本文へジャンプ

研究者情報

データ更新日:2022年05月21日

藤原 浩 (ふじわら ひろし) 教授 Fujiwara Hiroshi

所属組織・役職等

医薬保健研究域 医学系 金沢大学医薬保健研究域医学系 分子移植学
主任教授

教育分野

所属研究室等

学歴

【出身大学】
京都大学  医学科 1983/03 卒業
【取得学位】
論医博

職歴

生年月

所属学会

学内委員会委員等

○医学博士・修士課程委員会(2016-2021)
○病院運営委員会 委員(2016-2021)
○臨床倫理委員会 委員(2016-2019)
○学生支援員会 委員(2016-2018)

受賞学術賞

専門分野

専門分野キーワード

研究課題

著書

論文

  • Laminin suppresses progesterone production by human luteinizing granulosa cells via interaction with integrin alpha(6)beta(1) JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 82巻 7号 2122頁 1997/07 査読有 研究論文(学術雑誌)
  • A mouse monoclonal antibody, s2n8, detects a 140 kda protein on the surface of human endometrial stromal cells and decidual cells Molecular Human Reproduction 1巻 3号 147頁 1995 査読有 研究論文(学術雑誌)
  • CYTOKINE MODULATION OF PROGESTERONE AND ESTRADIOL SECRETION IN CULTURES OF LUTEINIZED HUMAN GRANULOSA-CELLS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 75巻 1号 254頁 1992/07 査読有 研究論文(学術雑誌)
  • EXPRESSION AND LOCALIZATION OF AMINOPEPTIDASE-N, NEUTRAL ENDOPEPTIDASE, AND DIPEPTIDYL PEPTIDASE-IV IN THE HUMAN PLACENTA AND FETAL MEMBRANES AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 170巻 4号 1163頁 1994/04 査読有 研究論文(学術雑誌)
  • Dual control of ovarian function through endocrine and immune systems IXTH WORLD CONGRESS ON IN VITRO FERTILIZATION AND ASSISTED REPRODUCTION 3頁 1995 査読有 研究論文(プロシーディング)

全て表示

  • A PORCINE HOMOLOG OF HUMAN INTEGRIN ALPHA-6 IS A DIFFERENTIATION ANTIGEN OF GRANULOSA-CELLS BIOLOGY OF REPRODUCTION 53巻 2号 407頁 1995/08 査読有 研究論文(学術雑誌)
  • Granulosa cells express integrin α6: Possible involvement of integrin α6 in folliculogenesis Hormone Research in Paediatrics 46巻 24頁 1996 査読有 研究論文(学術雑誌)
  • Spontaneous conception and intrauterine pregnancy in a symptomatic missed abortion of ectopic pregnancy conceived in the previous cycle HUMAN REPRODUCTION 11巻 6号 1347頁 1996/06 査読有 研究論文(学術雑誌)
  • An aminopeptidase inhibitor, bestatin, enhances gonadotrophin-stimulated ovulation in mice HUMAN REPRODUCTION 11巻 9号 1952頁 1996/09 査読有 研究論文(学術雑誌)
  • IMMUNOHISTOCHEMICAL LOCALIZATION OF ANDROGEN RECEPTOR IN THE HUMAN OVARY THROUGHOUT THE MENSTRUAL-CYCLE IN RELATION TO ESTROGEN AND PROGESTERONE-RECEPTOR EXPRESSION HUMAN REPRODUCTION 7巻 2号 184頁 1992/02 査読有 研究論文(学術雑誌)
  • Are membrane-bound peptidases new regulators of follicular growth? NEW HORIZONS IN REPRODUCTIVE MEDICINE 12巻 301頁 1997 査読有 研究論文(プロシーディング)
  • EXPRESSION OF AMINOPEPTIDASE-N AND NEUTRAL ENDOPEPTIDASE ON THE ENDOMETRIAL STROMAL CELLS IN ENDOMETRIOSIS AND ADENOMYOSIS HUMAN REPRODUCTION 7巻 9号 1326頁 1992/10 査読有 研究論文(学術雑誌)
  • ENDOCRINE AND IMMUNE IMPLICATIONS OF HUMAN ENDOMETRIAL DECIDUALIZATION IN IMPLANTATION FRONTIERS IN HUMAN REPRODUCTION 626巻 321頁 1991 査読有 研究論文(プロシーディング)
  • INTEGRIN ALPHA-6 IS A DIFFERENTIATION ANTIGEN OF HUMAN GRANULOSA-CELLS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 80巻 10号 2899頁 1995/10 査読有 研究論文(学術雑誌)
  • THE EXPRESSION OF PEPTIDASE ANTIGENS, CD10 NEUTRAL ENDOPEPTIDASE, CD13 AMINOPEPTIDASE-N, AND CD26 DIPEPTIDYL PEPTIDASE-IV IN HUMAN ENDOMETRIUM ENDOCRINOLOGY OF EMBRYO-ENDOMETRIUM INTERACTIONS 67頁 1994 査読有 研究論文(プロシーディング)
  • DIPEPTIDYL PEPTIDASE-IV AS A DIFFERENTIATION MARKER OF THE HUMAN ENDOMETRIAL GLANDULAR CELLS HUMAN REPRODUCTION 7巻 9号 1189頁 1992/10 査読有 研究論文(学術雑誌)
  • OVARIAN CYTOKINES IN REGULATION OF GRANULOSA-CELL FUNCTION PROGRESS IN ENDOCRINOLOGY 3巻 577頁 1993 査読有 研究論文(プロシーディング)
  • DIFFERENTIAL EXPRESSION OF AMINOPEPTIDASE-N ON HUMAN OVARIAN GRANULOSA AND THECA CELLS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 74巻 1号 91頁 1992/01 査読有 研究論文(学術雑誌)
  • HUMAN ENDOMETRIAL STROMAL CELLS AND DECIDUAL CELLS EXPRESS CLUSTER OF DIFFERENTIATION (CD)13 ANTIGEN AMINOPEPTIDASE-N AND CD10 ANTIGEN NEUTRAL ENDOPEPTIDASE BIOLOGY OF REPRODUCTION 46巻 3号 328頁 1992/03 査読有 研究論文(学術雑誌)
  • INTERACTIONS BETWEEN INTERFERON-GAMMA, TUMOR-NECROSIS-FACTOR-ALPHA, AND INTERLEUKIN-1 IN MODULATING PROGESTERONE AND ESTRADIOL PRODUCTION BY HUMAN LUTEINIZED GRANULOSA-CELLS IN CULTURE HUMAN REPRODUCTION 7巻 10号 1361頁 1992/11 査読有 研究論文(学術雑誌)
  • EFFECTS OF INTERFERON ON THE STEROIDOGENIC FUNCTIONS AND PROLIFERATION OF IMMATURE PORCINE GRANULOSA-CELLS IN CULTURE BIOLOGY OF REPRODUCTION 47巻 6号 931頁 1992/12 査読有 研究論文(学術雑誌)
  • HUMAN-LEUKOCYTE ANTIGEN-DR IS A DIFFERENTIATION ANTIGEN FOR HUMAN GRANULOSA-CELLS BIOLOGY OF REPRODUCTION 49巻 4号 705頁 1993/10 査読有 研究論文(学術雑誌)
  • A NEW MONOCLONAL-ANTIBODY (POG-1) DETECTS A DIFFERENTIATION ANTIGEN OF PORCINE GRANULOSA AND THECAL CELLS AND INDICATES HETEROGENEITY OF THECAL-STROMAL CELLS ENDOCRINOLOGY 134巻 3号 1132頁 1994/03 査読有 研究論文(学術雑誌)
  • HUMAN LUTEAL CELLS EXPRESS LEUKOCYTE FUNCTIONAL ANTIGEN (LFA)-3 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 80巻 1号 78頁 1995/01 査読有 研究論文(学術雑誌)
  • Granulosa cells express integrin alpha 6: Possible involvement of integrin alpha 6 in folliculogenesis HORMONE RESEARCH 46巻 24頁 1996 査読有 研究論文(学術雑誌)
  • A MOUSE MONOCLONAL-ANTIBODY, S2N8, DETECTS A 140-KDA PROTEIN ON THE SURFACE OF HUMAN ENDOMETRIAL STROMAL CELLS AND DECIDUAL CELLS HUMAN REPRODUCTION 10巻 5号 1311頁 1995/05 査読有 研究論文(学術雑誌)
  • A differentiation antigen of human large luteal cells in corpora lutea of the menstrual cycle and early pregnancy BIOLOGY OF REPRODUCTION 54巻 6号 1173頁 1996/06 査読有 研究論文(学術雑誌)
  • A new assisted hatching technique using a piezo-micromanipulator FERTILITY AND STERILITY 69巻 4号 784頁 1998/04 査読有 研究論文(学術雑誌)
  • Functional roles of cell surface peptidases in reproductive organs Reproductive Medicine and Biology 3巻 4号 165頁 2004 査読有 研究論文(学術雑誌)
  • Trophoblasts acquire a chernokine receptor, CCR1, as they differentiate towards invasive phenotype DEVELOPMENT 130巻 22号 5519頁 2003/11 査読有 研究論文(学術雑誌)
  • Melanoma cell adhesion molecule (MCAM/CD146) is expressed on human luteinizing granulosa cells: enhancement of its expression by hCG, interleukin-1 and tumour necrosis factor-alpha MOLECULAR HUMAN REPRODUCTION 9巻 6号 311頁 2003/06 査読有 研究論文(学術雑誌)
  • Cyclic AMP enhances the expression of an extravillous trophoblast marker, melanoma cell adhesion molecule, in choriocarcinoma cell JEG3 and human chorionic villous explant cultures MOLECULAR HUMAN REPRODUCTION 9巻 6号 359頁 2003/06 査読有 研究論文(学術雑誌)
  • Acute elevation of plasma D-dimer levels associated with rupture of an ovarian endometriotic cyst: Case report HUMAN REPRODUCTION 18巻 2号 338頁 2003/02 査読有 研究論文(学術雑誌)
  • 当科において腹腔鏡下手術が適応となった不妊症症例における術後妊娠率と子宮内膜症の関連についての検討 小阪 謙三,吉岡 信也,江川 美保,西岡 良泰,佐藤 幸保,巽 啓司,樋口 壽宏,藤原 浩,藤井 信吾 産婦人科の進歩 55巻 1号 106頁 2003/02 査読有 
  • Human peripheral blood mononuclear cells enhance cell-cell interaction between human endometrial epithelial cells and BeWo-cell spheroids HUMAN REPRODUCTION 18巻 1号 19頁 2003/01 査読有 研究論文(学術雑誌)
  • Expression of Ly-6A/E in the mouse uterus during implantation period MOLECULAR REPRODUCTION AND DEVELOPMENT 58巻 2号 159頁 2001/02 査読有 研究論文(学術雑誌)
  • Is endothelin converting enzyme-1 the new regulator of corpora lutea? CELL-SURFACE AMINOPEPTIDASES: BASIC AND CLINICAL ASPECTS 1218巻 223頁 2001 査読有 研究論文(プロシーディング)
  • CD9 is expressed on human endometrial epithelial cells in association with integrins alpha(6), alpha(3) and beta(1) MOLECULAR HUMAN REPRODUCTION 6巻 3号 252頁 2000/03 査読有 研究論文(学術雑誌)
  • Co-expression of integrin-associated protein (IAP/CD47) and its ligand thrombospondin-1 on human granulosa and large luteal cells MOLECULAR HUMAN REPRODUCTION 5巻 10号 920頁 1999/10 査読有 研究論文(学術雑誌)
  • CD9 is expressed on the cell surface of human granulosa cells and associated with integrin alpha(6)beta(1) MOLECULAR HUMAN REPRODUCTION 5巻 4号 303頁 1999/04 査読有 研究論文(学術雑誌)
  • CD9 is expressed in extravillous trophoblasts in association with integrin alpha(3) and integrin alpha(5) MOLECULAR HUMAN REPRODUCTION 5巻 2号 162頁 1999/02 査読有 研究論文(学術雑誌)
  • Administration of thymocytes derived from nonpregnant mice induces an endometrial receptive stage and leukaemia inhibitory factor expression in the uterus HUMAN REPRODUCTION 13巻 10号 2888頁 1998/10 査読有 研究論文(学術雑誌)
  • A monoclonal antibody, HCL-2, raised against human luteal cells reacts with apolipoprotein-B and detects the uptake of low density lipoprotein by luteinizing granulosa cells HUMAN REPRODUCTION 13巻 4号 936頁 1998/04 査読有 研究論文(学術雑誌)
  • Stage-specific uptake of apolipoprotein-B in ovarian follicles and corpora lutea of the menstrual cycle and early pregnancy HUMAN REPRODUCTION 13巻 4号 944頁 1998/04 査読有 研究論文(学術雑誌)
  • Ephrin B1 is expressed on human luteinizing granulosa cells in corpora lutea of the early luteal phase: The possible involvement of the B class Eph-ephrin system during corpus luteum formation JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 88巻 9号 4384頁 2003/09 査読有 研究論文(学術雑誌)
  • Involvement of dipeptidyl peptidase IV in extravillous trophoblast invasion and differentiation JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 87巻 9号 4287頁 2002/09 査読有 研究論文(学術雑誌)
  • Membrane-bound carboxypeptidase-M is expressed on human ovarian follicles and corpora lutea of menstrual cycle and early pregnancy MOLECULAR HUMAN REPRODUCTION 4巻 7号 709頁 1998/07 査読有 研究論文(学術雑誌)
  • The influence of food intake on female reproductive function in young women Fujiwara T,Nakata R,Fujiwara H Current Trends Endocrinology 1巻 1号 137頁 2005 査読無
  • Regulation of reproductive function by membrane-bound cell surface peptidases Fujiwara H,Nakata R,Fujiwara T,Ueda M,Maeda M Current topics in Biochemical Research 6巻 6号 1頁 2004 査読無
  • New regulatory mechanisms for human extravillous trophoblast invasion Reproductive Medicine and Biology 4巻 3号 189頁 2005 査読有
  • Multiple luteinizing hormone receptor (LHR) protein variants, interspecies reactivity of anti-LHR mAb clone 3B5, subcellular localization of LHR in human placenta, pelvic floor and brain, and possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders and Alzheimer's disease Reproductive Biology and Endocrinology 1巻 46頁 2004/06/03 査読有
  • Human extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 313巻 4号 962頁 2004/01 査読有 研究論文(学術雑誌)
  • 【生殖とサイトカイン】黄体機能とサイトカイン 藤原浩,吉岡信也,江川 美保,藤井信吾 HORMONE FRONTIER IN GYNECOLOGY 10巻 1号 45頁 2003/03 査読無 
  • Laminin and fibronectin concentrations of the follicular fluid correlate with granulosa cell luteinization and oocyte quality Reproductive Medicine and Biology 3巻 1号 43頁 2004 査読有 研究論文(学術雑誌)
  • Human migrating extravillous trophoblasts express a cell surface peptidase, carboxypeptidase-M MOLECULAR HUMAN REPRODUCTION 9巻 12号 799頁 2003/12 査読有 研究論文(学術雑誌)
  • Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166) JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 88巻 7号 3437頁 2003/07 査読有 研究論文(学術雑誌)
  • Human endometrial epithelial cells express ephrin A1: Possible interaction between human blastocysts and endometrium via Eph-ephrin system JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 87巻 12号 5801頁 2002/12 査読有 研究論文(学術雑誌)
  • 【難治性不妊の非ART治療】黄体機能不全 江川 美保,吉岡信也,江川晴人,小阪謙三,藤原浩,藤井信吾 産婦人科治療 85巻 5号 508頁 2002/11 査読無 
  • Peripheral blood mononuclear cells in early pregnancy promote invasion of human choriocarcinoma cell line, BeWo cells HUMAN REPRODUCTION 17巻 2号 473頁 2002/02 査読有 研究論文(学術雑誌)
  • Human peripheral blood mononuclear cells (PBMC) in early pregnancy promote embryo invasion in vitro: HCG enhances the effects of PBMC HUMAN REPRODUCTION 17巻 1号 207頁 2002/01 査読有 研究論文(学術雑誌)
  • Bestatin, an inhibitor of aminopeptidase N, enhanced follicular growth in mice CELL-SURFACE AMINOPEPTIDASES: BASIC AND CLINICAL ASPECTS 1218巻 211頁 2001 査読有 研究論文(プロシーディング)
  • Epoxide hydrolase affects estrogen production in the human ovary ENDOCRINOLOGY 141巻 9号 3353頁 2000/09 査読有 研究論文(学術雑誌)
  • Human granulosa cells express integrin alpha(2) and collagen type IV: possible involvement of collagen type IV in granulosa cell luteinization MOLECULAR HUMAN REPRODUCTION 5巻 7号 607頁 1999/07 査読有 研究論文(学術雑誌)
  • Peripheral blood mononuclear cells stimulate progesterone production by luteal cells derived from pregnant and non-pregnant women: possible involvement of interleukin-4 and interleukin-10 in corpus luteum function and differentiation HUMAN REPRODUCTION 13巻 10号 2738頁 1998/10 査読有 研究論文(学術雑誌)
  • Bestatin, an aminopeptidase inhibitor, promotes follicular growth and ovulation suppressed by stress in mice ENDOCRINE JOURNAL 45巻 4号 547頁 1998/08 査読有 研究論文(学術雑誌)
  • Ovulation defect and its restoration by bone marrow transplantation in osteopetrotic mutant mice of Mitf(mi)/Mitf(mi) genotype BIOLOGY OF REPRODUCTION 57巻 6号 1394頁 1997/12 査読有 研究論文(学術雑誌)
  • Integrin alpha(5) is expressed on human luteinizing granulosa cells during corpus luteum formation, and its expression is enhanced by human chorionic gonadotrophin in vitro MOLECULAR HUMAN REPRODUCTION 3巻 11号 979頁 1997/11 査読有 研究論文(学術雑誌)
  • Human chorionic gonadotropin (HCG) activates monocytes to produce interleukin-8 via a different pathway from luteinizing hormone/HCG receptor system JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 87巻 11号 5199頁 2002/11 査読有 研究論文(学術雑誌)
  • Immune cells contribute to systemic cross-talk between the embryo and mother during early pregnancy in cooperation with the endocrine system Reproductive Medicine and Biology 5巻 1号 19頁 2006 査読有 研究論文(学術雑誌)
  • APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 457巻 3号 295頁 2015/02 査読有 研究論文(学術雑誌)
  • Concurrent estrogen action was essential for maximal progestin effect in oral contraceptives FERTILITY AND STERILITY 101巻 5号 1337頁 2014/05 査読有 研究論文(学術雑誌)
  • Imatinib sensitizes endometrial cancer cells to cisplatin by targeting CD117-positive growth-competent cells CANCER LETTERS 345巻 1号 106頁 2014/04 査読有 研究論文(学術雑誌)
  • Eph-Ephrin A System Regulates Human Choriocarcinoma-Derived JEG-3 Cell Invasion INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 23巻 3号 576頁 2013/03 査読有 研究論文(学術雑誌)
  • Alterations of circulating endothelial cell and endothelial progenitor cell counts around the ovulation Journal of Clinical Endocrinology and Metabolism 97巻 11号 4182頁 2012/11 査読有 研究論文(学術雑誌)
  • Laeverin/aminopeptidase Q induces trophoblast invasion during human early placentation HUMAN REPRODUCTION 27巻 5号 1267頁 2012/05 査読有 研究論文(学術雑誌)
  • Intrauterine Administration of Peripheral Blood Mononuclear Cells Enhances Early Development of the Pre-Implantation Bovine Embryo MOLECULAR REPRODUCTION AND DEVELOPMENT 77巻 11号 954頁 2010/11 査読有 研究論文(学術雑誌)
  • Is the zona pellucida an intrinsic source of signals activating maternal recognition of the developing mammalian embryo? JOURNAL OF REPRODUCTIVE IMMUNOLOGY 81巻 1号 1頁 2009/07 査読有 研究論文(学術雑誌)
  • Do circulating blood cells contribute to maternal tissue remodeling and embryo-maternal cross-talk around the implantation period? MOLECULAR HUMAN REPRODUCTION 15巻 6号 335頁 2009/06 査読有 研究論文(学術雑誌)
  • Integrin alpha 5 is involved in fibronectin-induced human extravillous trophoblast invasion JOURNAL OF REPRODUCTIVE IMMUNOLOGY 73巻 1号 1頁 2007/02 査読有 研究論文(学術雑誌)
  • Intrauterine administration of autologous peripheral blood mononuclear cells promotes implantation rates in patients with repeated failure of IVF-embryo transfer HUMAN REPRODUCTION 21巻 12号 3290頁 2006/12 査読有 研究論文(学術雑誌)
  • Aminopeptidase Q/Laeverin Handbook of Proteolytic Enzymes 1巻 442頁 2013 査読有 その他
  • Membrane-Bound Peptidases Regulate Human Extravillous Trophoblast Invasion Placenta 28巻 S70頁 2007/04 査読有 研究論文(学術雑誌)
  • EphrinA1 stimulates cell attachment and inhibits cell aggregation through the EphA receptor pathway in human endometrial carcinoma-derived Ishikawa cells HUMAN REPRODUCTION 26巻 5号 1163頁 2011/05 査読有 研究論文(学術雑誌)
  • Vascular endothelial growth factor production by circulating immune cells is elevated in ovarian hyperstimulation syndrome HUMAN REPRODUCTION 22巻 6号 1647頁 2007/06 査読有 研究論文(学術雑誌)
  • Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases JOURNAL OF BIOLOGICAL CHEMISTRY 282巻 28号 20088頁 2007/07 査読有 研究論文(学術雑誌)
  • Eph-ephrin A system regulates murine blastocyst attachment and spreading DEVELOPMENTAL DYNAMICS 235巻 12号 3250頁 2006/12 査読有 研究論文(学術雑誌)
  • Nerve-sparing abdominal radical trachelectomy: a novel concept to preserve uterine branches of pelvic nerves EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY 193巻 5頁 2015/10 査読有 研究論文(学術雑誌)
  • Tamoxifen-induced ovarian hyperstimulation during premenopausal hormonal therapy for breast cancer in Japanese women SPRINGERPLUS 4巻 425頁 2015/08 査読有 研究論文(学術雑誌)
  • Involvement of VCAM1 in the bovine conceptus adhesion to the uterine endometrium REPRODUCTION 148巻 2号 119頁 2014/08 査読有 研究論文(学術雑誌)
  • Extravillous trophoblast cell invasion is promoted by the CD44-hyaluronic acid interaction PLACENTA 35巻 3号 163頁 2014/03 査読無 研究論文(学術雑誌) 
  • Regulation of human extravillous trophoblast function by membrane-bound peptidases. Fujiwara H,Higuchi T,Sato Y,Nishioka Y,Zeng BX,Yoshioka S,Tatsumi K,Ueda M,Maeda M Biochimica et biophysica acta 1751巻 1号 26頁 2005/08 査読有
  • Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries BLOOD 106巻 2号 428頁 2005/07 査読有 研究論文(学術雑誌)
  • Platelets are novel regulators of neovascularization and luteinization during human corpus luteum formation ENDOCRINOLOGY 148巻 7号 3056頁 2007/07 査読有 研究論文(学術雑誌)
  • Monoamine oxidase A is highly expressed by the human corpus luteum of pregnancy REPRODUCTION 136巻 3号 367頁 2008/09 査読有 研究論文(学術雑誌)
  • Histidine 379 of Human Laeverin/Aminopeptidase Q, a Nonconserved Residue within the Exopeptidase Motif, Defines Its Distinctive Enzymatic Properties JOURNAL OF BIOLOGICAL CHEMISTRY 284巻 50号 34692頁 2009/12 査読有 研究論文(学術雑誌)
  • Ephrin A1 induces intercellular dissociation in Ishikawa cells: possible implication of the Eph-ephrin A system in human embryo implantation HUMAN REPRODUCTION 26巻 2号 299頁 2011/02 査読有 研究論文(学術雑誌)
  • Management of fetal death with placenta previa JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE 25巻 2号 196頁 2012/02 査読有 研究論文(学術雑誌)
  • Prenatal treatment of meconium peritonitis with urinary trypsin inhibitor ULTRASOUND IN OBSTETRICS & GYNECOLOGY 37巻 3号 366頁 2011/03 査読有 研究論文(学術雑誌)
  • Prenatal diagnosis of anterior sacral meningocele ULTRASOUND IN OBSTETRICS & GYNECOLOGY 37巻 4号 493頁 2011/04 査読有 研究論文(学術雑誌)
  • Management of retained products of conception with marked vascularity JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 37巻 5号 458頁 2011/05 査読有 研究論文(学術雑誌)
  • Chemical Characterization of N-Linked Oligosaccharide As the Antigen Epitope Recognized by an Anti-Sperm Auto-Monoclonal Antibody, Ts4 PLOS ONE 10巻 7号 e0133784頁 2015/07 査読有 研究論文(学術雑誌)
  • Prenatal Findings in Congenital Leukemia: A Case Report FETAL DIAGNOSIS AND THERAPY 29巻 4号 325頁 2011 査読有 研究論文(学術雑誌)
  • Overexpression of TEX101, a potential novel cancer marker, in head and neck squamous cell carcinoma CANCER BIOMARKERS 12巻 3号 141頁 2012 査読有 研究論文(学術雑誌)
  • Administration of peripheral blood mononuclear cells into the uterine horn to improve pregnancy rate following bovine embryo transfer ANIMAL REPRODUCTION SCIENCE 117巻 1-2号 18頁 2010/01 査読有 研究論文(学術雑誌)
  • Successful recovery from delayed amniotic fluid embolism with prolonged cardiac resuscitation JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 37巻 8号 1122頁 2011/08 査読有 研究論文(学術雑誌)
  • Intrauterine administration of autologous peripheral blood mononuclear cells increases clinical pregnancy rates in frozen/thawed embryo transfer cycles of patients with repeated implantation failure JOURNAL OF REPRODUCTIVE IMMUNOLOGY 92巻 1-2号 82頁 2011/12 査読有 研究論文(学術雑誌)
  • Functions of interferon tau as an immunological regulator for establishment of pregnancy Reproductive Medicine and Biology 11巻 3号 109頁 2012 査読有
  • Middle cerebral artery-peak systolic velocity in dizygotic twins with anti-E alloimmunization JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 36巻 6号 1236頁 2010/12 査読有 研究論文(学術雑誌)
  • Role of platelets in placentation MEDICAL MOLECULAR MORPHOLOGY 43巻 3号 129頁 2010/09 査読有
  • Mechanism of maternal vascular remodeling during human pregnancy Reproductive Medicine and Biology 11巻 1号 27頁 2012 査読有
  • Time Restriction of Food Intake During the Circadian Cycle Is a Possible Regulator of Reproductive Function in Postadolescent Female Rats. Current developments in nutrition 3巻 4号 nzy093頁 2019/04 査読有 研究論文(学術雑誌)
  • Twin anemia-polycythemia sequence with blood chimerism in monochorionic dizygotic opposite-sex twins. The journal of obstetrics and gynaecology research 45巻 6号 1201頁 2019/06 査読有
  • Continuous model of conceptus implantation to the maternal endometrium JOURNAL OF ENDOCRINOLOGY 233巻 1号 R53頁 2017/04 査読有
  • Platelets are a possible regulator of human endometrial re-epithelialization during menstruation AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY 77巻 1号 2017/01 査読有 研究論文(学術雑誌)
  • CD9 suppresses human extravillous trophoblast invasion PLACENTA 47巻 105頁 2016/11 査読有 研究論文(学術雑誌)
  • Dual Positive Regulation of Embryo Implantation by Endocrine and Immune Systems - Step-by-Step Maternal Recognition of the Developing Embryo AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY 75巻 3号 281頁 2016/03 査読有
  • Role of circulating blood cells in maternal tissue remodeling and embryo-maternal cross talk Uterine Endometrial Function 49頁 2016/01/01 査読無 その他 
  • Conceptus implantation and placentation: molecules related to epithelial–mesenchymal transition, lymphocyte homing, endogenous retroviruses, and exosomes Reproductive Medicine and Biology 15巻 1号 1頁 2016/01/01 査読有 研究論文(学術雑誌)
  • Three-dimensional evaluation of murine ovarian follicles using a modified CUBIC tissue clearing method Reproductive Biology and Endocrinology 16巻 1号 72頁 2018/08/02 査読有 研究論文(学術雑誌)
  • A successful case of neoadjuvant chemotherapy and radical hysterectomy during pregnancy for advanced uterine cervical cancer accompanied by neonatal erythroderma. Kayahashi K,Mizumoto Y,Myojo S,Mitani Y,Tajima A,Fujiwara H The journal of obstetrics and gynaecology research 2018/07 査読有
  • Immediate elimination of injured white matter tissue achieves a rapid axonal growth across the severed spinal cord in adult rats Neuroscience Research 131巻 19頁 2018/06/01 査読有 研究論文(学術雑誌)
  • Successful detection of SRY gene via fine needle biopsy: A case of extragenital gestational choriocarcinoma in the kidney. Molecular and clinical oncology 7巻 6号 1057頁 2017/12 査読有 研究論文(学術雑誌)
  • Prenatal diagnosis facilitated prompt enzyme replacement therapy for prenatal benign hypophosphatasia. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 40巻 1号 132頁 2020/01 査読有 研究論文(学術雑誌)
  • Factors Regulating Human Extravillous Trophoblast Invasion: Chemokine-peptidase and CD9-integrin Systems. Current pharmaceutical biotechnology 19巻 10号 764頁 2018 査読有 研究論文(学術雑誌)
  • Embryo transfer associated with hormone replacement therapy cycles using assisted reproductive technology increases placenta accreta spectrum. The journal of obstetrics and gynaecology research 45巻 12号 2394頁 2019/12 査読有 研究論文(学術雑誌)
  • TEX101, a glycoprotein essential for sperm fertility, is required for stable expression of Ly6k on testicular germ cells SCIENTIFIC REPORTS 6巻 23616頁 2016/03 査読有 研究論文(学術雑誌)
  • Subserous invasion of VEGF-C-producing cancer cells is a possible risk factor for ileal ulceration in the non-metastatic mucosal layer during bevacizumab-combined chemotherapy for recurrent ovarian cancer: A case report. Molecular and clinical oncology 7巻 5号 820頁 2017/11 査読有 研究論文(学術雑誌)
  • Identification of an anti-sperm auto-monoclonal antibody (Ts4)-recognized molecule in the mouse sperm acrosomal region and its inhibitory effect on fertilization in vitro JOURNAL OF REPRODUCTIVE IMMUNOLOGY 115巻 6頁 2016/06 査読有 研究論文(学術雑誌)
  • Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma. Obata T,Nakamura M,Mizumoto Y,Iizuka T,Ono M,Terakawa J,Daikoku T,Fujiwara H PloS one 12巻 11号 e0188641頁 2017/11 査読有 研究論文(学術雑誌)
  • APOBEC3G is increasingly expressed on the human uterine cervical intraepithelial neoplasia along with disease progression AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY 78巻 4号 2017/10 査読有 研究論文(学術雑誌)
  • Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation Scientific Reports 8巻 1号 9745頁 2018/12/01 査読有 研究論文(学術雑誌)
  • Platelet-derived microparticles and soluble factors differentially regulate human endometrial epithelial cell movement AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY 77巻 4号 2017/04 査読有 研究論文(学術雑誌)
  • Synchronous endometrioid adenocarcinomas in the uterine cervix and corpus JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 42巻 10号 1390頁 2016/10 査読有 研究論文(学術雑誌)
  • NUP62: the target of an anti-sperm auto-monoclonal antibody during testicular development. Reproduction (Cambridge, England) 158巻 6号 503頁 2019/12 査読有 研究論文(学術雑誌)
  • Comparison Study of BD Onclarity HPV With digene HC2 High-Risk HPV DNA Test and Roche Cobas 4800 HPV for Detecting High-Risk Human Papillomavirus in Japan. Nakamura M,Nakade K,Orisaka S,Iwadare J,Mizumoto Y,Fujiwara H American journal of clinical pathology 151巻 3号 263頁 2018/09 査読有 研究論文(学術雑誌)
  • Giant fetal hydrometrocolpos associated with cloacal anomaly causing postnatal respiratory distress JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 43巻 11号 1769頁 2017/11 査読有 研究論文(学術雑誌)
  • Visualization of the Retina in Intact Eyes of Mice and Ferrets Using a Tissue Clearing Method. Translational vision science & technology 9巻 3号 1頁 2020/02/07 研究論文(学術雑誌)
  • Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells. Cancer science 109巻 1号 231頁 2018/01 査読有 研究論文(学術雑誌)
  • Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing VIROLOGY 485巻 460頁 2015/11 査読有 研究論文(学術雑誌)
  • FDG-PET-positive ovarian thecoma with GLUT5 expression: Five cases JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 43巻 3号 599頁 2017/03 査読有 研究論文(学術雑誌)
  • Acquired hemophilia A manifesting as plasma transfusion-uncontrolled severe bleeding 2 weeks after chorioamnionitis-induced abortion JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 43巻 4号 763頁 2017/04 査読有 研究論文(学術雑誌)
  • Ovarian hyperstimulation closely associated with resumption of follicular growth after chemotherapy during tamoxifen treatment in premenopausal women with breast cancer: a multicenter retrospective cohort study. BMC cancer 20巻 1号 67頁 2020/01/29 査読有 研究論文(学術雑誌)
  • Amniotic epithelial cells damage by oxidative stress in cases of diffuse chorioamniotic hemosiderosis. The journal of obstetrics and gynaecology research 45巻 10号 2095頁 2019/10 査読有 研究論文(学術雑誌)
  • Prenatal diagnosis facilitated prompt enzyme replacement therapy for prenatal benign hypophosphatasia. Ishijima Yuka,Iizuka Takashi,Kagami Kyosuke,Masumoto Sakiko,Nakade Kyohei,Mitani Yusuke,Niida Yo,Watanabe Atsushi,Yamazaki Rena,Ono Masanori,Fujiwara Hiroshi Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 1606177巻 1606177頁 2019 査読有 
  • Quantitative measurement of a candidate serum biomarker peptide derived from α2-HS-glycoprotein, and a preliminary trial of multidimensional peptide analysis in females with pregnancy-induced hypertension. Hamamura K,Yanagida M,Ishikawa H,Banzai M,Yoshitake H,Nonaka D,Tanaka K,Sakuraba M,Miyakuni Y,Takamori K,Nojima M,Yoshida K,Fujiwara H,Takeda S,Araki Y Annals of clinical biochemistry 55巻 2号 287頁 2018/03/01 査読有 研究論文(学術雑誌)
  • Three-dimensional visualization of intrauterine conceptus through the uterine wall by tissue clearing method SCIENTIFIC REPORTS 7巻 1号 5964頁 2017/07 査読有 研究論文(学術雑誌)
  • Familial discrepancy of clinical outcomes associated with fibrinogen Dorfen: A case of huge genital hematoma after episiotomy JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 42巻 6号 722頁 2016/06 査読有 研究論文(学術雑誌)
  • The Association and Significance of p53 in Gynecologic Cancers: The Potential of Targeted Therapy. International journal of molecular sciences 20巻 21号 2019/11/04 査読有 研究論文(学術雑誌)
  • Annual report of Reproductive Endocrinology Committee, Japan Society of Obstetrics and Gynecology, 2019. The journal of obstetrics and gynaecology research 45巻 10号 1975頁 2019/10 査読有 研究論文(学術雑誌)
  • IFPA meeting 2018 workshop report II: Abnormally invasive placenta; inflammation and infection; preeclampsia; gestational trophoblastic disease and drug delivery. Albrecht C,Chamley L,Charnock-Jones DS,Collins S,Fujiwara H,Golos T,Grayo S,Hannan N,Harris L,Ichizuka K,Illsley NP,Iwashita M,Kallol S,Al-Khan A,Lash G,Nagamatsu T,Nakashima A,Niimi K,Nomoto M,Redman C,Saito S,Tanimura K,Tomi M,Usui H,Vatish M,Wolfe B,Yamamoto E,O'Tierney-Ginn P Placenta 84巻 9頁 2019/09/01 査読有
  • Novel strategy of ovarian cancer implantation: Pre-invasive growth of fibrin-anchored cells with neovascularization. Cancer science 110巻 8号 2658頁 2019/08 査読有 研究論文(学術雑誌)
  • Post-delivery evaluation of morphological change in vein of galen aneurysmal malformation - possible parameter of long-term prognosis Iizuka Takashi,Arai Takanari,Myojo Subaru,Uchiyama Naoyuki,Yoshida Kotaro,Fujiwara Hiroshi CASE REPORTS IN PERINATAL MEDICINE 5巻 1号 41頁 2016/03 査読有
  • CD73 as a candidate glycoprotein for a target of a mouse anti-sperm auto-monoclonal antibody, Ts4, which recognizes a bisecting GlcNAc structure in the testicular germ cells Oda Risako,Yoshitake Hiroshi,Kazuno Saiko,Miura Yoshiki,Ueno Takashi,Sakuraba Mayumi,Takamori Kenji,Hasegawa Akiko,Fujiwara Hiroshi,Takeda Satoru,Araki Yoshihiko JOURNAL OF REPRODUCTIVE IMMUNOLOGY 130巻 39頁 2018/11 査読有
  • Hypertensive disorders of pregnancy are associated with dysmenorrhea in early adulthood: A cohort study. The journal of obstetrics and gynaecology research 46巻 11号 2292頁 2020/08/18 査読有 研究論文(学術雑誌)
  • Adolescent Dietary Habit-induced Obstetric and Gynecologic Disease (ADHOGD) as a New Hypothesis-Possible Involvement of Clock System. Nutrients 12巻 5号 2020/05/02 査読有 研究論文(学術雑誌)
  • Emerging Role of Extracellular Vesicles in Embryo-Maternal Communication throughout Implantation Processes. International journal of molecular sciences 21巻 15号 2020/08/01 研究論文(学術雑誌)
  • Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system. Scientific reports 11巻 1号 3833頁 2021/02/15 研究論文(学術雑誌)
  • Brown adipocyte-specific knockout of Bmal1 causes mild but significant impairment of thermogenesis in mice. Molecular metabolism 101202頁 2021/03/03 研究論文(学術雑誌)
  • A case of synchronous high-grade cervical intraepithelial neoplasia and metastatic squamous cell carcinomas of unknown primary in rectum. The journal of obstetrics and gynaecology research 2021/04/18
  • Breakfast Skipping in Female College Students Is a Potential and Preventable Predictor of Gynecologic Disorders at Health Service Centers. Diagnostics (Basel, Switzerland) 10巻 7号 2020/07/13 査読有 研究論文(学術雑誌)
  • A novel third mesh-like myometrial layer connects the longitudinal and circular muscle fibers -A potential stratum to coordinate uterine contractions. Scientific reports 10巻 1号 8274頁 2020/05/19 査読有 研究論文(学術雑誌)
  • Promoting Roles of Embryonic Signals in Embryo Implantation and Placentation in Cooperation with Endocrine and Immune Systems. International journal of molecular sciences 21巻 5号 2020/03/10 査読有 研究論文(学術雑誌)
  • An overview of sex and reproductive immunity from an evolutionary/anthropological perspective. Immunological medicine 1頁 2020/10/11 研究論文(学術雑誌)
  • A direct endoscopic approach for left-sided infrarenal para-aortic lymphadenectomy immediately after hysterectomy for endometrial cancer treatment: left dome formation (LDF). Surgical endoscopy 34巻 8号 3338頁 2020/08 査読有 研究論文(学術雑誌)
  • Wavy Floating Greater Omentum Findings Are Useful for Differentiating the Etiology of Fetal Ascites. Diagnostics (Basel, Switzerland) 11巻 2号 2021/02/17 研究論文(学術雑誌)
  • Mucinous, endometrioid, and serous ovarian cancers with peritoneal dissemination are potent candidates for P-cadherin targeted therapy: a retrospective cohort study. BMC cancer 21巻 1号 32頁 2021/01/07 研究論文(学術雑誌)
  • CD9 suppresses human extravillous trophoblast invasion.  Placenta 2016/11/01 査読有 原著論文 研究論文(学術雑誌)
  • Extravillous trophoblast cell invasion is promoted by the CD44-hyaluronic acid interaction.  Placenta 2014/05/01 査読有 原著論文 研究論文(学術雑誌)
  • APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity.  Biochem Biophys Res Commun 2015/02/01 査読有 原著論文 研究論文(学術雑誌)
  • Nerve-sparing abdominal radical trachelectomy: a novel concept to preserve uterine branches of pelvic nerves.  Eur J Obstet Gynecol Reprod Biol 2015/10/01 査読有 原著論文 研究論文(学術雑誌)
  • Chemical Characterization of N-Linked Oligosaccharide As the Antigen Epitope Recognized by an Anti-Sperm Auto-Monoclonal Antibody, Ts4.  PLoS One 2015/07/01 査読有 原著論文 研究論文(学術雑誌)
  • Tamoxifen-induced ovarian hyperstimulation during premenopausal hormonal therapy for breast cancer in Japanese women.  Springerplus. 19巻 425頁 2015/08/01 査読有 原著論文 研究論文(学術雑誌)
  • Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing Virology 485巻 460-6頁 2015/11/01 査読有
  • Dual Positive Regulation of Embryo Implantation by Endocrine and Immune Systems--Step-by-Step Maternal Recognition of the Developing Embryo.  Am J Reprod Immunol 2016/05/01 査読有 原著論文 研究論文(学術雑誌)
  • TEX101, a glycoprotein essential for sperm fertility, is required for stable expression of Ly6k on testicular germ cells.  Sci Rep 23巻 23616頁 2016/05/01 査読有 原著論文 研究論文(学術雑誌)
  • Familial discrepancy of clinical outcomes associated with fibrinogen Dorfen: A case of huge genital hematoma after episiotomy.  J Obstet Gynaecol Res 42巻 722-725頁 2016/06/01 査読有 原著論文 研究論文(学術雑誌)
  • Identification of an anti-sperm auto-monoclonal antibody (Ts4)-recognized molecule in the mouse sperm acrosomal region and its inhibitory effect on fertilization in vitro.  J Reprod Immunol 115巻 6-13頁 2016/06/01 査読有 原著論文 研究論文(学術雑誌)
  • Synchronous endometrioid adenocarcinomas in the uterine cervix and corpus.  J Obstet Gynaecol Res. 42巻 1390-1394頁 2016/10/01 査読有 原著論文 研究論文(学術雑誌)
  • Platelets are a possible regulator of human endometrial re-epithelialization during menstruation.  Am J Reprod Immunol.  77巻 2017/01/01 査読有 研究論文(学術雑誌)
  • FDG-PET-positive ovarian thecoma with GLUT5 expression: Five cases.  J Obstet Gynaecol Res. 43巻 599-603頁 2017/03/01 査読有
  • Acquired hemophilia A manifesting as plasma transfusion-uncontrolled severe bleeding 2 weeks after chorioamnionitis-induced abortion.  J Obstet Gynaecol Res.  2017/02/02
  • Platelet-derived microparticles and soluble factors differentially regulate human endometrial epithelial cell movement.  Am J Reprod Immunol. 2017/02/07 査読有
  • Continuous model of conceptus implantation to the maternal endometrium.  J Endocrinol.  233巻 R53-R65頁 2017/02/01 査読有
  • Imatinib sensitizes endometrial cancer cells to cisplatin by targeting CD117-positive growth-competent cells Cancer Letters 345巻 1号 106-114頁 2014/04/01 
  • Involvement of VCAM1 in the bovine conceptus adhesion to the uterine endometrium Reproduction 148巻 2号 119-127頁 2014/08/01 
  • Concurrent estrogen action was essential for maximal progestin effect in oral contraceptives Fertility and Sterility 101巻 5号 1337-1343頁 2014/01/01 

講演・口頭発表等

その他(報告書など)

芸術・フィールドワーク

特許

共同研究希望テーマ

科研費

競争的資金・寄付金等

共同研究・受託研究実績

A-STEP採択課題

学域・学類担当授業科目

○産科婦人科学臨床実習BSL(2017)
○生殖・胎生・周産期(2017)
○生殖・胎生・周産期(2016)
○小児母性疾病論(2016)
○産科婦人科学臨床実習BSL(2016)
○小児母性疾病論(2015)
○生殖・胎生・周産期(2015)
○産科婦人科学臨床実習BSL(2015)
○生殖・胎生・周産期(2014)

大学院担当授業科目

○女性生殖臓器病態学特論(2017)
○女性生殖臓器病態学特論(2017)
○女性生殖臓器病態学特論(2016)
○女性生殖臓器病態学特論(2016)
○分子移植学特論(2015)
○分子移植学特論(2014)

他大学の客員教授

教育活動(FD)に関する研究

国際事業協力

留学生参加の社会活動

審議会等の参加

講演可能なテーマ

その他公的社会活動

このページの先頭へ