda,Akito Sakai,Yoichi Hiasa,Shuhei Nishiguchi,Asako Koike,Isao Sakaida,Masatoshi Imamura,Kiyoaki Ito,Koji Yano,Naohiko Masaki,Fuminaka Sugauchi,Namiki Izumi,Katsushi Tokunaga,Masashi Mizokami NATURE GENETICS 41 10 1105 2009/10
- Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: Possible link to serum anti-endothelial cell antibodies Sato, Yasunori,Ren, Xiangshan,Harada, Kenichi,Sasaki, Motoko,Morikawa, Hiroyasu,Shiomi, Susumu,Honda, Masao,Kaneko, Shuichi,Nakanuma, Yasuni Clinical and Experimental Immunology 167 3 532 2012/03/01
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- A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma Takuji Okusaka,Hiroshi Kasugai,Hiroshi Ishii,Masatoshi Kudo,Michio Sata,Katsuaki Tanaka,Yasukazu Shioyama,Kazuaki Chayama,Hiromitsu Kumada,Masaharu Yoshikawa,Toshihito Seki,Hidetugu Saito,Naoaki Hayashi,Keiko Shiratori,Kiwamu Okita,Isao Sakaida,Masao Honda,Yukio Kusumoto,Takuya Tsutsumi,Kenji Sakata Investigational New Drugs 30 5 2015 2012/10
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- Expression of chondroitin-glucuronate C5-epimerase and cellular immune responses in patients with hepatocellular carcinoma. Eishiro Mizukoshi,Kazumi Fushimi,Kuniaki Arai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko Liver international : official journal of the International Association for the Study of the Liver 32 10 1516 2012/11
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- Association of interleukin-28B genotype and hepatocellular carcinoma recurrence in patients with chronic hepatitis C. Hodo Y,Honda M,Tanaka A,Nomura Y,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Sakai A,Sasaki M,Nakanuma Y,Moriyama M,Kaneko S Clinical cancer research : an official journal of the American Association for Cancer Research 19 7 1827 2013/04
- Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling. Ueda T,Honda M,Horimoto K,Aburatani S,Saito S,Yamashita T,Sakai Y,Nakamura M,Takatori H,Sunagozaka H,Kaneko S Genomics 101 4 238 2013/04
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- Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma. Masao Honda,Taro Yamashita,Tatsuya Yamashita,Kuniaki Arai,Yoshio Sakai,Akito Sakai,Mikiko Nakamura,Eishiro Mizukoshi,Shuichi Kaneko BMC cancer 13 191 2013/04/15
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- Prognosis of autoimmune hepatitis showing acute presentation Kazuhide Yamamoto,Yasuhiro Miyake,Hiromasa Ohira,Yoshiyuki Suzuki,Mikio Zeniya,Morikazu Onji,Hirohito Tsubouchi,Kaname Yoshizawa,Toshio Morizane,Toshifumi Hibi,Yutaka Aoyagi,Yasuni Nakanuma,Junko Hirohara,Hajime Takikawa,Hiromi Ishibashi,Shinji Shimoda,Shotaro Sakisaka,Makoto Nakamuta,Yasushi Matsuzaki,Toshiji Saibara,Yoshiyuki Ueno,Hiroshi Miyakawa,Norihiro Kokudo,Hiroto Egawa,Yoshihiko Maehara,Satoshi Mochida,Isao Sakaida,Tomoo Fujisawa,Kazuyuki Suzuki,Kazuaki Inoue,Takafumi Ichida,Osamu Yokosuka,Hiroshi Fukui,Hisataka Moriwaki,Mitsuru Mori,Toshiyuki Mori,Masato Nagino,Naohiro Sata,Susumu Tazuma,Takahiro Yasaka,Toshio Tsuyuguchi,Junichi Shoda,Masao Honda,Hiroki Yamaue,Michiaki Unno,Norio Hayashi Hepatology Research 43 6 630 2013/06
- Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model. Akihiro Seki,Yoshio Sakai,Takuya Komura,Alessandro Nasti,Keiko Yoshida,Mami Higashimoto,Masao Honda,Soichiro Usui,Masayuki Takamura,Toshinari Takamura,Takahiro Ochiya,Kengo Furuichi,Takashi Wada,Shuichi Kaneko Hepatology (Baltimore, Md.) 58 3 1133 2013/09
- Acyclic Retinoid Targets Platelet-Derived Growth Factor Signaling in the Prevention of Hepatic Fibrosis and Hepatocellular Carcinoma Development Hikari Okada,Masao Honda,Jean S. Campbell,Yoshio Sakai,Taro Yamashita,Yuuki Takebuchi,Kazuhiro Hada,Takayoshi Shirasaki,Riuta Takabatake,Mikiko Nakamura,Hajime Sunagozaka,Takuji Tanaka,Nelson Fausto,Shuichi Kaneko CANCER RESEARCH 72 17 4459 2012/09
- 前臨床非アルコール性肝炎肝硬変マウスモデルに対する脂肪組織由来間質細胞投与による肝修復再生治療効果の検討 酒井佳夫,関晃裕,東元真実,吉田佳子,ナスティアレッサンドロ,小村卓也,本多政夫,金子周一,号:Supplement,ページ Acta Hepatologica Japonica 2014/04
- The Acyclic Retinoid Peretinoin Inhibits Hepatitis C Virus Replication and Infectious Virus Release in Vitro Tetsuro Shimakami,Masao Honda,Takayoshi Shirasaki,Riuta Takabatake,Fanwei Liu,Kazuhisa Murai,Takayuki Shiomoto,Masaya Funaki,Daisuke Yamane,Seishi Murakami,Stanley M. Lemon,Shuichi Kaneko SCIENTIFIC REPORTS 4 4688 2014/04
- Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+ T-cell suppression. Mami Higashimoto,Yoshio Sakai,Masayuki Takamura,Soichiro Usui,Alessandro Nasti,Keiko Yoshida,Akihiro Seki,Takuya Komura,Masao Honda,Takashi Wada,Kengo Furuichi,Takahiro Ochiya,Shuichi Kaneko European journal of immunology 43 11 2956 2013/11
- The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma. Zeng SS,Yamashita T,Kondo M,Nio K,Hayashi T,Hara Y,Nomura Y,Yoshida M,Hayashi T,Oishi N,Ikeda H,Honda M,Kaneko S Journal of hepatology 60 1 127 2014/01
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- Association of changes in the gene expression profile of blood cells with the local tumor inflammatory response in a murine tumor model. Sakai Y,Tatsumi I,Higashimoto M,Seki A,Nasti A,Yoshida K,Kawaguchi K,Wada T,Honda M,Komura T,Kaneko S Biochemical and biophysical research communications 428 1 36 2012/11
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- The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial Yumie Takeshita,Toshinari Takamura,Masao Honda,Yuki Kita,Yoh Zen,Ken-ichiro Kato,Hirofumi Misu,Tsuguhito Ota,Mikiko Nakamura,Kazutoshi Yamada,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Shuichi Kaneko DIABETOLOGIA 57 5 878 2014/05
- microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection. Spaniel C,Honda M,Selitsky SR,Yamane D,Shimakami T,Kaneko S,Lanford RE,Lemon SM PloS one 8 10 e76867 2013
- Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update Shuichi Kaneko,Junji Furuse,Masatoshi Kudo,Kenji Ikeda,Masao Honda,Yasunari Nakamoto,Morikazu Onchi,Goshi Shiota,Osamu Yokosuka,Isao Sakaida,Tetsuo Takehara,Yoshiyuki Ueno,Kazumasa Hiroishi,Shuhei Nishiguchi,Hisataka Moriwaki,Kazuhide Yamamoto,Michio Sata,Shuntaro Obi,Shiro Miyayama,Yukinori Imai HEPATOLOGY RESEARCH 42 6 523 2012/06
- P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma. Terashima T,Mizukoshi E,Arai K,Yamashita T,Yoshida M,Ota H,Onishi I,Kayahara M,Ohtsubo K,Kagaya T,Honda M,Kaneko S Cancer immunology, immunotherapy : CII 63 5 479 2014/05
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- New Susceptibility and Resistance HLA-DP Alleles to HBV-Related Diseases Identified by a Trans-Ethnic Association Study in Asia Nao Nishida,Hiromi Sawai,Koichi Kashiwase,Mutsuhiko Minami,Masaya Sugiyama,Wai-Kay Seto,Man-Fung Yuen,Nawarat Posuwan,Yong Poovorawan,Sang Hoon Ahn,Kwang-Hyub Han,Kentaro Matsuura,Yasuhito Tanaka,Masayuki Kurosaki,Yasuhiro Asahina,Namiki Izumi,Jong-Hon Kang,Shuhei Hige,Tatsuya Ide,Kazuhide Yamamoto,Isao Sakaida,Yoshikazu Murawaki,Yoshito Itoh,Akihiro Tamori,Etsuro Orito,Yoichi Hiasa,Masao Honda,Shuichi Kaneko,Eiji Mita,Kazuyuki Suzuki,Keisuke Hino,Eiji Tanaka,Satoshi Mochida,Masaaki Watanabe,Yuichiro Eguchi,Naohiko Masaki,Kazumoto Murata,Masaaki Korenaga,Yoriko Mawatari,Jun Ohashi,Minae Kawashima,Katsushi Tokunaga,Masashi Mizokami PLOS ONE 9 2 e86449 2014/02
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- Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C. Etsuko Iio,Kentaro Matsuura,Nao Nishida,Shinya Maekawa,Nobuyuki Enomoto,Mina Nakagawa,Naoya Sakamoto,Hiroshi Yatsuhashi,Masayuki Kurosaki,Namiki Izumi,Yoichi Hiasa,Naohiko Masaki,Tatsuya Ide,Keisuke Hino,Akihiro Tamori,Masao Honda,Shuichi Kaneko,Satoshi Mochida,Hideyuki Nomura,Shuhei Nishiguchi,Chiaki Okuse,Yoshito Itoh,Hitoshi Yoshiji,Isao Sakaida,Kazuhide Yamamoto,Hisayoshi Watanabe,Shuhei Hige,Akihiro Matsumoto,Eiji Tanaka,Katsushi Tokunaga,Yasuhito Tanaka Hum Genet 134 3 279 2015/03
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- Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice Hikari Okada,Masao Honda,Jean S. Campbell,Kai Takegoshi,Yoshio Sakai,Taro Yamashita,Takayoshi Shirasaki,Riuta Takabatake,Mikiko Nakamura,Takuji Tanaka,Shuichi Kaneko CANCER SCIENCE 106 9 1143 2015/09
- Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer. Kawaguchi K,Honda M,Yamashita T,Okada H,Shirasaki T,Nishikawa M,Nio K,Arai K,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S The American journal of pathology 186 8 2055 2016/08
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- Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C. Etsuko Iio,Kentaro Matsuura,Nao Nishida,Shinya Maekawa,Nobuyuki Enomoto,Mina Nakagawa,Naoya Sakamoto,Hiroshi Yatsuhashi,Masayuki Kurosaki,Namiki Izumi,Yoichi Hiasa,Naohiko Masaki,Tatsuya Ide,Keisuke Hino,Akihiro Tamori,Masao Honda,Shuichi Kaneko,Satoshi Mochida,Hideyuki Nomura,Shuhei Nishiguchi,Chiaki Okuse,Yoshito Itoh,Hitoshi Yoshiji,Isao Sakaida,Kazuhide Yamamoto,Hisayoshi Watanabe,Shuhei Hige,Akihiro Matsumoto,Eiji Tanaka,Katsushi Tokunaga,Yasuhito Tanaka Human genetics 134 3 279 2015/03
- Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems. Liu F,Shimakami T,Murai K,Shirasaki T,Funaki M,Honda M,Murakami S,Yi M,Tang H,Kaneko S Scientific reports 6 30939 2016/08
- A hybrid model for hepatitis B virus Ben-Gong Zhang,Gouhei Tanaka,Kazuyuki Aihara,Masao Honda,Shuichi Kaneko,Luonan Chen IFAC-PapersOnLine 28 18 37 2015/11/01
- Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis Kazutoshi Yamada,Eishiro Mizukoshi,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Yumie Takeshita,Hirofumi Misu,Toshinari Takamura,Seiko Kitamura,Yoh Zen,Yasuni Nakanuma,Masao Honda,Shuichi Kaneko LIVER INTERNATIONAL 35 6 1773 2015/06
- Altered gene expression in T-cell receptor signalling in peripheral blood leucocytes in acute coronary syndrome predicts secondary coronary events. Takashima S,Usui S,Kurokawa K,Kitano T,Kato T,Murai H,Furusho H,Oda H,Maruyama M,Nagata Y,Usuda K,Kubota K,Takeshita Y,Sakai Y,Honda M,Kaneko S,Takamura M Open heart 3 1 e000400 2016
- Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. Sara R Selitsky,Timothy A Dinh,Cynthia L Toth,C Lisa Kurtz,Masao Honda,Benjamin R Struck,Shuichi Kaneko,Kasey C Vickers,Stanley M Lemon,Praveen Sethupathy mBio 6 6 e01500-15 2015/12/08
- Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma. Terashima T,Yamashita T,Horii R,Arai K,Kawaguchi K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S BMC cancer 16 338 2016/05
- Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma. Honda M,Shirasaki T,Terashima T,Kawaguchi K,Nakamura M,Oishi N,Wang X,Shimakami T,Okada H,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S The Journal of infectious diseases 213 7 1096 2016/04
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- Feasibility and efficacy of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma after sorafenib. Terashima T,Yamashita T,Arai K,Sunagozaka H,Kitahara M,Nakagawa H,Kagaya T,Mizukoshi E,Honda M,Kaneko S Hepatology research : the official journal of the Japan Society of Hepatology 44 12 1179 2014/11
- Response to chemotherapy improves hepatic reserve for patients with hepatocellular carcinoma and Child-Pugh B cirrhosis. Takeshi Terashima,Tatsuya Yamashita,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko Cancer science 107 9 1263 2016/09
- Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib. Terashima T,Yamashita T,Takata N,Nakagawa H,Toyama T,Arai K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S Hepatology research : the official journal of the Japan Society of Hepatology 46 7 650 2016/06
- Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis Nao Nishida,Jun Ohashi,Seik-Soon Khor,Masaya Sugiyama,Takayo Tsuchiura,Hiromi Sawai,Keisuke Hino,Masao Honda,Shuichi Kaneko,Hiroshi Yatsuhashi,Osamu Yokosuka,Kazuhiko Koike,Masayuki Kurosaki,Namiki Izumi,Masaaki Korenaga,Jong-Hon Kang,Eiji Tanaka,Akinobu Taketomi,Yuichiro Eguchi,Naoya Sakamoto,Kazuhide Yamamoto,Akihiro Tamori,Isao Sakaida,Shuhei Hige,Yoshito Itoh,Satoshi Mochida,Eiji Mita,Yasuhiro Takikawa,Tatsuya Ide,Yoichi Hiasa,Hiroto Kojima,Ken Yamamoto,Minoru Nakamura,Hiroh Saji,Takehiko Sasazuki,Tatsuya Kanto,Katsushi Tokunaga,Masashi Mizokami SCIENTIFIC REPORTS 6 24767 2016/04
- Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication Hiroe Sejima,Shinya Satoh,Hiromichi Dansako,Masao Honda,Shuichi Kaneko,Masanori Ikeda,Nobuyuki Kato ACTA MEDICA OKAYAMA 70 2 75 2016/04
- Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma. Nio K,Yamashita T,Okada H,Kondo M,Hayashi T,Hara Y,Nomura Y,Zeng SS,Yoshida M,Hayashi T,Sunagozaka H,Oishi N,Honda M,Kaneko S Journal of hepatology 63 5 1164 2015/11
- TSU-68 ameliorates hepatocellular carcinoma growth by inhibiting microenvironmental platelet-derived growth factor signaling. Hara Y,Yamashita T,Oishi N,Nio K,Hayashi T,Nomura Y,Yoshida M,Hayashi T,Hashiba T,Asahina Y,Kondo M,Okada H,Sunagozaka H,Honda M,Kaneko S Anticancer research 35 3 1423 2015/03
- Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis Kazutoshi Yamada,Eishiro Mizukoshi,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Yumie Takeshita,Hirofumi Misu,Toshinari Takamura,Seiko Kitamura,Yoh Zen,Yasuni Nakanuma,Masao Honda,Shuichi Kaneko LIVER INTERNATIONAL 35 2 582 2015/02
- Dynamics of an HBV Model with Drug Resistance Under Intermittent Antiviral Therapy. Array,Gouhei Tanaka,Kazuyuki Aihara,Masao Honda,Shuichi Kaneko,Luonan Chen I. J. Bifurcation and Chaos 25 7 2015
- Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway Takayoshi Shirasaki,Masao Honda,Tetsuro Shimakami,Kazuhisa Murai,Takayuki Shiomoto,Hikari Okada,Riuta Takabatake,Akihiro Tokumaru,Yoshio Sakai,Taro Yamashita,Stanley M. Lemon,Seishi Murakami,Shuichi Kaneko Hepatology 60 5 1519 2014/11/01
- [Diagnostic benefits of adrenocortical scintigraphy in hepatic adrenal rest tumor]. Ishida K,Horii R,Yamashita T,Arai K,Yamashita T,Kagaya T,Sakai Y,Mizukoshi E,Honda M,Kaneko S Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 111 10 2004 2014/10
- Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma. Hayashi T,Yamashita T,Okada H,Nio K,Hara Y,Nomura Y,Hayashi T,Asahina Y,Yoshida M,Oishi N,Sunagozaka H,Takatori H,Honda M,Kaneko S Cancer cell international 17 94 2017
- Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet. Hikari Okada,Riuta Takabatake,Masao Honda,Kai Takegoshi,Taro Yamashita,Mikiko Nakamura,Takayoshi Shirasaki,Yoshio Sakai,Tetsuro Shimakami,Naoto Nagata,Toshinari Takamura,Takuji Tanaka,Shuichi Kaneko Oncotarget 8 25 39978 2017/06/20
- The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis Hirayuki Enomoto,Lihua Tao,Ryoji Eguchi,Ayuko Sato,Masao Honda,Shuichi Kaneko,Yoshinori Iwata,Hiroki Nishikawa,Hiroyasu Imanishi,Hiroko Iijima,Tohru Tsujimura,Shuhei Nishiguchi SCIENTIFIC REPORTS 7 2017/09
- Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease Kazutoshi Yamada,Eishiro Mizukoshi,Takuya Seike,Rika Horii,Masaaki Kitahara,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko PLoS ONE 13 1 e0191026 2018/01/01
- Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B Xuyang Wang,Naoki Oishi,Tetsuro Shimakami,Taro Yamashita,Masao Honda,Seishi Murakami,Shuichi Kaneko WORLD JOURNAL OF GASTROENTEROLOGY 23 18 3252 2017/05
- Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3 ' variants Daisuke Yamane,Sara R. Selitsky,Tetsuro Shimakami,You Li,Mi Zhou,Masao Honda,Praveen Sethupathy,Stanley M. Lemon NUCLEIC ACIDS RESEARCH 45 8 4743 2017/05
- Prognosis of type 1 autoimmune pancreatitis after corticosteroid therapy-induced remission in terms of relapse and diabetes mellitus Masaki Miyazawa,Hajime Takatori,Tetsuro Shimakami,Kazunori Kawaguchi,Kazuya Kitamura,Kuniaki Arai,Koichiro Matsuda,Taku Sanada,Takeshi Urabe,Katsuhisa Inamura,Takashi Kagaya,Hideki Mizuno,Uichiro Fuchizaki,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko PLOS ONE 12 11 e0188549 2017/11
- Direct-acting antiviral agents improved nephrotic syndrome associated with refractory pleural effusion and ascites caused by hepatitis C virus-related nephropathy: a case report. Yamato M,Arai K,Takatori H,Shimakami T,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Honda M,Kaneko S Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 114 6 1031 2017
- Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma. Komura T,Takabatake H,Harada K,Yamato M,Miyazawa M,Yoshida K,Honda M,Wada T,Kitagawa H,Ohta T,Kaneko S,Sakai Y Cancer science 108 11 2122 2017/11
- Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model Kai Takegoshi,Masao Honda,Hikari Okada,Riuta Takabatake,Naoto Matsuzawa-Nagata,Jean S. Campbell,Masashi Nishikawa,Tetsuro Shimakami,Takayoshi Shirasaki,Yoshio Sakai,Taro Yamashita,Toshinari Takamura,Takuji Tanaka,Shuichi Kaneko ONCOTARGET 8 11 18191 2017/03
- The CD45(+) fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells Alessandro Nasti,Yoshio Sakai,Akihiro Seki,Geraldine Belen Buffa,Takuya Komura,Hatsune Mochida,Masatoshi Yamato,Keiko Yoshida,Tuyen T. B. Ho,Masayuki Takamura,Soichiro Usui,Takashi Wada,Masao Honda,Shuichi Kaneko EUROPEAN JOURNAL OF IMMUNOLOGY 47 12 2163 2017/12
- Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection. Murata K,Asano M,Matsumoto A,Sugiyama M,Nishida N,Tanaka E,Inoue T,Sakamoto M,Enomoto N,Shirasaki T,Honda M,Kaneko S,Gatanaga H,Oka S,Kawamura YI,Dohi T,Shuno Y,Yano H,Mizokami M Gut 67 2 362 2016/10
- Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma Takeshi Terashima,Tatsuya Yamashita,Kuniaki Arai,Kazunori Kawaguchi,Kazuya Kitamura,Taro Yamashita,Yoshio Sakai,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko LIVER CANCER 6 3 236 2017
- Phase I clinical study of liver regenerative therapy for cirrhosis by intrahepatic arterial infusion of freshly isolated autologous adipose tissue-derived stromal/stem (regenerative) cell Yoshio Sakai,Masayuki Takamura,Akihiro Seki,Hajime Sunagozaka,Takeshi Terashima,Takuya Komura,Masatoshi Yamato,Masaki Miyazawa,Kazunori Kawaguchi,Alessandro Nasti,Hatsune Mochida,Soichiro Usui,Nobuhisa Otani,Takahiro Ochiya,Takashi Wada,Masao Honda,Shuichi Kaneko REGENERATIVE THERAPY 6 52 2017/06
- Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study. Hayashi T,Yamashita T,Terashima T,Suda T,Okada H,Asahina Y,Hayashi T,Hara Y,Nio K,Sunagozaka H,Takatori H,Arai K,Sakai Y,Yamashita T,Mizukoshi E,Honda M,Kaneko S BMC cancer 17 1 870 2017/12
- Immune responses against tumour-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients. Kida A,Mizukoshi E,Tamai T,Terashima T,Kitahara M,Arai K,Yamashita T,Fushimi K,Honda M,Kaneko S Liver international : official journal of the International Association for the Study of the Liver 38 11 2040 2018/05
- Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection Kentaro Matsuura,Hiromi Sawai,Kazuho Ikeo,Shintaro Ogawa,Etsuko Iio,Masanori Isogawa,Noritomo Shimada,Atsumasa Komori,Hidenori Toyoda,Takashi Kumada,Tadashi Namisaki,Hitoshi Yoshiji,Naoya Sakamoto,Mina Nakagawa,Yasuhiro Asahina,Masayuki Kurosaki,Namiki Izumi,Nobuyuki Enomoto,Atsunori Kusakabe,Eiji Kajiwara,Yoshito Itoh,Tatsuya Ide,Akihiro Tamori,Misako Matsubara,Norifumi Kawada,Ken Shirabe,Eiichi Tomita,Masao Honda,Shuichi Kaneko,Sohji Nishina,Atsushi Suetsugu,Yoichi Hiasa,Hisayoshi Watanabe,Takuya Genda,Isao Sakaida,Shuhei Nishiguchi,Koichi Takaguchi,Eiji Tanaka,Junichi Sugihara,Mitsuo Shimada,Yasuteru Kondo,Yosuke Kawai,Kaname Kojima,Masao Nagasaki,Katsushi Tokunaga,Yasuhito Tanaka Gastroenterology 152 6 1383 2017/05
- Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: Prospects for regorafenib therapy. Terashima T,Yamashita T,Sunagozaka H,Arai K,Kawaguchi K,Kitamura K,Yamashita T,Sakai Y,Mizukoshi E,Honda M,Kaneko S Hepatology research : the official journal of the Japan Society of Hepatology 48 12 956 2018/05
- Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population Kawashima, Minae,Hitomi, Yuki,Aiba, Yoshihiro,Nishida, Nao,Kojima, Kaname,Kawai, Yosuke,Nakamura, Hitomi,Tanaka, Atsushi,Zeniya, Mikio,Hashimoto, Etsuko,Ohira, Hiromasa,Yamamoto, Kazuhide,Abe, Masanori,Nakao, Kazuhiko,Yamagiwa, Satoshi,Kaneko, Shuichi,Honda, Masao,Umemura, Takeji,Ichida, Takafumi,Seike, Masataka,Sakisaka, Shotaro,Harada, Masaru,Yokosuka, Osamu,Ueno, Yoshiyuki,Senju, Michio,Kanda, Tatsuo,Shibata, Hidetaka,Himoto, Takashi,Murata, Kazumoto,Miyake, Yasuhiro,Ebinuma, Hirotoshi,Taniai, Makiko,Joshita, Satoru,Nikami, Toshiki,Ota, Hajime,Kouno, Hiroshi,Kouno, Hirotaka,Nakamuta, Makoto,Fukushima, Nobuyoshi,Kohjima, Motoyuki,Komatsu, Tatsuji,Komeda, Toshiki,Ohara, Yukio,Muro, Toyokichi,Yamashita, Tsutomu,Yoshizawa, Kaname,Nakamura, Yoko,Shimada, Masaaki,Hirashima, Noboru,Sugi, Kazuhiro,Ario, Keisuke,Takesaki, Eiichi,Naganuma, Atsushi,Mano, Hiroshi,Yamashita, Haruhiro,Matsushita, Kouki,Yamauchi, Kazuhiko,Makita, Fujio,Nishimura, Hideo,Furuta, Kiyoshi,Takahashi, Naohiro,Kikuchi, Masahiro,Masaki, Naohiko,Tanaka, Tomohiro,Tamura, Sumito,Mori, Akira,Yagi, Shintaro,Shirabe, Ken,Komori, Atsumasa,Migita, Kiyoshi,Ito, Masahiro,Nagaoka, Shinya,Abiru, Seigo,Yatsuhashi, Hiroshi,Yasunami, Michio,Shimoda, Shinji,Harada, Kenichi,Egawa, Hiroto,Maehara, Yoshihiko,Uemoto, Shinji,Kokudo, Norihiro,Takikawa, Hajime,Ishibashi, Hiromi,Chayama, Kazuaki,Mizokami, Masashi,Nagasaki, Masao,Tokunaga, Katsushi,Nakamura, Minoru HUMAN MOLECULAR GENETICS 26 3 650 2017/02/01
- De Novo Emergence of Mesenchymal Stem-Like CD105+ Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma. Nomura Y,Yamashita T,Oishi N,Nio K,Hayashi T,Yoshida M,Hayashi T,Hashiba T,Asahina Y,Okada H,Sunagozaka H,Takatori H,Honda M,Kaneko S Translational oncology 10 2 184 2017/04
- Sorafenib suppresses extrahepatic metastasis de novo in hepatocellular carcinoma through inhibition of mesenchymal cancer stem cells characterized by the expression of CD90. Yoshida M,Yamashita T,Okada H,Oishi N,Nio K,Hayashi T,Nomura Y,Hayashi T,Asahina Y,Ohwada M,Sunagozaka H,Takatori H,Colombo F,Porretti L,Honda M,Kaneko S Scientific reports 7 1 11292 2017/09
- Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B. Kawaguchi K,Honda M,Ohta H,Terashima T,Shimakami T,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Komura T,Unoura M,Kaneko S Journal of gastroenterology 53 6 740 2018/06
- Unexpected Replication Boost by Simeprevir for Simeprevir-Resistant Variants in Genotype 1a Hepatitis C Virus. Murai K,Shimakami T,Welsch C,Shirasaki T,Liu F,Kitabayashi J,Tanaka S,Funaki M,Omura H,Nishikawa T,Sumiyadorj A,Honda M,Kaneko S Antimicrobial agents and chemotherapy 62 7 2018/07
- Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells. Sakai Y,Honda M,Matsui S,Komori O,Murayama T,Fujiwara T,Mizuno M,Imai Y,Yoshimura K,Nasti A,Wada T,Iida N,Kitahara M,Horii R,Toshikatsu T,Nishikawa M,Okafuji H,Mizukoshi E,Yamashita T,Yamashita T,Arai K,Kitamura K,Kawaguchi K,Takatori H,Shimakami T,Terashima T,Hayashi T,Nio K,Kaneko S,Hokuriku Liver,Study Group Cancer science 110 4 1364 2019/04
- Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis. Yamada K,Mizukoshi E,Seike T,Horii R,Terashima T,Iida N,Kitahara M,Sunagozaka H,Arai K,Yamashita T,Honda M,Takamura T,Harada K,Kaneko S Journal of gastroenterology and hepatology 34 10 1829 2019/10
- Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis. Kanno M,Kawaguchi K,Honda M,Horii R,Takatori H,Shimakami T,Kitamura K,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Kaneko S Journal of gastroenterology 54 6 549 2019/06
- Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host. Jun Seishima,Noriho Iida,Kazuya Kitamura,Masahiro Yutani,Ziyu Wang,Akihiro Seki,Taro Yamashita,Yoshio Sakai,Masao Honda,Tatsuya Yamashita,Takashi Kagaya,Yukihiro Shirota,Yukako Fujinaga,Eishiro Mizukoshi,Shuichi Kaneko Genome biology 20 1 252 2019/11/25
- Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation. Masatoshi Yamato,Yoshio Sakai,Hatsune Mochida,Kazunori Kawaguchi,Masayuki Takamura,Soichiro Usui,Akihiro Seki,Eishiro Mizukoshi,Taro Yamashita,Tatsuya Yamashita,Kousuke Ishida,Alessandro Nasti,Ho Thuy Bich Tuyen,Takuya Komura,Keiko Yoshida,Takashi Wada,Masao Honda,Shuichi Kaneko Journal of gastroenterology and hepatology 34 8 1432 2019/08
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- Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation. Wang Z,Kawaguchi K,Honda M,Hashimoto S,Shirasaki T,Okada H,Orita N,Shimakami T,Yamashita T,Sakai Y,Mizukoshi E,Murakami S,Kaneko S Scientific reports 9 1 1621 2019/02
- Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis Shinya Satoh,Daichi Onomura,Youki Ueda,Hiromichi Dansako,Masao Honda,Shuichi Kaneko,Nobuyuki Kato Biochemical Journal 476 1 137 2019/01/15 ?
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- Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity. Kazuhisa Murai,Masao Honda,Takayoshi Shirasaki,Tetsuro Shimakami,Hitoshi Omura,Hirofumi Misu,Yuki Kita,Yumie Takeshita,Kiyo-Aki Ishii,Toshinari Takamura,Takeshi Urabe,Ryogo Shimizu,Hikari Okada,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko Cell host & microbe 25 4 588 2019/04/10
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- ヒト非B非C肝癌におけるシングルセル遺伝子発現解析(Single-cell transcriptome analysis in human NBNC hepatocellular carcinoma) 岩淵 禎弘,川口 和紀,本多 政夫,山下 太郎,山下 竜也,金子 周一,橋本 真一 日本癌学会総会記事 78回 P 2019/09
- ヒト非B非C肝癌におけるシングルセル遺伝子発現解析(Single-cell transcriptome analysis in human NBNC hepatocellular carcinoma) 岩淵 禎弘,川口 和紀,本多 政夫,山下 太郎,山下 竜也,金子 周一,橋本 真一 日本癌学会総会記事 78回 P 2019/09
- MicroRNA-10a Impairs Liver Metabolism in Hepatitis C Virus-Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator-Like 1. Rika Horii,Masao Honda,Takayoshi Shirasaki,Tetsuro Shimakami,Ryogo Shimizu,Souma Yamanaka,Kazuhisa Murai,Kazunori Kawaguchi,Kuniaki Arai,Tatsuya Yamashita,Yoshio Sakai,Taro Yamashita,Hikari Okada,Mikiko Nakamura,Eishiro Mizukoshi,Shuichi Kaneko Hepatology communications 3 12 1687 2019/12
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- Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models. Sakai Y,Miyazawa M,Komura T,Yamada T,Nasti A,Yoshida K,Takabatake H,Yamato M,Yamashita T,Yamashita T,Mizukoshi E,Okuzono M,Ho TTB,Kawaguchi K,Wada T,Honda M,Kaneko S Cancer Sci 110 3 903 2019/03
- Characteristics of Impaired Dendritic Cell Function in Patients With Hepatitis B Virus Infection. Yonejima A,Mizukoshi E,Tamai T,Nakagawa H,Kitahara M,Yamashita T,Arai K,Terashima T,Iida N,Fushimi K,Okada H,Yamashita T,Sakai Y,Honda M,Kaneko S Hepatology (Baltimore, Md.) 70 1 25 2019/07
- Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma. Sawai H,Nishida N,Khor SS,Honda M,Sugiyama M,Baba N,Yamada K,Sawada N,Tsugane S,Koike K,Kondo Y,Yatsuhashi H,Nagaoka S,Taketomi A,Fukai M,Kurosaki M,Izumi N,Kang JH,Murata K,Hino K,Nishina S,Matsumoto A,Tanaka E,Sakamoto N,Ogawa K,Yamamoto K,Tamori A,Yokosuka O,Kanda T,Sakaida I,Itoh Y,Eguchi Y,Oeda S,Mochida S,Yuen MF,Seto WK,Poovorawan Y,Posuwan N,Mizokami M,Tokunaga K Scientific reports 8 1 7958 2018/05
- POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33. Hitomi Y,Ueno K,Kawai Y,Nishida N,Kojima K,Kawashima M,Aiba Y,Nakamura H,Kouno H,Kouno H,Ohta H,Sugi K,Nikami T,Yamashita T,Katsushima S,Komeda T,Ario K,Naganuma A,Shimada M,Hirashima N,Yoshizawa K,Makita F,Furuta K,Kikuchi M,Naeshiro N,Takahashi H,Mano Y,Yamashita H,Matsushita K,Tsunematsu S,Yabuuchi I,Nishimura H,Shimada Y,Yamauchi K,Komatsu T,Sugimoto R,Sakai H,Mita E,Koda M,Nakamura Y,Kamitsukasa H,Sato T,Nakamuta M,Masaki N,Takikawa H,Tanaka A,Ohira H,Zeniya M,Abe M,Kaneko S,Honda M,Arai K,Arinaga-Hino T,Hashimoto E,Taniai M,Umemura T,Joshita S,Nakao K,Ichikawa T,Shibata H,Takaki A,Yamagiwa S,Seike M,Sakisaka S,Takeyama Y,Harada M,Senju M,Yokosuka O,Kanda T,Ueno Y,Ebinuma H,Himoto T,Murata K,Shimoda S,Nagaoka S,Abiru S,Komori A,Migita K,Ito M,Yatsuhashi H,Maehara Y,Uemoto S,Kokudo N,Nagasaki M,Tokunaga K,Nakamura M Scientific reports 9 1 102 2019/01 ?
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- Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis. Noriho Iida,Eishiro Mizukoshi,Tatsuya Yamashita,Masahiro Yutani,Jun Seishima,Ziyu Wang,Kuniaki Arai,Hikari Okada,Taro Yamashita,Yoshio Sakai,Yusuke Masuo,Rina Agustina,Yukio Kato,Yukako Fujinaga,Masanobu Oshima,Masao Honda,François Lebreton,Michael S Gilmore,Shuichi Kaneko Nature cancer 2 10 1039 2021/10
- Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice. Takayoshi Shirasaki,Kazuhisa Murai,Masao Honda,Hikari Okada,Yuika Innami,Atsumu Yamada,Tetsuro Shimakami,Kazunori Kawaguchi,Taro Yamashita,Yoshio Sakai,Shuichi Kaneko Scientific reports 11 1 13021 2021/06/22
- Effect of adoptive T-cell immunotherapy on immunological parameters and prognosis in patients with advanced pancreatic cancer. Tatsuo Kumai,Eishiro Mizukoshi,Tomomi Hashiba,Hidetoshi Nakagawa,Masaaki Kitahara,Tomoharu Miyashita,Takafumi Mochizuki,Shigenori Goto,Takashi Kamigaki,Rishu Takimoto,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Katsuro Tomita,Shuichi Kaneko Cytotherapy 23 2 137 2021/02
- Efficacy of a novel self-expandable metal stent with dumbbell-shaped flare ends for distal biliary obstruction due to unresectable pancreatic cancer. Masaki Miyazawa,Hajime Takatori,Hirofumi Okafuji,Tomoyuki Hayashi,Tadashi Toyama,Shinya Yamada,Kazuya Kitamura,Kuniaki Arai,Yoshio Sakai,Taro Yamashita,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko Scientific reports 12 1 21100 2022/12/06
- Preexisting Humoral Immunity Cross-Reacting with SARS-CoV-2 Might Prevent Death Due to COVID-19 in Critical Patients Taro Yamashita,Tetsuro Shimakami,Kouki Nio,Takeshi Terashima,Masaki Okajima,Takumi Taniguchi,Takashi Wada,Masao Honda,Toshifumi Gabata,Kenji Ota,Katsunori Yanagihara,Shuichi Kaneko Journal of Clinical Medicine 11 13 3870 2022/07/04 ?
- A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes. Ariunaa Sumiyadorj,Kazuhisa Murai,Tetsuro Shimakami,Kazuyuki Kuroki,Tomoki Nishikawa,Masaki Kakuya,Atsumu Yamada,Ying Wang,Atsuya Ishida,Takayoshi Shirasaki,Shotaro Kawase,Ying-Yi Li,Hikari Okada,Kouki Nio,Kazunori Kawaguchi,Taro Yamashita,Yoshio Sakai,Davaadorj Duger,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko Hepatology communications 2022/06/12
- Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8+ T cells. Eishiro Mizukoshi,Hidetoshi Nakagawa,Toshikatsu Tamai,Masaaki Kitahara,Kazumi Fushimi,Kouki Nio,Takeshi Terashima,Noriho Iida,Kuniaki Arai,Tatsuya Yamashita,Taro Yamashita,Yoshio Sakai,Masao Honda,Shuichi Kaneko Nature communications 13 1 3123 2022/06/03
- Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut. Hirofumi Okafuji,Noriho Iida,Kazuya Kitamura,Jun Seishima,Ziyu Wang,Masahiro Yutani,Takatoshi Yoshio,Taro Yamashita,Yoshio Sakai,Masao Honda,Tatsuya Yamashita,Yukako Fujinaga,Reiko Shinkura,Yasuhito Hamaguchi,Eishiro Mizukoshi,Shuichi Kaneko Digestion 1 2022/02/18
- FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition. Ru Li,Hikari Okada,Taro Yamashita,Kouki Nio,Han Chen,Yingyi Li,Tetsuro Shimakami,Hajime Takatori,Kuniaki Arai,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko International journal of molecular sciences 23 15 2022/07/27
- Comparison of Tofogliflozin and Glimepiride Effects on Nonalcoholic Fatty Liver Disease in Participants With Type 2 Diabetes: A Randomized, 48-Week, Open-Label, Active-Controlled Trial. Yumie Takeshita,Masao Honda,Kenichi Harada,Yuki Kita,Noboru Takata,Hiromasa Tsujiguchi,Takeo Tanaka,Hisanori Goto,Yujiro Nakano,Noriho Iida,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Hiroyuki Nakamura,Shuichi Kaneko,Toshinari Takamura Diabetes care 45 9 2064 2022/09/01
- Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma Tsuyoshi Suda,Taro Yamashita,Hajime Sunagozaka,Hikari Okada,Kouki Nio,Yoshio Sakai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Shuichi Kaneko International Journal of Molecular Sciences 23 5 2801 2022/03/03 ?
- Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals. Shihui Li,Eishiro Mizukoshi,Kazunori Kawaguchi,Miyabi Miura,Michiko Nishino,Tetsuro Shimakami,Kuniaki Arai,Taro Yamashita,Yoshio Sakai,Tatsuya Yamashita,Masao Honda,Shuichi Kaneko International journal of molecular sciences 23 19 2022/10/01
- 肝細胞腺腫の新たな亜型の同定(Identification of a new subtype of hepatocellular adenoma) 岩淵 禎弘,川口 和紀,本多 政夫,橋本 真一 日本癌学会総会記事 81回 P 2022/09
- Hepatitis B virus utilizes a retrograde trafficking route via the trans-Golgi network to avoid lysosomal degradation. Ying-Yi Li,Kazuyuki Kuroki,Tetsuro Shimakami,Kazuhisa Murai,Kazunori Kawaguchi,Takayoshi Shirasaki,Kouki Nio,Saiho Sugimoto,Tomoki Nishikawa,Hikari Okada,Noriaki Orita,Hideo Takayama,Ying Wang,Phuong Doan Thi Bich,Astuya Ishida,Sadahiro Iwabuchi,Shinichi Hashimoto,Takeshi Shimaoka,Noriko Tabata,Miho Watanabe-Takahashi,Kiyotaka Nishikawa,Hiroshi Yanagawa,Motoharu Seiki,Kouji Matsushima,Taro Yamashita,Shuichi Kaneko,Masao Honda Cellular and molecular gastroenterology and hepatology 15 3 533 2022/10/18
- Plasma Antithrombin III Levels Can Be a Prognostic Factor in Liver Cirrhosis Patients with Portal Vein Thrombosis Tsuyoshi Suda,Hajime Takatori,Takehiro Hayashi,Kiichiro Kaji,Kouki Nio,Takeshi Terashima,Tetsuro Shimakami,Kuniaki Arai,Tatsuya Yamashita,Eishiro Mizukoshi,Masao Honda,Kenichiro Okumura,Kazuto Kozaka,Taro Yamashita International Journal of Molecular Sciences 24 9 2023/04
- Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits Hepatitis B Virus infection and replication. Mayuko Ide,Noriko Tabata,Yuko Yonemura,Takayoshi Shirasaki,Kazuhisa Murai,Ying Wang,Atsuya Ishida,Hikari Okada,Masao Honda,Shuichi Kaneko,Nobuhide Doi,Satoru Ito,Hiroshi Yanagawa The Journal of biological chemistry 298 7 102097 2022/06/02
- Upregulation of the Long Noncoding RNA HULC by Hepatitis C Virus and Its Regulation of Viral Replication Kitabayashi J, Shirasaki T, Shimakami T, Nishiyama T, Welsch C, Funaki M, Murai K, Sumiyadorj A, Takatori H, Kitamura K, Kawaguchi K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S; Hokuriku Liver Study Group. J Infect Dis. 226 3 407 2022/08/26
- Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair. Yano M, Nasti A, Seki A, Ishida K, Yamato M, Inui H, Ogawa N, Inagaki S, Ho TTB, Kawaguchi K, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Inoue O, Takashima S, Usui S, Takamura M, Honda M, Wada T, Kaneko S, Sakai Y. Regen Ther. 18 497-507 2021/12/03
- Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis. Iida N, Mizukoshi E, Yamashita T, Yutani M, Seishima J, Wang Z, Arai K, Okada H, Yamashita T, Sakai Y, Masuo Y, Agustina R, Kato Y, Fujinaga Y, Oshima M, Honda M, Lebreton F, Gilmore MS, Kaneko S. Nat Cancer. 2 10 1039-1054 2021/10/01
- Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants. Yoshida K, Desbiolles A, Feldman SF, Ahn SH, Alidjinou EK, Atsukawa M, Bocket L, Brunetto MR, Buti M, Carey I, Caviglia GP, Chen EQ, Cornberg M, Enomoto M, Honda M, Zu Siederdissen CH, Ishigami M, Janssen HLA, Maasoumy B, Matsui T, Matsumoto A, Nishiguchi S, Riveiro-Barciela M, Takaki A, Tangkijvanich P, Toyoda H, van Campenhout MJH, Wang B, Wei L, Yang HI, Yano Y, Yatsuhashi H, Yuen MF, Tanaka E, Lemoine M, Tanaka Y, Shimakawa Y. Clin Gastroenterol Hepatol 19 1 46-60 2021/01/01
- Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis. Ho TTB, Nasti A, Seki A, Komura T, Inui H, Kozaka T, Kitamura Y, Shiba K, Yamashita T, Yamashita T, Mizukoshi E, Kawaguchi K, Wada T, Honda M, Kaneko S, Sakai Y. J Immunother Cancer. 8 2 e001367 2020/11/01
- Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial Yoshio Sakai, Shinya Fukunishi, Masayuki Takamura, Oto Inoue, Shinichiro Takashima, Soichiro Usui, Akihiro Seki, Alessandro Nasti, Tuyen Thuy Bich Ho, Kazunori Kawaguchi, Akira Asai, Yusuke Tsuchimoto, Taro Yamashita, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuhito Imai, Kenichi Yoshimura, Toshinori Murayama, Takashi Wada, Kenichi Harada, Kazuhide Higuchi, Shuichi Kaneko JMIR Res Protoc 9 3 e17904 2020/03/31
- Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation. Yamato M, Sakai Y, Mochida H, Kawaguchi K, Takamura M, Usui S, Seki A, Mizukoshi E, Yamashita T, Yamashita T, Ishida K, Nasti A, Tuyen HTB, Komura T, Yoshida K, Wada T, Honda M, Kaneko S. J Gastroenterol Hepatol. 34 8 1432-1440 2019/08/01
- Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells. Sakai Y, Honda M, Matsui S, Komori O, Murayama T, Fujiwara T, Mizuno M, Imai Y, Yoshimura K, Nasti A, Wada T, Iida N, Kitahara M, Horii R, Toshikatsu T, Nishikawa M, Okafuji H, Mizukoshi E, Yamashita T, Yamashita T, Arai K, Kitamura K, Kawaguchi K, Takatori H, Shimakami T, Terashima T, Hayashi T, Nio K, Kaneko S; Hokuriku Liver Study Group. Cancer Sci. 110 4 1364-1388 2019/04/01
- Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis. Kanno M, Kawaguchi K, Honda M, Horii R, Takatori H, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. J Gastroenterol. 54 6 549-557 2019/06/01
- A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma. Tamai T, Mizukoshi E, Kumagai M, Terashima T, Iida N, Kitahara M, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Honda M, Fushimi K, Kaneko S. Sci Rep 10 1 4021 2020/03/04
- Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice. Nishikawa T, Nagata N, Shimakami T, Shirakura T, Matsui C, Ni Y, Zhuge F, Xu L, Chen G, Nagashimada M, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S, Ota T. Sci Rep. 10 1 815 2020/01/21
- Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host. Seishima J, Iida N, Kitamura K, Yutani M, Wang Z, Seki A, Yamashita T, Sakai Y, Honda M, Yamashita T, Kagaya T, Shirota Y, Fujinaga Y, Mizukoshi E, Kaneko S. Genome Biol 20 1 252 2019/12/25
- MicroRNA‐10a Impairs Liver Metabolism in Hepatitis C Virus‐Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator‐Like 1. Horii R, Honda M*, Shirasaki T, Shimakami T, Shimizu R, Yamanaka S, Murai K, Kawaguchi K, Arai K, Yamashita T, Sakai Y, Yamashita T, Okada H, Nakamura M, Mizukoshi E, Kaneko S. Hepatol Commun 3 12 1687-1703 2019/09/26
- Characteristics of Impaired Dendritic Cell Function in Patients With Hepatitis B Virus Infection. Yonejima A, Mizukoshi E, Tamai T, Nakagawa H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Okada H, Yamashita T, Sakai Y, Honda M, Kaneko S. Hepatology 70 1 25-39 2019/07/01
- Establishment and Characterization of a New Cell Line Permissive for Hepatitis C Virus Infection. Sci Rep accepted in press. Omura H, Liu F, Shimakami T, Murai K, Shirasaki T, Kitabayashi T, Funaki M, Nishikawa T, Nakai R, Sumiyadorj A, Hayashi T, Yamashita , Honda H, Kaneko S. Sci Rep. 9 1 7943 2019/05/28
- Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation. Fujinaga H, Sakai Y, Yamashita T, Arai K, Terashima T, Komura T, Seki A, Kawaguchi K, Nasti A, Yoshida K, Wada T, Yamamoto K, Kume K, Hasegawa T, Takata T, Honda M, Kaneko S. Int J Radiat Biol. 95 5 571-579 2019/05/01
- Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Terashima T, Yamashita T, Toyama T, Arai K, Kawaguchi K, Kitamura K, Yamashita Liver Cancer. 8 2 130-139 2019/03/01
- Immune responses against tumour-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients. Kida A, Mizukoshi E, Tamai T, Terashima T, Kitahara M, Arai K, Yamashita T, Fushimi K, Honda M, Kaneko S. Liver Int. 38 11 2040-2050 2018/11/01
- Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: prospects for regorafenib therapy. Terashima T, Yamashita T, Sunagozaka H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Hepatol Res. 48 12 956-966 2018/11/01
- Three renal failure cases successfully treated with ombitasvir/paritaprevir/ritonavir for genotype 1b hepatitis C virus reinfection after liver transplantation. Orita N, Shimakami T, Sunagozaka H, Horii R, Nio K, Terashima T, Iida N, Kitahara M, Takatori H, Kawaguchi K, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Clin J Gastroenterol. 12 1 63-70 2019/02/01
- Characteristics of immune response to tumor-associated antigens and immune cell profile in hepatocellular carcinoma patients. Inada Y, Mizukoshi E, Seike T, Tamai T, Iida N, Kitahara M, Yamashita T, Arai K, Terashima T, Fushimi K, Yamashita T, Honda M, Kaneko S. Hepatology. 69 2 653-665 2019/02/01
- Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano K, Masaki N, Sugauchi F, Izumi N, Tokunaga K, Mizokami M Nat Genet. 41 10 1105-9 2009/10/01
- Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation. Fujinaga H, Sakai Y, Yamashita T, Arai K, Terashima T, Komura T, Seki A, Kawaguchi K, Nasti A, Yoshida K, Wada T, Yamamoto K, Kume K, Hasegawa T, Takata T, Honda M, Kaneko S. Int J Radiat Biol. Epub ahead of print 2018/12/17
- Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis Diagnosis of NASH using serum fatty acid. Yamada K, Mizukoshi E, Seike T, Horii R, Terashima T, Iida N, Kitahara M, Sunagozaka H, Arai K, Yamashita T, Honda M, Takamura T, Harada K, Kaneko S. J Gastroenterol Hepatol. Epub ahead of print 2019/03/12
- Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis. Satoh S, Onomura D, Ueda Y, Dansako H, Honda M, Kaneko S, Kato N. Biochem J. 476 1 137-149 2019/01/15
- POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33. Hitomi Y, ほか85名、50番目 Sci Rep. 9 1 102 2019/01/14
- Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models. Sakai Y, Miyazawa M, Komura T, Yamada T, Nasti A, Yoshida K, Takabatake H, Yamato M, Yamashita T, Yamashita T, Mizukoshi E, Okuzono M, Ho TTB, Kawaguchi K, Wada T, Honda M, Kaneko S. Cancer Sci. 110 3 903-912 2019/03/01
- Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation. Wang Z, Kawaguchi K, Honda M, Hashimoto S, Shirasaki T, Okada H, Orita N, Shimakami T, Yamashita T, Sakai Y, Mizukoshi E, Murakami S, Kaneko S. Sci Rep. 9 1 1621 2019/02/07
- The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication. Shirasaki T, Honda M, Yamashita T, Nio K, Shimakami T, Shimizu R, Nakasyo S, Murai K, Shirasaki N, Okada H, Sakai Y, Sato T, Suzuki T, Yoshioka K, Kaneko S. Sci Rep. 8 1 13143 2018/09/03
- Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood. Komura T, Yano M, Miyake A, Takabatake H, Miyazawa M, Ogawa N, Seki A, Honda M, Wada T, Matsui S, Kaneko S, Sakai Y. Can J Gastroenterol Hepatol. 2018 7436205 2018/06/11
- Distinct notch signaling expression patterns between nucleoside and nucleotide analogues treatment for hepatitis B virus infection. Wang Z, Kawaguchi K, Honda M, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Biochem Biophys Res Commun. 501 3 682-687 2018/06/27
- Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma. Sawai H, Nishida N, Khor SS, Honda M, Sugiyama M, Baba N, Yamada K, Sawada N, Tsugane S, Koike K, Kondo Y, Yatsuhashi H, Nagaoka S, Taketomi A, Fukai M, Kurosaki M, Izumi N, Kang JH, Murata K, Hino K, Nishina S, Matsumoto A, Tanaka E, Sakamoto N, Ogawa K, Yamamoto K, Tamori A, Yokosuka O, Kanda T, Sakaida I, Itoh Y, Eguchi Y, Oeda S, Mochida S, Yuen MF, Seto WK, Poovorawan Y, Posuwan N, Mizokami M, Tokunaga K. Sci Rep. 8 1 7958 2018/05/21
- Immune responses of human T lymphocytes to novel hepatitis B virus-derived peptides. Yamamiya D, Mizukoshi E, Kaji K, Terashima T, Kitahara M, Yamashita T, Arai K, Fushimi K, Honda M, Kaneko S. PLoS One. 13 6 e0198264 2018/06/01
- Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B. Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S. J Gastroenterol. 53 6 740-751 2018/06/01
- Unexpected Replication Boost by Simeprevir for Simeprevir-resistant Variants in Genotype 1a Hepatitis C Virus. Murai K, Shimakami T, Welsch C, Shirasaki T, Liu F, Kitabayashi J, Tanaka S, Funaki M, Omura H, Nishikawa T, Suminyadorj A, Honda M, Kaneko S. Antimicrob Agents Chemother 62 7 e02601-17 2018/06/26
- Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection. Murata K, Asano M, Matsumoto A, Sugiyama M, Nishida N, Tanaka E, Inoue T, Sakamoto M, Enomoto N, Shirasaki T, Honda M, Kaneko S, Gatanaga H, Oka S, Kawamura YI, Dohi T, Shuno Y, Yano H, Mizokami M. Gut 67 362-371 2018/01/01
- Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease. Yamada K, Mizukoshi E, Seike T, Horii R, Kitahara M, Sunagozaka H, Arai K, Yamashita T, Honda M, Kaneko S. PLoS One 13 e0191026 2018/01/01
- Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro. Murai K, Shirasaki T, Honda M, Shimizu R, Shimakami T, Nakasho S, Shirasaki N, Okada H, Sakai Y, Yamashita T, Kaneko S. Int J Mol Sci 19 108 2017/04/01
- The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells. Nasti A, Sakai Y, Seki A, Buffa GB, Komura T, Mochida H, Yamato M, Yoshida K, Ho TTB, Takamura M, Usui S, Wada T, Honda M, Kaneko S. Eur J Immunol 47 2163-2174 2017/04/01
- Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study. Hayashi T, Yamashita T, Terashima T, Suda T, Okada H, Asahina Y, Hayashi T, Hara Y, Nio K, Sunagozaka H, Takatori H, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. BMC Cancer 17 870 2017/04/01
- Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo. Funaki M, Kitabayashi J, Shimakami T, Nagata N, Sakai Y, Takegoshi K, Okada H, Murai K, Shirasaki T, Oyama T, Yamashita T, Ota T, Takuwa Y, Honda M, Kaneko S. Sci Rep 7 16978 2017/04/01
- Reactivation of Hepatitis B Virus from an isolated Anti-HBc positive patient after eradication of Hepatitis C Virus with Direct-acting Antiviral Agents. Suda T, Shimakami T, Shirasaki T, Yamashita T, Mizukoshi E, Honda M, Kaneko S. J Hepatol 67 1108-1111 2017/04/01
- Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma. Komura T, Takabatake H, Harada K, Yamato M, Miyazawa M, Yoshida K, Honda M, Wada T, Kitagawa H, Ohta T, Kaneko S, Sakai Y. Cancer Sci 108 2122-2129 2017/04/01
- Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma. Hayashi T, Yamashita T, Okada H, Nio K, Hara Y, Nomura Y, Hayashi T, Asahina Y, Yoshida M, Oishi N, Sunagozaka H, Takatori H, Honda M, Kaneko S. Cancer Cell Int 17 97 2017/04/01
- The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis. Enomoto H, Tao L, Eguchi R, Sato A, Honda M, Kaneko S, Iwata Y, Nishikawa H, Imanishi H, Iijima H, Tsujimura T, Nishiguchi S. Sci Rep 7 12189 2017/04/01
- Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes. Honda M, Shirasaki T, Shimakami T, Sakai A, Horii R, Arai K, Yamashita T, Sakai Y, Yamashita T, Okada H, Murai K, Nakamura M, Mizukoshi E and Kaneko S. Hepatology 59 3 828-38 2014/03/01
- Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma. Yamashita T, Kitao A, Matsui O, Hayashi T, Nio K, Kondo M, Ohno N, Miyati T, Okada H, Yamashita T, Mizukoshi M, Honda M, Nakanuma Y, Takamura H, Ohta T, Nakamoto Y, Yamamoto M, Takayama T, Arii S, Wang XW, Kaneko S. Hepatology 60 5 1674-85 2014/11/01
- Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway. Shirasaki T, Honda M, Shimakami T, Murai K, Shiomoto T, Okada H, Takabatake R, Tokumaru A, Sakai Y, Yamashita T, Lemon SM, Murakami S, Kaneko S. Hepatology 60 5 1519-30 2014/11/01
- ER stress induced impaired TLR signaling and macrophage differentiation of human monocytes. Komura T, Sakai Y, Honda M, Takamura T, Wada T, Kaneko S. Cell Immunol. 282 1 44-52 2013/04/24
- Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling. Ueda T, Honda M, Horimoto K, Aburatani S, Saito S, Yamashita T, Sakai Y, Nakamura M, Takatori H, Sunagozaka H, Kaneko S. Genomics. 101 4 238-48 2013/04/01
- Association of Interleukin 28B genotype and hepatocellular carcinoma recurrence in patients with chronic hepatitis C. Hodo Y, Honda M, Tanaka A, Nomura Y, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Sakai A, Sasaki M, Nakanuma Y, Moriyama M, Kaneko S. Clin Cancer Res. 19 7 1827-37 2013/04/01
- Altered gene expression in T-cell receptor signalling in peripheral blood leucocytes in acute coronary syndrome predicts secondary coronary events. Takashima S, Usui S, Kurokawa K, Kitano T, Kato T, Murai H, Furusho H, Oda H, Maruyama M, Nagata Y, Usuda K, Kubota K, Takeshita Y, Sakai Y, Honda M, Kaneko S, Takamura M. Open Heart. 3 1 e000400 2016/06/30
- Response to chemotherapy improved hepatic reserve for patients with hepatocellular carcinoma and Child-Pugh B cirrhosis. Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Cancer Sci. 107 9 1263-9 2016/09/01
- Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model. Takegoshi K, Honda M, Okada H, Takabatake R, Matsuzawa-Nagata N, Campbell JS, Nishikawa M, Shimakami T, Shirasaki T, Sakai Y, Yamashita T, Takamura T, Tanaka T, Kaneko S. Oncotarget. Epub ahead of print 2017/02/13
- Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems. Liu F, Shimakami T, Murai K, Shirasaki T, Funaki M, Honda M, Murakami S, Yi M, Tang H, Kaneko S. Sci Rep. 6 30939 2016/04/03
- P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma. Terashima T, Mizukoshi E, Arai K, Yamashita T, Yoshida M, Ota H, Onishi I, Kayahara M, Ohtsubo K, Kagaya T, Honda M, Kaneko S. Cancer Immunol Immunother. 63 5 479-89 2014/05/01
- TSU-68 Ameliorates Hepatocellular Carcinoma Growth by Inhibiting Microenvironmental Platelet-derived Growth Factor Signaling. Hara Y, Yamashita T, Oishi N, Nio K, Hayashi T, Nomura Y, Yoshida M, Hayashi T, Hashiba T, Asahina Y, Kondo M, Okada H, Sunagozaka H, Honda M, Kaneko S. Anticancer Res. 35 3 1423-31 2015/03/01
- Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. Selitsky SR, Dinh TA, Toth CL, Kurtz CL, Honda M, Struck BR, Kaneko S, Vickers KC, Lemon SM, Sethupathy P. MBio. 6 6 e01500-15 2015/12/08
- Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice. Okada H, Honda M, Campbell JS, Takegoshi K, Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S. Cancer Sci. 106 9 1143-52 2015/09/01
- Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma. Honda M, Yamashita T, Yamashita T, Arai K, Sakai Y, Sakai A, Nakamura M, Mizukoshi E, Kaneko S. 15 13 191 2013/04/01
- Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma. Nio K, Yamashita T, Okada H, Kondo M, Hayashi T, Hara Y, Nomura Y, Zeng SS, Yoshida M, Hayashi T, Sunagozaka H, Oishi N, Honda M, Kaneko S. J Hepatol. 63 5 1164-72 2015/11/01
- Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis. Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S. Liver Int. 35 6 1773 2015/06/01
- Inflammatory features of pancreatic cancer highlighted by monocytes/macrophages and CD4+ T cells with clinical impact. Komura T, Sakai Y, Harada K, Kawaguchi K, Takabatake H, Kitagawa H, Wada T, Honda M, Ohta T, Nakanuma Y, Kaneko S. Cancer Sci. 106 6 672-86 2015/06/01
- Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy. Terashima T, Yamashita T, Iida N, Yamashita T, Nakagawa H, Arai K, Kitamura K, Kagaya T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Hepatol Res. 45 9 949-59 2015/09/01
- Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice. Okada H, Honda M, Campbell JS, Takegoshi K, Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S. Cancer Sci. 106 9 1143-52 2015/06/01
- Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma. Yamashita T, Horii R, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. BMC Cancer. 16 1 338 2016/05/31
- Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants. Yamane D, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM. Nucleic Acids Res. Epub ahead of print 2017/01/12
- Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B. Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S. J Gastroenterol. Epub ahead of print 2017/08/01
- De Novo Emergence of Mesenchymal Stem-Like CD105+ Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma. Nomura Y, Yamashita T, Oishi N, Nio K, Hayashi T, Yoshida M, Hayashi T, Hashiba T, Asahina Y, Okada H, Sunagozaka H, Takatori H, Honda M, Kaneko S. Transl Oncol 10 2 184-189 2017/04/01
- Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma. Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Liver Cancer 6 236-249 2017/04/01
- Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer. Kawaguchi K, Honda M, Yamashita T, Okada H, Shirasaki T, Nishikawa M, Nio K, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Am J Pathol. 186 8 2055-67 2016/06/14
- Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C. Iio E, Matsuura K, Nishida N, Maekawa S, Enomoto N, Nakagawa M, Sakamoto N, Yatsuhashi H, Kurosaki M, Izumi N, Hiasa Y, Masaki N, Ide T, Hino K, Tamori A, Honda M, Kaneko S, Mochida S, Nomura H, Nishiguchi S, Okuse C, Itoh Y, Yoshiji H, Sakaida I, Yamamoto K, Watanabe H, Hige S, Matsumoto A, Tanaka E, Tokunaga K, Tanaka Y. Hum Genet. 134 3 279-89 2015/03/01
- Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population. Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Nakamura H, Tanaka A, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Abe M, Nakao K, Yamagiwa S, Kaneko S, Honda M, Umemura T, Ichida T, Seike M, Sakisaka S, Harada M, Yokosuka O, Ueno Y, Senju M, Kanda T, Shibata H, Himoto T, Murata K, Miyake Y, Ebinuma H, Taniai M, Joshita S, Nikami T, Ota H, Kouno H, Kouno H, Nakamuta M, Fukushima N, Kohjima M, Komatsu T, Komeda T, Ohara Y, Muro T, Yamashita T, Yoshizawa K, Nakamura Y, Shimada M, Hirashima N, Sugi K, Ario K, Takesaki E, Naganuma A, Mano H, Yamashita H, Matsushita K, Yamauchi K, Makita F, Nishimura H, Furuta K, Takahashi N, Kikuchi M, Masaki N, Tanaka T, Tamura S, Mori A, Yagi S, Shirabe K, Komori A, Migita K, Ito M, Nagaoka S, Abiru S, Yatsuhashi H, Yasunami M, Shimoda S, Harada K, Egawa H, Maehara Y, Uemoto S, Kokudo N, Takikawa H, Ishibashi H, Chayama K, Mizokami M, Nagasaki M, Tokunaga K, Nakamura M. Hum Mol Genet. Epub ahead of print 2017/01/05
- Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma. Honda M, Shirasaki T, Terashima T, Kawaguchi K, Nakamura M, Oishi N, Wang X, Shimakami T, Okada H, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. J Infect Dis. 213 7 1096-106 2016/04/01
- Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis. Nishida N, Ohashi J, Khor SS, Sugiyama M, Tsuchiura T, Sawai H, Hino K, Honda M, Kaneko S, Yatsuhashi H, Yokosuka O, Koike K, Kurosaki M, Izumi N, Korenaga M, Kang JH, Tanaka E, Taketomi A, Eguchi Y, Sakamoto N, Yamamoto K, Tamori A, Sakaida I, Hige S, Itoh Y, Mochida S, Mita E, Takikawa Y, Ide T, Hiasa Y, Kojima H, Yamamoto K, Nakamura M, Saji H, Sasazuki T, Kanto T, Tokunaga K, Mizokami M. Sci Rep. 6 24767 2016/04/19
- Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B. Wang X, Oishi N, Shimakami T, Yamashita T, Honda M, Murakami S, Kaneko S. World J Gastroenterol. 23 3252-3261 2017/04/01
- MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells. Shirasaki T, Honda M, Shimakami T, Horii R, Yamashita T, Sakai Y, Sakai A, Okada H, Watanabe R, Murakami S, Yi M, Lemon SM, Kaneko S. J Virol. 87 9 5270-86 2013/05/01
- A Novel mTOR Inhibitor; Anthracimycin for the Treatment of Human Hepatocellular Carcinoma Hayashi T, Yamashita T, Okada H, Oishi N, Sunagozaka H, Nio K, Hayashi T, Hara Y, Asahina Y, Yoshida M, Hashiba T, Suda T, Shirasaki T, Igarashi Y, Miyanouchi K, Yamashita T, Honda M, Kaneko S. Anticancer Res 37 7 3397-3403 2017/07/01
- Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib. Terashima T, Yamashita T, Takata N, Nakagawa H, Toyama T, Arai K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Hepatol Res. 46 7 650-6 2016/06/01
- Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. Matsuura K, Sawai H, Ikeo K, Ogawa S, Iio E, Isogawa M, Shimada N, Komori A, Toyoda H, Kumada T, Namisaki T, Yoshiji H, Sakamoto N, Nakagawa M, Asahina Y, Kurosaki M, Izumi N, Enomoto N, Kusakabe A, Kajiwara E, Itoh Y, Ide T, Tamori A, Matsubara M, Kawada N, Shirabe K, Tomita E, Honda M, Kaneko S, Nishina S, Suetsugu A, Hiasa Y, Watanabe H, Genda T, Sakaida I, Nishiguchi S, Takaguchi K, Tanaka E, Sugihara J, Shimada M, Kondo Y, Kawai Y, Kojima K, Nagasaki M, Tokunaga K, Tanaka Y; Japanese Genome-Wide Association Study Group for Viral Hepatitis. Gastroenterology. Epub ahead of print 2017/02/02
- Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α. Satoh S, Mori K, Onomura D, Ueda Y, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N. Hepatol Commun 1 550-563 2017/04/01
- Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet. Okada H, Takabatake R, *Honda M, Takegoshi K, Yamashita T, Nakamura M, Shirasaki T, Sakai Y, Shimakami T, Nagata N, Takamura T, Tanaka T, Kaneko S. Oncotarget 8 39978-39993 2017/04/01
- Post-progression survival and progression-free survival in patients with advanced hepatocellular carcinoma treated by sorafenib. Terashima T, Yamashita T, Takata N, Nakagawa H, Toyama T, Arai K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S. Hepatol Res. 2015/10/01
- HBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics. Kawaguchi K, Honda M, Kaneko S. Transl Cancer Res 5 S2 S216-220 2016/04/01
- Molecular Mechanism Underlying the Suppression of CPB2 Expression Caused by Persistent Hepatitis C Virus RNA Replication. Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N. Acta Med Okayama. 70 2 75-88 2016/04/01
- Identification of blood biomarkers of aging by transcript profiling of whole blood Nakamura, Seiji; Kawai, Kozo; Takeshita, Yumie; Honda, Masao; Takamura, Toshinari; Kaneko, Shuichi; Matoba, Ryo; Matsubara, Kenichi Biochemical and Biophysical Research Communications 418 2 313-318 2012/02/10
- GENES EXPRESSION OF WHOLE BLOOD CELLS REFLECT THE DISTINCT PATHOPHYSIOLOGICAL FEATURES OF TYPE C CIRRHOSIS AND HEPATOCELLULAR CARCINOMA PATIENTS Sakai, Yoshio;Honda, Masao;Komura, Takuya;Tatsumi, Isamu;Miyazaki, Yoshitaka;Tanno, Hiroshi;Wada, Takashi;Kaneko, Shuichi HEPATOLOGY 54 0 784A-784A 2011
- Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update Kaneko, Shuichi; Furuse, Junji; Kudo, Masatoshi; Ikeda, Kenji; Honda, Masao; Nakamoto, Yasunari; Onchi, Morikazu; Shiota, Goshi; Yokosuka, Osamu; Sakaida, Isao; Takehara, Tetsuo; Ueno, Yoshiyuki; Hiroishi, Kazumasa; Nishiguchi, Shuhei; Moriwaki, Hisataka; Yamamoto, Kazuhide; Sata, Michio; Obi, Shuntaro I.; Miyayama, Shiro; Imai, Yukinori Hepatology Research 42 6 523-542 2012/06/01
- Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma He, Danning; Liu, Zhiping; Honda, Masao; Kaneko, Shuichi; Chen, Luonan Journal of Molecular Cell Biology 4 3 140-152 2012/06/01
- Feasibility and efficacy of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma after sorafenib Terashima, Takeshi; Yamashita, Tatsuya; Arai, Kuniaki; Sunagozaka, Hajime; Kitahara, Masaaki; Nakagawa, Hidetoshi; Kagaya, Takashi; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi Hepatology Research 44 12 1179-1185 2014/01/01
- Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients Shindo, Hiroko; Maekawa, Shinya; Komase, Kazuki; Sueki, Ryota; Miura, Mika; Kadokura, Makoto; Shindo, Kuniaki; Amemiya, Fumitake; Kitamura, Takatoshi; Nakayama, Yasuhiro; Inoue, Taisuke; Sakamoto, Minoru; Okada, Shunichi; Asahina, Yasuhiro; Izumi, Namiki; Honda, Masao; Kaneko, Shuichi; Enomoto, Nobuyuki Hepatology International 6 2 482-490 2012/04/01
- Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean Nishida, Nao; Sawai, Hiromi; Matsuura, Kentaro; Sugiyama, Masaya; Ahn, Sanghoon; Park, Junyong; Hige, Shuhei; Kang, Jonghon; Suzuki, Kazuyuki; Kurosaki, Masayuki; Asahina, Yasuhiro; Mochida, Satoshi; Watanabe, Masaaki; Tanaka, Eiji; Honda, Masao; Kaneko, Shuichi; Orito, Etsuro; Itoh, Yoshito; Mita, Eiji; Tamori, Akihiro; Murawaki, Yoshikazu; Hiasa, Yoichi; Sakaida, Isao; Korenaga, Masaaki; Hino, Keisuke; Ide, Tatsuya; Kawashima, Minae; Mawatari, Yoriko; Sageshima, Megumi; Ogasawara, Yuko; Koike, Asako; Izumi, Namiki; Han, Kwanghyub; Tanaka, Yasuhito; Tokunaga, Katsushi; Mizokami, Masashi PLoS ONE 7 6 2012/06/21
- Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population Nakamura, Minoru; Nishida, Nao; Kawashima, Minae; Aiba, Yoshihiro; Tanaka, Atsushi; Yasunami, Michio; Nakamura, Hitomi; Komori, Atsumasai; Nakamuta, Makoto; Zeniya, Mikio; Hashimoto, Etsuko; Ohira, Hiromasa; Yamamoto, Kazuhide; Onji, Morikazu Morikazu; Kaneko, Shuichi; Honda, Masao; Yamagiwa, Satoshi; Nakao, Kazuhiko; Ichida, Takafumi; Takikawa, Hajime; Seike, Masataka; Umemura, Takeji; Ueno, Yoshiyuki; Sakisaka, Shotaro; Kikuchi, Kentaro; Ebinuma, Hirotoshi; Yamashiki, Noriyo; Tamura, Sumihito; Sugawara, Yasuhiko; Mori, Akira; Yagi, Shintaro; Shirabe, Ken; Taketomi, Akinobu; Arai, Kuniaki; Monoe, Kyoko; Ichikawa, Tatsuki; Taniai, Makiko; Miyake, Yasuhiro; Kumagi, Teru; Abe, Masanori; Yoshizawa, Kaname; Joshita, Satoru; Shimoda, Shinji; Honda, Koichi; Takahashi, Hiroki; Hirano, Katsuji; Takeyama, Yasuaki; Harada, Kenichi; Migita, Kiyoshi; Ito, Masahiro; Yatsuhashi, Hiroshi; Fukushima, Nobuyoshi; Ota, Hajime; Komatsu, Tatsuji; Saoshiro, Takeo; Ishida, Jinya; Kouno, Hirotsugu; Kouno, Hirotaka; Yagura, Michiyasu; Kobayashi, Masakazu; Muro, Toyokichi; Masaki, Naohiko; Hirata, Keiichi; Watanabe, Yukio; Nakamura, Yoko; Shimada, Masaaki; Hirashima, Noboru; Komeda, Toshiki; Sugi, Kazuhiro; Koga, Michiaki; Ario, Keisuke; Takesaki, Eiichi; Maehara, Yoshihiko; Uemoto, Shinji; Kokudo, Norihiro; Tsubouchi, Hirohito; Mizokami, Masashi; Nakanuma, Yasuni; Tokunaga, Katsushi; Ishibashi, Hiromi American Journal of Human Genetics 91 4 721-728 2012/10/05
- Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma Miyahara, Koji; Nouso, Kazuhiro; Morimoto, Youichi; Takeuchi, Yasuto; Hagihara, Hiroaki; Kuwaki, Kenji; Onishi, Hideki; Ikeda, Fusao; Miyake, Yasuhiro; Nakamura, Shinichiro; Shiraha, Hidenori; Takaki, Akinobu; Honda, Masao; Kaneko, Shuichi; Sato, Takahisa; Sato, Shuichi; Obi, Shuntaro I.; Iwadou, Shouta; Kobayashi, Yoshiyuki; Takaguchi, Kouichi; Kariyama, Kazuya; Takuma, Yoshitaka; Takabatake, Hiroyuki; Yamamoto, K.; Yamamoto, Kazuhide; Morimoro, Yuki; Takuma, Yoshitaka; Takabatake, Hiroyuki; Fujioka, Shinichi; Osawa, Toshiya; Kariyama, Kazuya; Toshimori, Junichi; Kobashi, Haruhiko; Miyatake, Hirokazu; Uematsu, Shuji; Okamoto, Ryoichi; Araki, Yasuyuki; Tatsukawa, Masafumi; Yabushita, Kazuhisa; Shimoe, Toshinari; Sakaguchi, Kohsaku; Sakata, Tatsuro; Kaneyoshi, Toshihiko; Miyashita, Manabi; Makino, Yasuhiro; Moriya, Akio; Ando, Masaharu; Baba, Nobuyuki; Seno, Tomonori; Nagano, Takuya; Matsumoto, Eiji; Takayama, Hiroki British Journal of Cancer 109 8 2072-2078 2013/10/15
- GLYCOGENE EXPRESSION ANALYSIS IN THE LIVER OF CHRONIC HEPATITIS B AND C COMPLICATED WITH HCC ENABLES TO IDENTIFY INFECTION SPECIFIC AND TUMOR SPECIFIC GLYCOGENES USEFUL FOR CLINICAL BIOMARKER Shigeyama, Isamu;Honda, Masao;Ueda, Teruyuki;Shirasaki, Takayoshi;Yamashita, Taro;Sakai, Yoshio;Kaneko, Shuichi HEPATOLOGY 54 0 1303A-1303A 2011
- Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis. Komura T, Mizukoshi E, Kita Y, Sakurai M, Takata Y, Arai K, Yamashita T, Ohta T, Shimizu K, Nakamoto Y, Honda M, Takamura T, Kaneko S AMERICAN JOURNAL OF GASTROENTEROLOGY 102 9 1939-46 2007/09
- Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C Tanaka, Yasuhito; Kurosaki, Masayuki; Nishida, Nao; Sugiyama, Masaya; Matsuura, Kentaro; Sakamoto, Naoya; Enomoto, Nobuyuki; Yatsuhashi, Hiroshi; Nishiguchi, Shuhei; Hino, Keisuke; Hige, Shuhei; Itoh, Yoshito; Tanaka, Eiji; Mochida, Satoshi; Honda, Masao; Hiasa, Yoichi; Koike, Asako; Sugauchi, Fuminaka; Kaneko, Shuichi; Izumi, Namiki; Tokunaga, Katsushi; Mizokami, Masashi Human Molecular Genetics 20 17 3507-3516 2011/09/01
- Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C. Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Kaneko S HEPATOLOGY 44 5 1122-38 2006/11
- Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Matsuzawa N, Takamura T, Kurita S, Misu H, Ota T, Ando H, Yokoyama M, Honda M, Zen Y, Nakanuma Y, Miyamoto K, Kaneko S HEPATOLOGY 46 5 1392-403 2007/11
- Altered hepatic gene expression profiles associated with myocardial ischemia. Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, Horimoto K, Takamura M. Circ Cardiovasc Genet. 3 1 68-77 2010/02
- 3 ' SUPPLEMENTARY BASE-PAIR INTERACTIONS OF MIR-122 WITH HEPATITIS C VIRUS RNA CONTRIBUTE TO STABILIZATION OF THE HCV RNA GENOME Shimakami, Tetsuro;Jangra, Rohit K.;Welsch, Christoph;Yamane, Daisuke;Hensley, Lucinda;Honda, Masao;Kaneko, Shuichi;Lemon, Stanley HEPATOLOGY 54 0 405A-405A 2011
- alpha-FETOPROTEIN-PRODUCING HEPATOMA CELLS HAVE INCREASED JAGGED1 GENE COPY NUMBERS AND THEIR GROWTH CAN BE SUPPRESSED BY GAMMA SECRETASE INHIBITOR Kawaguchi, Kazunori;Honda, Masao;Yamashita, Taro;Takatori, Hajime;Ueda, Teruyuki;Kanno, Masataka;Nishikawa, Masashi;Kaneko, Shuichi HEPATOLOGY 54 0 1290A-1290A 2011
- HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2/B1, ASSOCIATED WITH HUMAN TELOMERASE REVERSE TRANSCRIPTASE, IS IDENTIFIED AS A POTENTIAL BIOMARKER FOR HEPATOCELLULAR CARCINOMA BASED ON PROTEOMICS ANALYSIS Mizuno, Hideki;Honda, Masao;Shirasaki, Takayoshi;Yamashita, Taro;Kaneko, Shuichi HEPATOLOGY 54 0 1307A-1307A 2011
- IMPAIRED IFN SIGNALING IN CHRONIC HEPATITIS C WITH ADVANCED FIBROSIS STAGE TROUGH TGF-beta SIGNALING PATHWAY Tokumaru, Norihiro;Honda, Masao;Shirasaki, Takayoshi;Shimakami, Tetsuro;Kawaguchi, Kazunori;Kaneko, Shuichi HEPATOLOGY 54 0 1331A-1331A 2011
- HCV INFECTIVITY VARIATION AND HVR1 QUASISPECIES SELECTION ARE ASSOCIATED WITH THE DISTRIBUTION OF HCV E1/E2 SYNONYMOUS MUTATIONS Kawaguchi, Kazunori;Honda, Masao;Shirasaki, Takayoshi;Emerson, Suzanne U.;Purcell, Robert H.;Kaneko, Shuichi HEPATOLOGY 54 0 1352A-1353A 2011
- A phase I study of vaccination with human telomerase reverse transcriptase-derived peptide in patients with hepatocellular carcinoma Mizukoshi, Eishiro;Yamashita, Tatsuya;Arai, Kuniaki;Sunagozaka, Hajime;Yamashita, Taro;Honda, Masao;Kaneko, Shuichi HEPATOLOGY 56 0 490A-490A 2012
- ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C. Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M HEPATOLOGY RESEARCH 40 11 1063-1071 2010/11
- Involvement of chromatin remodeling enzyme CHD4 in chemoresistance of EpCAM plus hepatic cancer stem cells Nio, Kouki;Yamashita, Taro;Honda, Masao;Okada, Hikari;Kaneko, Shuichi HEPATOLOGY 56 0 278A-278A 2012
- A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S Cell Metab. 12 5 483-95 2010/11
- Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C. Honda M, Nakamura M, Tateno M, Sakai A, Shimakami T, Shirasaki T, Yamashita T, Arai K, Yamashita T, Sakai Y, Kaneko S JOURNAL OF HEPATOLOGY 53 5 817-26 2010/11
- EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. amashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, Jia H, Ye Q, Qin LX, Wauthier E, Reid LM, Minato H, Kaneko S, Tang ZY, Wang XW. GASTROENTEROLOGY 136 3 1012-24 2009/03
- Efficacy and safety of hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma Yamashita, Tatsuya;Terashima, Takeshi;Arai, Kuniaki;Sunagozaka, Hajime;Yamashita, Taro;Mizukoshi, Eishiro;Sakai, Akito;Honda, Masao;Kaneko, Shuichi HEPATOLOGY 56 0 471A-471A 2012
- Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development Okada, Hikari;Honda, Masao;Campbell, Jean S.;Sakai, Yoshio;Yamashita, Taro;Shirasaki, Takayoshi;Tanaka, Takuji;Fausto, Nelson;Kaneko, Shuichi HEPATOLOGY 56 0 614A-614A 2012
- Acyclic retinoid and branched chain amino acids improve liver fibrosis and reduce tumorigenesis in mice fed an atherogenic high-fat diet Takegoshi, Kai;Honda, Masao;Okada, Hikari;Kondo, Mitsumasa;Yamashita, Taro;Matsuzawa, Naoto;Takamura, Toshinari;Tanaka, Takuji;Kaneko, Shuichi HEPATOLOGY 56 0 770A-770A 2012
- Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection Yamashita, Taro;Honda, Masao;Kaneko, Shuichi JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 26 6 960-964 2011
- Inhibition of Hepatitis C Virus Replication by Acyclic Retinoid Shimakami, Tetsuro;Honda, Masao;Shirasaki, Takayoshi;Lemon, Stanley;Kaneko, Shuichi HEPATOLOGY 56 0 713A-714A 2012
- MicroRNA expression profiling in serum and liver of patients with chronic hepatitis C Horii, Rika;Honda, Masao;Sakai, Akito;Nakamura, Mikiko;Kaneko, Shuichi HEPATOLOGY 56 0 692A-692A 2012
- Impaired infiltration of immune regulatory cells into liver lobules of chronic hepatitis C patients with interferon-resistant IL28B genotype Honda, Masao;Sakai, Akito;Shirasaki, Takayoshi;Nakamura, Mikiko;Yamashita, Tatsuya;Arai, Kuniaki;Shimakami, Tetsuro;Sakai, Yoshio;Yamashita, Taro;Mizukoshi, Eishiro;Kaneko, Shuichi HEPATOLOGY 56 0 708A-708A 2012
- Therapeutic effect of adipose derived mesenchymal stem cell to murine NASH liver cirrhosis inactivating Kupffer/Macrophage and helper T cell Seki, Akihiro;Sakai, Yoshio;Komura, Takuya;Higashimoto, Mami;Fujinaga, Haruo;Honda, Masao;Wada, Takashi;Takamura, Toshinari;Ochiya, Takahiro;Kaneko, Shuichi HEPATOLOGY 56 0 1101A-1101A 2012
- Gene expression profile of primary hepatocytes and the differential innate antiviral response of IFN-alpha and IL28B Shirasaki, Takayoshi;Honda, Masao;Shimakami, Tetsuro;Okada, Hikari;Lemon, Stanley;Murakami, Seishi;Kaneko, Shuichi HEPATOLOGY 56 0 705A-705A 2012
- The Evolution of Diverse Cancer Stem Cells in Human Liver Cancer Yamashita, Taro;Honda, Masao;Nakamoto, Yasunari;Nio, Kouki;Hara, Yasumasa;Zeng, Sha Sha;Hayashi, Takehiro;Yamashita, Tatsuya;Mizukoshi, Eishiro;Wang, Xin W.;Kaneko, Shuichi HEPATOLOGY 56 0 443A-443A 2012
- Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon. Shimakami T, Honda M, Kusakawa T, Murata T, Shimotohno K, Kaneko S, Murakami S JOURNAL OF VIROLOGY 80 7 3332-40 2006/04
- Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma. Nishino R, Honda M, Yamashita T, Takatori H, Minato H, Zen Y, Sasaki M, Takamura H, Horimoto K, Ohta T, Nakanuma Y, Kaneko S JOURNAL OF HEPATOLOGY 49 2 207-16 2008/08
- Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning. Teramoto R, Minagawa H, Honda M, Miyazaki K, Tabuse Y, Kamijo K, Ueda T, Kaneko S BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1784 5 764-72 2008/05
- Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma. Minagawa H, Honda M, Miyazaki K, Tabuse Y, Teramoto R, Yamashita T, Nishino R, Takatori H, Ueda T, Kamijo K, Kaneko S BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 366 1 186-92 2008/02
- Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy. Tateno M, Honda M, Kawamura T, Honda H, Kaneko S JOURNAL OF INFECTIOUS DISEASES 195 2 255-67 2007/01
- Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients. Takamura T, Misu H, Matsuzawa-Nagata N, Sakurai M, Ota T, Shimizu A, Kurita S, Takeshita Y, Ando H, Honda M, Kaneko S OBESITY RESEARCH 16 12 2601-9 2008/12
- The development and clinical features of splenic aneurysm associated with liver cirrhosis. Sunagozaka H, Tsuji H, Mizukoshi E, Arai K, Kagaya T, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S Liver Int. 26 3 291-7 2006/04
- Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells. Oishi N, Shilagardi K, Nakamoto Y, Honda M, Kaneko S, Murakami S Cancer Sci. 98 10 1540-8 2007/10
- Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C Selitsky, Sara R.;Baran-Gale, Jeanette;Honda, Masao;Yamane, Daisuke;Masaki, Takahiro;Fannin, Emily E.;Guerra, Bernadette;Shirasaki, Takayoshi;Shimakami, Tetsuro;Kaneko, Shuichi;Lanford, Robert E.;Lemon, Stanley M.;Sethupathy, Praveen SCIENTIFIC REPORTS 5 7675 2015/01/01
- Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+ T-cell suppression. Higashimoto M, Sakai Y, Takamura M, Usui S, Nasti A, Yoshida K, Seki A, Komura T, Honda M, Wada T, Furuichi K, Ochiya T, Kaneko S. Eur J Immunol. 43 11 2956-68 2013/11/01
- The acyclic retinoid Peretinoin inhibits hepatitis C virus replication and infectious virus release in vitro. Shimakami, Tetsuro; Honda, Masao; Shirasaki, Takayoshi; Takabatake, Riuta; Liu, Fanwei; Murai, Kazuhisa; Shiomoto, Takayuki; Funaki, Masaya; Yamane, Daisuke; Murakami, Seishi; Lemon, Stanley M.; Kaneko, Shuichi Scientific reports 4 2014/01/01
- The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: A randomised controlled trial Takeshita, Yumie; Takamura, Toshinari; Honda, Masao; Kita, Yuki; Zen, Yoh; Kato, Kenichiro; Misu, Hirofumi; Ota, Tsuguhito; Nakamura, Mikiko; Yamada, Kazutoshi; Sunagozaka, Hajime; Arai, Kuniaki; Yamashita, Tatsuya; Mizukoshi, Eishiro; Kaneko, Shuichi Diabetologia 57 5 878-890 2014/01/01
- Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma Sunagozaka, Hajime; Honda, Masao; Yamashita, Taro; Nishino, Ryuhei; Takatori, Hajime; Arai, Kuniaki; Yamashita, Tatsuya; Sakai, Yoshio; Kaneko, Shuichi International Journal of Cancer 129 7 1576-1585 2011/10/01
- Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma Yamashita, Taro; Honda, Masao; Nakamoto, Yasunari; Baba, Masayo; Nio, Kouki; Hara, Yasumasa; Zeng, Shasha; Hayashi, Takehiro; Kondo, Mitsumasa; Takatori, Hajime; Yamashita, Tatsuya; Mizukoshi, Eishiro; Ikeda, Hiroko; Zen, Yoh; Takamura, Hiroyuki; Wang, Xin Wei; Kaneko, Shuichi Hepatology 57 4 1484-1497 2013/04/01
- Expression of chondroitin-glucuronate C5-epimerase and cellular immune responses in patients with hepatocellular carcinoma Mizukoshi, Eishiro; Fushimi, Kazumi; Arai, Kuniaki; Yamashita, Tatsuya; Honda, Masao; Kaneko, Shuichi Liver International 32 10 1516-1526 2012/11/01
- Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy Terashima, Takeshi; Yamashita, Tatsuya; Iida, Noriho; Yamashita, Taro; Nakagawa, Hidetoshi; Arai, Kuniaki; Kitamura, Kazuya; Kagaya, Takashi; Sakai, Yoshio; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi Hepatology Research 2014/01/01
- A case of Crohn's disease that showed hepatic portal venous gas and perforation of small intestine at the time of balloon-assisted enteroscopy Yano, Masaaki; Takatori, Hajime; Kitamura, Kazuya; Kagaya, Takashi; Mizukoshi, Eishiro; Sakai, Akito; Honda, Masao; Tsukada, Tomoya; Fushida, Sachio; Kaneko, Shuichi Gastroenterological Endoscopy 56 9 3358-3364 2014/01/01
- [A case report of S-1 monotherapy for advanced hepatocellular carcinoma]. Yamashita, Tatsuya; Arai, Kuniaki; Terashima, Takeshi; Sunagozaka, Hajime; Shimakami, Tetsuro; Yamashita, Taro; Mizukoshi, Eishiro; Sakai, Akito; Honda, Masao; Kaneko, Shuichi Gan to kagaku ryoho. Cancer & chemotherapy 39 9 1435-1437 2012/09/01
- Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma. Ura S, Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Sunakozaka H, Sakai Y, Horimoto K, Kaneko S HEPATOLOGY 49 4 1098-112 2009/04
- Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes. Takamura T, Honda M, Sakai Y, Ando H, Shimizu A, Ota T, Sakurai M, Misu H, Kurita S, Matsuzawa-Nagata N, Uchikata M, Nakamura S, Matoba R, Tanino M, Matsubara K, Kaneko S BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 361 2 379-84 2007/09
- Amplification of Jagged1 copy number in tumor DNA is associated with poor survival from hepatocellular carcinoma Kawaguchi, Kazunori;Honda, Masao;Yamashita, Taro;Takatori, Hajime;Ueda, Teruyuki;Mizuno, Hideki;Nishikawa, Masashi;Kaneko, Shuichi HEPATOLOGY 56 0 618A-618A 2012
- Diagnostic benefits of adrenocortical scintigraphy in hepatic adrenal rest tumor Ishida, Kosuke; Horii, Rika; Yamashita, Tatsuya; Arai, Kuniaki; Yamashita, Taro; Kagaya, Takashi; Sakai, Yoshio; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi Journal of Japanese Society of Gastroenterology 111 10 2004-2012 2014/01/01
- Prognosis of autoimmune hepatitis showing acute presentation Yamamoto, Kazuhide; Miyake, Yasuhiro; Ohira, Hiromasa; Suzuki, Yoshiyuki; Zeniya, Mikio; Onji, Morikazu Morikazu; Tsubouchi, Hirohito; Yoshizawa, Kaname; Morizane, Toshio; Hibi, Toshifumi; Aoyagi, Yutaka; Nakanuma, Yasuni; Hirohara, Junko; Takikawa, Hajime; Ishibashi, Hiromi; Shimoda, Shinji; Sakisaka, Shotaro; Nakamuta, Makoto; Matsuzaki, Yasushi; Saibara, Toshiji; Ueno, Yoshiyuki; Miyakawa, Hiroshi; Kokudo, Norihiro; Egawa, Hiroto; Maehara, Yoshihiko; Mochida, Satoshi; Sakaida, Isao; Fujisawa, Tomoo; Suzuki, Kazuyuki; Inoue, Kazuaki; Ichida, Takafumi; Yokosuka, Osamu; Fukui, Hiroshi; Moriwaki, Hisataka; Mori, Mitsuru; Mori, Toshiyuki; Nagino, Masato; Sata, Naohiro; Tazuma, Susumu; Yasaka, Takahiro; Tsuyuguchi, Toshio; Shoda, Junichi; Honda, Masao; Yamaue, Hiroki; Unno, Michiaki; Hayashi, Norio Hepatology Research 43 6 630-638 2013/06/01
- Autoantibody status and histological variables influence biochemical response to treatment and long-term outcomes in Japanese patients with primary biliary cirrhosis Nakamura, Minoru; Kondo, Hisayoshi; Tanaka, Atsushi; Komori, Atsumasa; Ito, Masahiro; Yamamoto, Kazuhide; Ohira, Hiromasa; Zeniya, Mikio; Hashimoto, Etsuko; Honda, Masao; Kaneko, Shuichi; Ueno, Yoshiyuki; Kikuchi, Kentaro; Shimoda, Shinji; Harada, Kenichi; Arai, Kuniaki; Miyake, Yasuhiro; Abe, Masanori; Taniai, Makiko; Saibara, Toshiji; Sakisaka, Shotaro; Takikawa, Hajime; Onji, Morikazu Morikazu; Tsubouchi, Hirohito; Nakanuma, Yasuni; Ishibashi, Hiromi Hepatology Research 45 8 846-55 2015/01/01
- ASSOCIATION OF INTERLEUKIN 28B GENOTYPE AND HEPATOCELLULAR CARCINOMA RECURRENCE IN PATIENTS WITH CHRONIC HEPATITIS C Hodo, Yuji;Honda, Masao;Kaneko, Shuichi HEPATOLOGY 54 0 1363A-1363A 2011
- DISTINCT LIVER CANCER STEM CELLS DEFINED BY EPCAM AND CD90 IN HUMAN HEPATOCELLULAR CARCINOMA Yamashita, Taro;Honda, Masao;Nakamoto, Yasunari;Mizukoshi, Eishiro;Yamashita, Tatsuya;Arai, Kuniaki;Nio, Kouki;Hara, Yasumasa;Wang, Xin W.;Kaneko, Shuichi HEPATOLOGY 54 0 449A-449A 2011
- Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity. Matsuzawa-Nagata N, Takamura T, Ando H, Nakamura S, Kurita S, Misu H, Ota T, Yokoyama M, Honda M, Miyamoto K, Kaneko S METABOLISM-CLINICAL AND EXPERIMENTAL 57 8 1071-7 2008/08
- CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes. Komura T, Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S DIABETES 59 3 634-43 2010/03
- Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma. Hodo Y, Hashimoto S, Honda M, Yamashita T, Suzuki Y, Sugano S, Kaneko S, Matsushima K GENOMICS 95 4 217-23 2010/04
- La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication. Shirasaki T, Honda M, Mizuno H, Shimakami T, Okada H, Sakai Y, Murakami S, Wakita T, Kaneko S JOURNAL OF INFECTIOUS DISEASES 202 1 75-85 2010/07
- Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients. Sakai Y, Honda M, Fujinaga H, Tatsumi I, Mizukoshi E, Nakamoto Y, Kaneko S CANCER RESEARCH 68 24 10267-79 2008/12
- Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma. Yamashita T, Honda M, Takatori H, Nishino R, Minato H, Takamura H, Ohta T, Kaneko S. JOURNAL OF HEPATOLOGY 50 1 100-10 2009/01
- dUTP pyrophosphatase expression correlates with a poor prognosis in hepatocellular carcinoma. Takatori H, Yamashita T, Honda M, Nishino R, Arai K, Yamashita T, Takamura H, Ohta T, Zen Y, Kaneko S Liver Int. 30 3 438-46 2010/03
- POSITIVE ANTI-GP210 ANTIBODIES IS A SIGNIFICANT RISK FACTOR FOR BILE DUCT LOSS, HEPATITIS AND POOR BIOCHEMICAL RESPONSE TO URSODEOXYCHOLIC ACID TREATMENT THAT LEAD TO MORE SEVERE PROGRESSION IN JAPANESE PATIENTS WITH PRIMARY BILIARY CIRRHOSIS Nakamura, Minoru;Ito, Masahiro;Kondo, Hisayoshi;Yamamoto, Kazuhide;Ohira, Hiromasa;Zeniya, Mikio;Tanaka, Atsushi;Hashimoto, Etsuko;Honda, Masao;Kaneko, Shuichi;Ueno, Yoshiyuki;Kikuchi, Kentaro;Shimoda, Shinji;Komori, Atsumasa;Harada, Kenichi;Sakisaka, Shotaro;Takikawa, Hajime;Onji, Morikazu;Onishi, Saburo;Tsubouchi, Hirohito;Nakanuma, Yasuni;Ishibashi, Hiromi HEPATOLOGY 54 0 1208A-1209A 2011
- A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma Okusaka, Takuji; Kasugai, Hiroshi; Ishii, Hiroshi; Kudo, Masatoshi; Sata, Michio; Tanaka, Katsuaki; Shioyama, Yasukazu; Chayama, Kazuaki; Kumada, Hiromitsu; Yoshikawa, Masaharu; Seki, Toshihito; Saito, Hidetsugu; Hayashi, Naoaki; Shiratori, Keiko; Okita, Kiwamu; Sakaida, Isao; Honda, Masao; Kusumoto, Yukio; Tsutsumi, Takuya; Sakata, Kenji Investigational New Drugs 30 5 2015-2025 2012/10/01
- Pure red cell aplasia associated with concomitant use of mycophenolate mofetil and ribavirin in post-transplant recurrent hepatitis C. Hodo Y, Tsuji K, Mizukoshi E, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S TRANSPLANT INTERNATIONAL 19 2 170-1 2006/02
- Endothelial to mesenchymal transition via transforming growth factor-beta1/Smad activation is associated with portal venous stenosis in idiopathic portal hypertension. Kitao A, Sato Y, Sawada-Kitamura S, Harada K, Sasaki M, Morikawa H, Shiomi S, Honda M, Matsui O, Nakanuma Y AMERICAN JOURNAL OF PATHOLOGY 175 2 616-26 2009/08
- Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. Yamashita T, Honda M, Nio K, Nakamoto Y, Yamashita T, Takamura H, Tani T, Zen Y, Kaneko S CANCER RESEARCH 70 11 4687-97 2010/06
- microRNA-122 Abundance in Hepatocellular Carcinoma and Non-Tumor Liver Tissue from Japanese Patients with Persistent HCV versus HBV Infection Spaniel, Carolyn; Honda, Masao; Selitsky, Sara R.; Yamane, Daisuke; Shimakami, Tetsuro; Kaneko, Shuichi; Lanford, Robert E.; Lemon, Stanley M. PLoS ONE 8 10 2013/10/09
- Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors Kurosaki, Masayuki;Tanaka, Yasuhito;Nishida, Nao;Sakamoto, Naoya;Enomoto, Nobuyuki;Honda, Masao;Sugiyama, Masaya;Matsuura, Kentaro;Sugauchi, Fuminaka;Asahina, Yasuhiro;Nakagawa, Mina;Watanabe, Mamoru;Sakamoto, Minoru;Maekawa, Shinya;Sakai, Akito;Kaneko, Shuichi;Ito, Kiyoaki;Masaki, Naohiko;Tokunaga, Katsushi;Izumi, Namiki;Mizokami, Masashi JOURNAL OF HEPATOLOGY 54 3 439-448 2011
- Comparative Analysis of Various Tumor-Associated Antigen-Specific T-Cell Responses in Patients with Hepatocellular Carcinoma Mizukoshi, Eishiro;Nakamoto, Yasunari;Arai, Kuniaki;Yamashita, Tatsuya;Sakai, Akito;Sakai, Yoshio;Kagaya, Takashi;Yamashita, Taro;Honda, Masao;Kaneko, Shuichi HEPATOLOGY 53 4 1206-1216 2011
- Differential gene expression profiling in blood from patients with digestive system cancers. Honda M, Sakai Y, Yamashita T, Yamashita T, Sakai A, Mizukoshi E, Nakamoto Y, Tatsumi I, Miyazaki Y, Tanno H, Kaneko S; Hokuriku Liver Study Group BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 400 1 7-15 2010/09
- The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma Zeng, Shasha; Yamashita, Taro; Kondo, Mitsumasa; Nio, Kouki; Hayashi, Takehiro; Hara, Yasumasa; Nomura, Yoshimoto; Yoshida, Mariko; Hayashi, Tomoyuki; Oishi, Naoki; Ikeda, Hiroko; Honda, Masao; Kaneko, Shuichi Journal of Hepatology 60 1 127-134 2014/01/01
- MICRORNA-27A REGULATES LIPID METABOLISM AND INHIBITS HCV REPLICATION IN HUMAN HEPATOMA CELL LINE Shirasaki, Takayoshi;Honda, Masao;Tokumaru, Norihiro;Shimakami, Tetsuro;Kawaguchi, Kazunori;Mizuno, Hideki;Shigeyama, Isamu;Yi, MinKyung;Lemon, Stanley;Murakami, Seishi;Kaneko, Shuichi HEPATOLOGY 54 0 1345A-1345A 2011
- MALNUTRITION IMPAIRS INTERFERON SIGNALING THROUGH MTOR AND FOXO PATHWAYS IN PATIENTS WITH CHRONIC HEPATITIS C Honda, Masao;Takehana, Kenji;Sakai, Akito;Shirasaki, Takayoshi;Yamashita, Tatsuya;Kawaguchi, Kazunori;Arai, Kuniaki;Shimakami, Tetsuro;Sakai, Yoshio;Yamashita, Taro;Mizukoshi, Eishiro;Nishitani, Shinobu;Tagata, Yusuke;Kaneko, Shuichi HEPATOLOGY 54 0 843A-844A 2011
- No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations Sawai, Hiromi; Nishida, Nao; Mbarek, Hamdi; Matsuda, Koichi; Mawatari, Yoriko; Yamaoka, Megumi; Hige, Shuhei; Kang, Jonghon; Abe, Koichi; Mochida, Satoshi; Watanabe, Masaaki; Kurosaki, Masayuki; Asahina, Yasuhiro; Izumi, Namiki; Honda, Masao; Kaneko, Shuichi; Tanaka, Eiji; Matsuura, Kentaro; Itoh, Yoshito; Mita, Eiji; Korenaga, Masaaki; Hino, Keisuke; Murawaki, Yoshikazu; Hiasa, Yoichi; Ide, Tatsuya; Ito, Kiyoaki; Sugiyama, Masaya; Ahn, Sanghoon; Han, Kwanghyub; Park, Junyong; Yuen, Man Fung; Nakamura, Yusuke; Tanaka, Yasuhito; Mizokami, Masashi; Tokunaga, Katsushi BMC Medical Genetics 13 2012/06/19
- Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: Possible link to serum anti-endothelial cell antibodies Sato, Yasunori; Ren, Xiangshan; Harada, Kenichi; Sasaki, Motoko; Morikawa, Hiroyasu; Shiomi, Susumu; Honda, Masao; Kaneko, Shuichi; Nakanuma, Yasuni Clinical and Experimental Immunology 167 3 532-542 2012/03/01
- Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon. Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K FEBS LETTERS 581 10 1983-7 2007/05
- Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma. Mizukoshi E, Honda M, Arai K, Yamashita T, Nakamoto Y, Kaneko S JOURNAL OF HEPATOLOGY 49 6 946-54 2008/12
- Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study. Yamashita T, Arai K, Sakai A, Mizukoshi E, Sakai Y, Kagaya T, Nakamoto Y, Honda M, Wada T, Yokoyama H, Kaneko S HEPATOLOGY RESEARCH 36 3 167-75 2006/11
- New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia Nishida, Nao; Sawai, Hiromi; Kashiwase, Koichi; Minami, Mutsuhiko; Sugiyama, Masaya; Seto, Wai-Kay; Yuen, Manfung; Posuwan, Nawarat; Poovorawan, Yong; Ahn, Sanghoon; Han, Kwanghyub; Matsuura, Kentaro; Tanaka, Yasuhito; Kurosaki, Masayuki; Asahina, Yasuhiro; Izumi, Namiki; Kang, Jonghon; Hige, Shuhei; Yamamoto, Tatsuya Ide Kazuhide; Sakaida, Isao; Murawaki, Yoshikazu; Itoh, Yoshito; Tamori, Akihiro; Orito, Etsuro; Hiasa, Yoichi; Honda, Masao; Kaneko, Shuichi; Mita, Eiji; Suzuki, Kazuyuki; Hino, Keisuke; Tanaka, Eiji; Mochida, Satoshi; Watanabe, Masaaki; Eguchi, Yuichiro; Masaki, Naohiko; Murata, Kazumoto; Korenaga, Masaaki; Mawatari, Yoriko; Ohashi, Jun; Kawashima, Minae; Tokunaga, Katsushi; Mizokami, Masashi PLoS ONE 9 2 e86449 2014/02/10
- Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes. Misu H, Takamura T, Matsuzawa N, Shimizu A, Ota T, Sakurai M, Ando H, Arai K, Yamashita T, Honda M, Yamashita T, Kaneko S DIABETOLOGIA 50 2 268-77 2007/02
- Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model. Seki A, Sakai Y, Komura T, Nasti A, Yoshida K, Higashimoto M, Honda M, Usui S, Takamura M, Takamura T, Ochiya T, Furuichi K, Wada T, Kaneko S. Hepatology 58 3 1133-42 2013/09/01
- Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes Takeshita, Yumie; Takamura, Toshinari; Kita, Yuki; Ando, Hitoshi; Ueda, Teruyuki; Kato, Kenichiro; Misu, Hirofumi; Sunagozaka, Hajime; Sakai, Yoshio; Yamashita, Tatsuya; Mizukoshi, Eishiro; Honda, Masao; Kaneko, Shuichi Metabolism: Clinical and Experimental 61 10 1388-1394 2012/10/01
- Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis Yamada, Kazutoshi;Mizukoshi, Eishiro;Sunagozaka, Hajime;Arai, Kuniaki;Yamashita, Tatsuya;Takeshita, Yumie;Misu, Hirofumi;Takamura, Toshinari;Kitamura, Seiko;Zen, Yoh;Nakanuma, Yasuni;Honda, Masao;Kaneko, Shuichi LIVER INTERNATIONAL 35 2 582-590 2015/01/01
Conference Presentations
- Surrogacy of time to progression for overall survival in advanced hepatocellular carcinoma treated with systemic therapy: A systematic review and eta-analysis of randomized controlled trials.(conference：ASCO-GI 2018)(2018/01/19)
- NASH患者における肝線維化と血清AKR1B10との関連(2018/04/19)
- Characteristics and Functional Regulation of Dendritic Cells in Hepatitis B Patients(2018/11/09)
- Immune response to tumor-associated antigens and immune vell profiles in NASH-related hepatocellular carcinoma(2018/11/12)
- Adipose tissue derived stromal/stem cells alleviated hepatic fibrosis development induced by IL17-mediated stellate cell activation in NASH mice.(2018/11/11)
- Levocarnitine improves Liver Histology and the Development of Hepatocellular Carcinoma in the Atherogenic High-Fat Diet Nash-HCC Mouse Model(2018/11/11)
- Inactivation of transcriptional repressor capicua confers chemoresistance to sorafenib in hepatocellular carcinoma(2018/11/12)
- Mint3 is a novel molecular target expressed in well-differentiated AFP-negative HCC for prevention of cancer progression.(2018/11/10)
- A Liver-Derived Secretory Protein, LECT2, Enhances the Innate Immune Response and Suppresses RIG-I Mediated Virus Infection(2018/11/10)
- A liver-derived secretory protein, LECT2, restores the impaired plasmacytoid dendritic cells function by HBV and protects hepatocytes against HBV infection(conference：2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses)(2018/10/05)
- Dendritic cell functions and characteristic gene expression profiles in hepatitis B virus-infected patients(2017/10/31)
- Identification of novel HLA-A24-restricted endogenous CTL epitopes derived from HBV genotype C(conference：AASLD2017)(2017/10/22)
- Inhibitory effect of acyclic retinoid on hepatitis B virus replication(conference：AASLD2017)(2017/10/22)
- A liver-derived secretory protein, LECT2, activates plasmacytoid dendritic cells and protects hepatocytes from HBV infection(conference：AASLD2017)(2017/10/22)
- Promoted liver fibrosis and malignant phenotype in HCV/PDGF-C transgenic mouse are accompanied by abnormal expression of the glycolysis-related gene pyruvate kinase M(conference：AASLD2017)(2017/10/23)
- Immunomodulation of aggressive liver cancer by EpCAM+ cancer stem cells thorough the activation of CCL20-CCR6 axis(conference：AASLD2017)(2017/10/23)
- The utility of the serum C16:1n7/C16:0 ratio as a diagnostic marker of non-alcoholic steatohepatitis(conference：AASLD2017)(2017/10/23)
- Notch signaling inhibition is associated with degradation of intrahepatic HBV by ITCH in an ubiquitin-dependent manner(conference：AASLD2017)(2017/10/22)
- Nucleos(t)ide analogues and interferon affect intranuclear HBV genome in vitro via Notch signaling modification,independent of the ubiquitin-proteasome system(conference：AASLD2017)(2017/10/22)
- IFN-λ3 induces dendritic cell maturation independent of type I IFN(conference：AASLD2017)(2017/10/21)
- mRNA for selenoprotein P, a hepatokine, binds RIG-I protein and inhibits the RIG-I-mediated type I interferon response(2017/10/21)
- Regulation of Hepatitis C Virus Infection by Long Non-Coding RNA(2017/10/21)
- MicroRNA-10a is associated with the impaired liver functions in patients with advanced stage of chronic hepatitis C(2017/10/21)
- Osteopontin regulates IFN signaling and HCV replication in cancer stem cells(2017/10/21)
- Serum Cytokine Profiles Predict Survival Benefits in Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib: a Retrospective Cohort Study(conference：AASLD2017)(2017/10/20)
- Genome-wide methylation analysis identified a new intrahepatic angiogenesis marker associated with induction of tumorigenesis after successful eradication of HCV(2017/10/21)
- Unexpected Enhancement of Replication Capacity by Simeprevir for Simeprevir-Resistant Variants in Genotype 1a Hepatitis C Virus(2017/10/21)
- (2017/06/09)
- Strategy for the Treatment for Chronic Hepatitis C Patients in Japan(conference：2nd international symposium on viral Hepatitis)(2015/06/23)
- HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma.(conference：AASLD2015)(2015/11/16)
- HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma(conference：International Meeting on Molecular Biology of Hepatitis B Viruses 2015)(2015/10/05)
- 動脈硬化高脂肪食マウスモデルにおける非環式レチノイドの脂肪化・肝発癌抑制効果の検討(2015/12/03)
- Treatment of HCV-infected patients in Japan and an Experimental Model of HCV Infection(2014/12/10)
- Impaired IFN signaling in chronic hepatitis C patients with advanced fibrosis via the TGF-β signaling pathway(2014/09/07)
- C型慢性肝炎IL28Bマイナー遺伝子多型例における肝内ISG高値と治療抵抗性の機序(2013/06/06)
- Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes. パラレルセッション（口演）(conference：AASLD2013)(2013/11/05)
- Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes.(conference：HCV2013)(2013/10/08)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
○IFNL4の臨床応用
○HBV
Grant-in-Aid for Scientific Research
○「Nucleotide analogue製剤のサイトカイン誘導を利用してB型肝炎のドラックフリーを目指す治療法の開発および創薬に関する研究」(2018-2020)
○「NAFLD/NASH肝組織リン酸化活性プロファイリングと新規治療標的分子の同定」(2018-2020)
○「DOCK12ノックダウンによりcccDNA排除の新規抗HBV治療応用への基礎研究」(2018-2020)
○「肝線維化に伴うリモデリングを正常化する新規治療法の開発」(2017-2019)
○「C型肝炎ウイルス排除後の病態、生命予後、QOLに関する包括的研究」(2017-2019)
○「肝硬変における炎症細胞社会の解明」(2017-2021)
○「C型肝炎における慢性肝炎から発がんに至る病態の解明と制御に関する研究」(2016-2018)
○「C型肝炎の新たな治療関連因子及び治癒後の病態進展・改善に関連する宿主因子等の同定を目指したゲノムワイド研究」(2016-2018)
○「IFNλ4 の機能的役割の解明及び新規診断法・治療法の開発」(2016-2018)
○「Ｃ型肝炎における慢性肝炎から発がんに至る病態の解明と制御に関する研究」(2016-2018)
○「包括的１細胞遺伝子発現解析を用いたB型肝炎ウイルス感染機構の解明」(2016-)
○「肝炎ウイルス治療後の肝発癌機序とバイオマーカーの同定に関する研究」(2015-2017)
○「内分泌器官としての肝臓病学の確立」(2014-2018)
○「ゲノム網羅的解析によるＢ型肝炎ウイルス感染の病態関連遺伝子の同定と新規診断法の開発」(2014-2016)
○「肝炎ウイルス複製を支持する新規肝癌由来培養細胞の樹立」(2014-2015)
○「Ｃ型肝炎の新規診断法や新規治療法を開発するためのゲノムワイド関連解析の手法を用いた宿主因子の解析に関する研究」(2013-2015)
○「Ｃ型慢性肝炎治療成績の向上と肝発癌阻止を目指した分子基盤の確立」(2012-2014)
○「過栄養状態の肝臓が産生するタンパクと生活習慣病の関連」(2011-2013)
○「ウイルス性肝炎に対する応答性を規定する宿主因子も含めた情報のデータベース構築・治療応用に関する研究」(2010-2012)
○「肝がんの新規治療法に関する研究」(2009-2011)
○「C型慢性肝炎インターフェロン療法の応答・不応答に関わる宿主遺伝子の探索」(2009-2011)
○「肝炎ウイルスの培養系を用いた新規肝炎治療法の開発」(2007-2009)
○「末梢血単核球の発現プロファイルと肝病態」(2007-2008)
○「テーラーメイド治療を目指した肝炎ウイルスデータベース構築に関する研究」(2007-2009)
○「C型肝炎ウイルス増殖に関わる宿主因子の同定とその肝病態における役割」(2005-2006)
○「C型肝炎ウイルス増殖に関わる宿主因子の同定」(2002-2003)
○「Ｃ型肝炎ウイルスの蛋白翻訳開始機構に関する検討」(1998-1999)
○「インターフェロンによるＣ型肝炎ウイルス蛋白翻訳抑制機構の解明」(2000-2001)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Introduction to Practical Medicine(2018)
○Experimental Course of Clinical Physiology II(2018)
○Laboratory of Serology and Immunology(2018)
○Presentation and Debate (Freshman Seminar II)(2018)
○Microbiology Genetics(2018)
○Introduction of Clinical Medicine(2018)
○Introduction of Clinical Medicine(2018)
○Research Project(2018)
○Lecture and Practice of Virology(2018)
○Pathogenic Microbiology 2(2018)
○Pathophysiology 1(2018)
○Presentation and Debate (Freshman Seminar II)(2017)
○Introduction of Clinical Medicine(2017)
○Pathogenic Microbiology 2(2017)
○Lecture and Practice of Virology(2017)
○Presentation and Debate (Freshman Seminar II)(2017)
○Experimental Course of Clinical Physiology(2017)
○Introduction of Clinical Medicine(2017)
○Introduction to Practical Medicine(2017)
○Introduction to Practical Medicine(2017)
○Laboratory of Serology and Immunology(2017)
○Microbiology Genetics(2017)
Classes (Graduate Schools)
○Molecular Biology of Tumor: Lecture(2018)
○Molecular Biology of Tumor: Seminar(2018)
○Laboratory Oncology: Lecture(2018)
○Laboratory Oncology: Seminar(2018)
○Laboratory Oncology: Research(2018)
○Advanced Laboratory Oncology: Research(2018)
○Introduction to Medicine(2018)
○An Introduction to Medical Laboratory Sciences:Lec(2018)
○Fostering the independence of researchers(2018)
○omics(2017)
○Molecular Biology of Tumor: Lecture(2017)
○An Introduction to Medical Laboratory Sciences:Lec(2017)
○Molecular Biology of Tumor: Seminar(2017)
○Laboratory Oncology: Research(2017)
○Introduction to Medicine(2017)
○Laboratory Oncology: Lecture(2017)
○Laboratory Oncology: Seminar(2017)
○Advanced Laboratory Oncology: Research(2017)
○Fostering the independence of researchers(2017)