Assistant Professor TSUNO, Yusuke
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Division of Medical Sciences, Graduate School of Medical Science
Division of Medicine, Graduate School of Medical Science
School of Medicine, College of Medical, Pharmaceutical and Health Sciences
Laboratory
Department of Integrative Neurophysiology TEL:076-265-2173 FAX:076-234-4224
Academic Background
【Academic background(Doctoral/Master's Degree)】
The University of Tokyo, Department of Physiology, Graduate School of Medicine Doctor 2009 Completed
The University of Tokyo, Department of Physiology, Graduate School of Medicine Master 2005 Completed
【Academic background(Bachelor's Degree)】
The University of Tokyo, Laboratory of Neurobiophysics, Faculty of Pharmaceutical Sciences 2003
【Degree】
Ph.D.
Career
Kanazawa University, Graduate School of Medical Science Department of Integrative Neurophysiology Assistant Professor(2018/04-)
University of Utah Department of Neurobiology and Anatomy Postdoctoral Fellow(2015/09-2018/03)
Boston University Department of Psychological and Brain Sciences Postdoctoral Associate(2010/01-2015/08)
Boston University Department of Biology Research Associate(2009/04-2009/12)
Year & Month of Birth
Academic Society
The Japan Neuroscience Society
Society for Neuroscience
Japanese Society for Chronobiology
The Physiological Society of Japan
Award
○Healthy Longevity Global Grand Challenge Catalyst Award(2020/10)
○Travel Grant for Attending Lindau Meetings(2011/06)
Specialities
Neurophysiology/General neuroscience
Speciality Keywords
Electrophysiology, Imaging, Learning, Memory, Sleep, Olfactory System, Circadian Rhythm, Acetylcholine
Research Themes
Books
Papers
- Circadian rhythm mechanism in the suprachiasmatic nucleus and its relation to the olfactory system. Yusuke Tsuno, Michihiro Mieda Front. Neural Circuits 18 1385908 2024/03/25
- In vivo recording of the circadian calcium rhythm in Prokineticin 2 neurons of the suprachiasmatic nucleus Kaito Onodera,Yusuke Tsuno,Yuichi Hiraoka,Kohichi Tanaka,Takashi Maejima,Michihiro Mieda Scientific Reports 13 1 16974 2023/10/09
- In vivo recording of suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in circadian pacesetting Yusuke Tsuno,Yubo Peng,Shin-ichi Horike,Mohan Wang,Ayako Matsui,Kanato Yamagata,Mizuki Sugiyama,Takahiro J. Nakamura,Takiko Daikoku,Takashi Maejima,Michihiro Mieda PLOS Biology 21 8 e3002281 2023/08/29
- Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons. Md Tarikul Islam,Florian Rumpf,Yusuke Tsuno,Shota Kodani,Takeshi Sakurai,Ayako Matsui,Takashi Maejima,Michihiro Mieda Current Biology 32 18 3871 2022/07/29
- Cell Type-Specific Genetic Manipulation and Impaired Circadian Rhythms in Vip tTA Knock-In Mice. Yubo Peng,Yusuke Tsuno,Ayako Matsui,Yuichi Hiraoka,Kohichi Tanaka,Shin-Ichi Horike,Takiko Daikoku,Michihiro Mieda Frontiers in Physiology 13 895633 2022/05/03
- Wireless Photometry Prototype for Tri-Color Excitation and Multi-Region Recording Aatreya Chakravarti,Amin Hazrati Marangalou,Ian Matthew Costanzo,Devdip Sen,Mirco Sciulli,Yusuke Tsuno,Ulkuhan Guler Micromachines 13 5 727 2022/04/30
- GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior. Takashi Maejima, Yusuke Tsuno, Shota Miyazaki, Yousuke Tsuneoka, Emi Hasegawa, Md Tarikul Islam, Ryosuke Enoki, Takahiro J. Nakamura, Michihiro Mieda Proceedings of the National Academy of Sciences 118 e2010168118 2021/02/09
- Inhalation Frequency Controls Reformatting of Mitral/Tufted Cell Odor Representations in the Olfactory Bulb. Díaz-Quesada M,Youngstrom IA,Tsuno Y,Hansen KR,Economo MN,Wachowiak M The Journal of Neuroscience 38 9 2189 2018/02
- Post-Inhibitory Rebound Spikes in Rat Medial Entorhinal Layer II/III Principal Cells: In Vivo, In Vitro, and Computational Modeling Characterization Michele Ferrante,Christopher F. Shay,Yusuke Tsuno,G. William Chapman,Michael E. Hasselmo Cerebral Cortex 27 3 2111 2017/03
- Cell-Type-Specific Modulation of Sensory Responses in Olfactory Bulb Circuits by Serotonergic Projections from the Raphe Nuclei Daniela Brunert,Yusuke Tsuno,Markus Rothermel,Michael T. Shipley,Matt Wachowiak The Journal of Neuroscience 36 25 6820 2016/06
- Rebound spiking properties of mouse medial entorhinal cortex neurons in vivo Yusuke Tsuno,George W. Chapman,Michael E. Hasselmo European Journal of Neuroscience 42 11 2974 2015/12
- In vivo cholinergic modulation of the cellular properties of medial entorhinal cortex neurons Yusuke Tsuno,Nathan W. Schultheiss,Michael E. Hasselmo The Journal of Physiology 591 10 2611 2013/05
- Testing the Sorption Hypothesis in Olfaction: A Limited Role for Sniff Strength in Shaping Primary Odor Representations During Behavior Tristan Cenier,John P. McGann,Yusuke Tsuno,Justus V. Verhagen,Matt Wachowiak The Journal of Neuroscience 33 1 79 2013/01
- Effects of acetylcholine on neuronal properties in entorhinal cortex James G. Heys,Nathan W. Schultheiss,Christopher F. Shay,Yusuke Tsuno,Michael E. Hasselmo Frontiers in Behavioral Neuroscience 6 32 2012/07
- Behavioral state-dependent changes in the information processing mode in the olfactory system Yusuke Tsuno,Kensaku Mori Communicative and Integrative Biology 2 4 362 2009/07
- Dendrodendritic synapses and functional compartmentalization in the olfactory bulb Kensaku Mori,Hideyuki Matsumoto,Yusuke Tsuno,Kei M. Igarashi Annals of the New York Academy of Sciences 1170 255 2009
- Behavioral state regulation of dendrodendritic synaptic inhibition in the olfactory bulb Yusuke Tsuno,Hideki Kashiwadani,Kensaku Mori The Journal of Neuroscience 28 37 9227 2008/09
Conference Presentations
- In vivo fiber photometry to reveal AVP neuronal function of the suprachiasmatic nucleus via cell-type specific labeling strategy(conference：The 19th Environmental Physiology Pre-Congress)(2025/03/16)
- Suprachiasmatic nucleus AVP neurons alter VIP neuronal Ca2+ activity and locomotor activity rhythms(conference：NEURO2024, The 47th Annual Meeting of the Japan Neuroscience Society)(2024/07/26)
- In vivo analysis of suprachiasmatic nucleus circadian rhythm using neuronal cell type-specific knockout mice(conference：Joint Congress of the 45th Annual Meeting of Japanese Society of Sleep Research, the 30th Annual Meeting of Japanese Society for Chronobiology)(2023/09/15)
- In vivo recording of the suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in the circadian pacesetting(conference：The 17th Environmental Physiology Pre-Congress)(2023/03/13)
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○Grant-in-Aid for Scientific Research(C)「Elucidation of circadian rhythm mechanisms using cell type-specific photometry」(2023-2025)
○Grant-in-Aid for Scientific Research(C)「In vivo analysis of suprachiasmatic nucleus AVP neurons using multiple type sensors」(2020-2022)
○Grant-in-Aid for Research Activity start-up「Cell-type specific calcium imaging of suprachiasmatic nucleus with fiber photometry」(2018-2019)
Competitive research funding,Contribution
○"Cholinergic input in accelerated versus slow cognitive decline upon aging" Interstellar Initiative Beyond (Japan Agency for Medical Research and Development)(2022-2022)
○"Cholinergic input in fast versus slow cognitive decline upon aging" Healthy Longevity Global Grand Challenge, Catalyst Award (Japan Agency for Medical Research and Development)(2020-2021)
Collaborative research,Consignment study
Classes (Bachelors)
○Neurophysiology(2024)
○Neurophysiology(2023)
○Neurophysiology(2022)
○Neurophysiology(2021)
○Neurophysiology(2020)
○Neurophysiology(2019)
○Neurophysiology(2018)
Classes (Graduate Schools)
○The Function of the Human Body(2024)
○The Function of the Human Body(2023)
○The Function of the Human Body(2022)
○Molecular Neuroscience and Integrative Physiology(2021)
○The Function of the Human Body(2021)
○Molecular Neuroscience and Integrative Physiology(2020)
○The Function of the Human Body(2020)
○Molecular Neuroscience and Integrative Physiology(2019)
○The Function of the Human Body(2019)
○Molecular Neuroscience and Integrative Physiology(2018)