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Researcher Information

last modified:2020/06/04

Professor NAKAMURA Hiroyuki

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Faculty, Affiliation

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Division of Environmental Science, Graduate School of Medical Scienc
Division of Advanced Preventive Medical Sciences,Graduate School of Advanced Preventive Medical Sciences
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Environmental and Preventive Medicine TEL:076-265-2218 FAX:076-234-4233

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Graduate School, Division of Medicine Completed
【Academic background(Bachelor's Degree)】
Kanazawa University
【Degree】
Medical Doctor

Career

Year & Month of Birth

Academic Society


The Japanese Society for Hygiene
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Japan Society For Occupational Health
Japan Society For Occupational Health
The Japanese Society Of Health And Human Ecology
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International Commission of Occupational Health
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Japan Epidemiological Association
Japanese Society Of Preventive Medicine
Japan Society Of Adolescentology
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Award

○-(1990)
○-(1991)
○-(2004)
○-(2004)
○-(2004)

Specialities

Hygiene and public health

Speciality Keywords

Public health, Preventive medicine, Industrial medicine, epidemiology, molecular epidemiology, Environmental health, Allergy, stress, Electromagnetics, QOL

Research Themes

Effects of Physical Environmental Factors

We have examined the biological effects of physical environmental factors, such as vibration, noise, low-frequency sound, heat, and electromagnetic waves. We clarified the central and peripheral mechanisms underlying gastric ulcers and miscarriages induced by vibration and the physiological pathogenetic mechanism of vibration-induced white finger disease. In addition, as regards the social problem of the biological impact of microwaves in the current environment of satellite communications, we identified the role of brain opioids during exposure to microwaves in relation to cellular immune function. We also discovered that placenta CRH is related to the adjustment of placenta circulatory function. We propose that although the current exposure standards are within a safe range, there should be continued systematic investigation on the impact of microwaves on a fetus.

Environmental Factors and Molecular Epidemiology on Allergic Diseases

We clarified the effects of environmental factors, especially chemical substances in the environment, on allergic diseases. Simultaneously, we also conducted applied research, such as development of a filter to prevent diesel particles from inducing allergic diseases. We have implemented molecular epidemiological research concerning the environment and genetics of cedar pollen allergy and asthma and identified the susceptibility gene that leads to development in interaction with the environment. We aim to use this research to devise individualized methods of prevention.

Epidemiology on diseases induced by factors of life-styles including nutrition and stress since infancy

Primary prevention of lifestyle diseases and diseases related to nutritional excesses or deficiencies requires attention to propser nutritional intake and lifestyle habits from childhood. Additionally, allergic diseases, which have been on the rise in the recent years, are a major childhook health problem, and have been found to be closely related to stress and psychological problems. This study is intended to describe the effects of various factors related to health issues, such as nutritional intake and conditions, lifestyle habits, and environmental factors, on children’s health, and to develop health education methods for the prevention of disease onset.

Books

  •  The ABC of psychiatric emergencies: aggression, body, and calmatives Elsevier Science 1999

Papers

  •  Chromium, Cadmium, Lead, and Arsenic Concentrations in Water, Vegetables, and Seafood Consumed in a Coastal Area in Northern Vietnam Nguyen Thi Minh Ngoc, Nguyen Van Chuyen, Nguyen Thi Thu Thao, Nguyen Quang Duc, Nguyen Thi Thu Trang, Nguyen Thi Thanh Binh, Hoang Cao Sa, Nguyen Bao Tran, Nguyen Van Ba, Nguyen Van Khai, Ho Anh Son, Pham Van Han, Elizabeth V Wattenberg, Hiroyuki Nakamura, Pham Van Thuc Environ Health Insights 14 1-9 2020/05
  •  Study Protocol for Pleiotropic Effects and Safety of Sodium-Glucose Cotransporter 2 Inhibitor Versus Sulfonylurea in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease Yumie Takeshita, Takehiro Kanamori, Takeo Tanaka, Yuka Kaikoi, Yuki Kita, Noboru Takata, Noriho Iida, Kuniaki Arai, Tatsuya Yamashita, Kenichi Harada, Toshifumi Gabata, Hiroyuki Nakamura, Shuichi Kaneko, Toshinari Takamura Diabetes Ther 11 2 549-560 2020/02
  •  Relationship Between Anti-Erythropoietin Receptor Autoantibodies and Responsiveness to Erythropoiesis-Stimulating Agents in Patients on Hemodialysis: A Multi-Center Cross-Sectional Study Akinori Hara, Yoshitaka Koshino, Yukie Kurokawa, Yasuyuki Shinozaki, Taito Miyake, Shinji Kitajima, Tadashi Toyama, Yasunori Iwata, Norihiko Sakai, Miho Shimizu, Kengo Furuichi, Hiroyuki Nakamura, Takashi Wada Clin Exp Nephrol  24 1 88-95 2020/01
  •  Real-World Effectiveness of Ramelteon and Suvorexant for Delirium Prevention in 948 Patients With Delirium Risk Factors Kotaro Hatta, Yasuhiro Kishi, Ken Wada, Takashi Takeuchi, Naoko Hashimoto, Kiyoko Suda, Toshihiro Taira, Kazuo Tsuchida, Takashi Ohmori, Nobuya Akizuki, Yuko Nishio, Yukiko Nakanishi, Chie Usui, Akiko Kurata, Naoki Horikawa, Hiroshi Eguchi, Shigeo Ito, Hitoshi Muto, Hiroyuki Nakamura, Naohisa Uchimura J Clin Psychiatry 81 1 19m12865 2019/12
  •  Presence of a Synergistic Interaction Between Current Cigarette Smoking and Diabetes Mellitus on Development of Dementia in Older Adults Moeko Noguchi-Shinohara, Kohei Hirako, Makoto Fujiu, Masahiko Sagae, Hikaru Samuta, Hiroyuki Nakamura, Masahito Yamada J Alzheimers Dis 71 3 833-840 2019/10

show all

  •  Neoadjuvant Chemotherapy With Gemcitabine-Based Regimens Improves the Prognosis of Node Positive Resectable Pancreatic Head Cancer Hidehiro Tajima, Tetsuo Ohta, Mitsuyoshi Okazaki, Takahisa Yamaguchi, Yoshinao Ohbatake, Koichi Okamoto, Shinichi Nakanuma, Jun Kinoshita, Isamu Makino, Keishi Nakamura, Tomoharu Miyashita, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Hiroyuki Nakamura Mol Clin Oncol 11 2 157-166 2019/08
  •  Triclosan-induced Alteration of Gut Microbiome and Aggravation of Asthmatic Airway Response in Aeroallergen-sensitized mice. Allergy Hirota R, Ohya Y, Yamamoto-Hanada K, FukutomiI Y, Muto G, Ngatu-Nlandu R, Nakamura T, Nakamura H Allergy 74 5 996-999 2019/05
  •  Relationship between Saturated Fatty Acid Intake and Hypertension and Oxidative Stress Haruki Nakamura, Hiromasa Tsujiguchi, Yasuhiro Kambayashi, Akinori Hara, Sakae Miyagi, Yohei Yamada, Thao Thi Thu Nguyen, Yukari Shimizu, Daisuke Hori, Hiroyuki Nakamura Nutrition 61 8-15 2019/05
  •  Heat Attenuates Sensitivity of Mammalian Cells to Capsaicin Naotoshi Sugimoto, Kentaro Matsuzaki, Masanori Katakura, Hiroyuki Nakamura, Yoshibumi Ueda, Akihiro Yachie, Osamu Shido J Biochem Mol Toxicol 33 5 e22288 2019/05
  •  Relationship between the Intake of n-3 Polyunsaturated Fatty Acids and Depressive Symptoms in Elderly Japanese People: Differences According to Sex and Weight Status Tsujiguchi H, Thi Thu Nguyen T, Goto D, Miyagi S, Kambayashi Y, Hara A, Yamada Y, Nakamura H, Shimizu Y, Hori D, Suzuki F, Hayashi K, Tamai S, Nakamura H Nutrients 11 4 E775 2019/04
  •  Dietary Calcium Intake and Hypertension: Importance of Serum Concentrations of 25-Hydroxyvitamin D Nakamura H, Tsujiguchi H, Hara A, Kambayashi Y, Miyagi S, Thu Nguyen TT, Suzuki K, Tao Y, Sakamoto Y, Shimizu Y, Yamamoto N, Nakamura H Nutrients 11 4 E911 2019/04
  •  Association between Lower Intake of Minerals and Depressive Symptoms among Elderly Japanese Women but Not Men: Findings from Shika Study Thi Thu Nguyen T, Miyagi S, Tsujiguchi H, Kambayashi Y, Hara A, Nakamura H, Suzuki K, Yamada Y, Shimizu Y, Nakamura H Nutrients 11 2 E389 2019/02
  •  Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa T, Nakamura H, Mikami M, Morioka I, Ohya Y Asia Pac Allergy 9 1 e5 2019/01
  •  Corticosterone Inhibits the Expression of Cannabinoid receptor-1 and Cannabinoid Receptor Agonist-Induced Decrease in Cell Viability in Glioblastoma Cells Naotoshi Sugimoto, Hiroaki Ishibashi, Yoshibumi Ueda, Hiroyuki Nakamura, Akihiro Yachie, Takako Ohno-Shosaku Oncol Lett 18 2 1557-1563 2019
  •  Real-world Effectiveness of Antipsychotic Monotherapy and Polytherapy in 1543 Patients With Acute-Phase Schizophrenia Kotaro Hatta, Hana Hasegawa, Atsushi Imai, Yasuhiko Sudo, Fumiyoshi Morikawa, Shigemasa Katayama, Haruo Watanabe, Takuya Ishizuka, Mitsuru Nakamura, Fuminari Misawa, Kiyoshi Fujita, Shigeru Ozaki, Kentaro Umeda, Hiroyuki Nakamura, Yutaka Sawa, Naoya Sugiyama, JAST study group Asian J Psychiatr 40 82-87 2019
  •  Elevated Levels of Serum IL-17A in Community-Dwelling Women with Higher Depressive Symptoms Tsuboi H, Sakakibara H, Minamida Y, Tsujiguchi H, Matsunaga M, Hara A, Nakamura H Behav Sci (Basel) 8 11 E102 2018/11
  •  123I-MIBG myocardial scintigraphy for the diagnosis of DLB: a multicentre 3-year follow-up study Komatsu J, Samuraki M, Nakajima K, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamashina S, Yamasaki J, Yoshita M, Yamada M  J Neurol Neurosurg Psychiatry 89 11 1167-1173 2018/11
  •  Relationship between Dietary n-6 Fatty Acid Intake and Hypertension: Effect of Glycated Hemoglobin Levels Nakamura H, Hara A, Tsujiguchi H, Thi Thu Nguyen T, Kambayashi Y, Miyagi S, Yamada Y, Suzuki K, Shimizu Y, Nakamura H Nutrients 10 12 E1825 2018/11
  •  A prospective naturalistic multicenter study on choice of parenteral medication in psychiatric emergency settings in Japan Hatta K, Katayama S, Morikawa F, Imai A, Fujita K, Fujita A, Ishizuka T, Abe T, Sudo Y, Hashimoto K, Usui C, Nakamura H, Yamanouchi Y, Hirata T; JAST study group Neuropsychopharmacol Rep 38 3 117-123 2018/09
  •  Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes Oshima M, Toyama T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Hara A, Makino H, Wada T PLoS One 13 8 e0201535 2018/08
  •  Relationship between screen time and nutrient intake in Japanese children and adolescents: a cross-sectional observational study Tsujiguchi H, Hori D, Kambayashi Y, Hamagishi T, Asakura H, Mitoma J, Kitaoka M, Anyenda EO, Nguyen TTT, Yamada Y, Hayashi K, Konoshita T, Sagara T, Shibata A, Sasaki S, Nakamura H Environ Health Prev Med 23 1 34- 2018/08
  •  The four-domain structure model of a depression scale for medical students: A cross-sectional study in Haiphong, Vietnam Nguyen TTT, Nguyen NTM, Pham MV, Pham HV, Nakamura H PLoS One 13 3 e0194550 2018/05
  •  Time-series analysis: variation of anti-acetylcholine receptor antibody titer in myasthenia gravis is related to incidence of Mycoplasma pneumoniae and influenza virus infections Iwasa K, Yoshikawa H, Hamaguchi T, Sakai K, Shinohara-Noguchi M, Samuraki M, Takahashi K, Yanase D, Ono K, Ishida C, Yoshita M, Nakamura H Yamada M Neurol Res 40 2 102-109 2018/02
  •  Prevalence of primary aldosteronism without hypertension in the general population: Results in Shika study Karashima S, Kometani M, Tsujiguchi H, Asakura H, Nakano S, Usukura M, Mori S, Ohe M, Sawamura T, Okuda R, Hara A, Takamura T, Yamagishi M, Nakamura H, Takeda Y, Yoneda T Clin Exp Hypertens 40 2 118-125 2018
  •  Higher Blood Vitamin C Levels are Associated with Reduction of Apolipoprotein E E4-related Risks of Cognitive Decline in Women: The Nakajima Study Noguchi-Shinohara M, Abe C, Yuki-Nozaki S, Dohmoto C, Mori A, Hayashi K, Shibata S, Ikeda Y, Sakai K, Iwasa K, Yokogawa M, Ishimiya M, Nakamura H, Yokoji H, Komai K, Nakamura H, Yamada M J Alzheimers Dis 63 4 1289-1297 2018
  •  Relationship between the Use of Parabens and Allergic Diseases in Japanese Adults—A Cross-Sectional Study Yukari Shimizu, Yasuhiro Kambayashi, Hiromasa Tsujiguchi, Akinori Hara, Daisuke Hori, Thao Thi Thu Nguyen, Fumihiko Suzuki, Toshio Hamagishi, Yohei Yamada, Haruki Nakamura, Takahiro Yoshikawa, Koichiro Hayashi, Yuri Hibino, Aki Shibata, Yuma Fukutomi, Yukihiro Ohya, Kiwako Yamamoto-Hanada, Go Muto, Ryoji Hirota, Tadashi Konoshita and Hiroyuki Nakamura Multidisciplinary Scientific Journal 1 1 148-158 2018
  •  Differences in Dementia Beliefs between Non-Demented Public Screeners and In-Home Screeners and Their Potential Impact on Future Dementia Screening Intention: The Nakajima Study Yuki-Nozaki S, Noguchi-Shinohara M, Domoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M J Alzheimers Dis 62 4 1651-1661 2018
  •  Relationship between Vitamin Intake and Depressive Symptoms in Elderly Japanese Individuals: Differences with Gender and Body Mass Index Nguyen TTT, Tsujiguchi H, Kambayashi Y, Hara A, Miyagi S, Yamada Y, Nakamura H, Shimizu Y, Hori D, Suzuki F, Hayashi K, Nakamura H Nutrients 9 12 E1319 2017/12
  •  Relationship between Vitamin Intake and Depressive Symptoms in Elderly Japanese Individuals: Differences with Gender and Body Mass Index Nguyen TTT, Tsujiguchi H, Kambayashi Y, Hara A, Miyagi S, Yamada Y, Nakamura H, Shimizu Y, Hori D, Suzuki F, Hayashi K, Nakamura H Nutrients 9 12 E1319 2017/12
  •  Relationship between Vitamin Intake and Depressive Symptoms in Elderly Japanese Individuals: Differences with Gender and Body Mass Index Nguyen TTT, Tsujiguchi H, Kambayashi Y, Hara A, Miyagi S, Yamada Y, Nakamura H, Shimizu Y, Hori D, Suzuki F, Hayashi K, Nakamura H Nutrients 9 12 E1319 2017/12
  •  Sex- and Age-Specific Associations of Social Status and Health-Related Behaviors with Health Check Attendance: Findings from the Cross-Sectional Kanazawa Study Hiromasa Tsujiguchi, Daisuke Hori, Yasuhiro Kambayashi, Toshio Hamagishi, Hiroki Asakura, Junko Mitoma, Masami Kitaoka, Anyenda Enoch Olando, Nguyen Thi Thu Thao, Yohei Yamada, Koichiro Hayashi, Tadashi Konoshita, Takiko Sagara, Aki Shibata, Hiroyuki Nakamura Health 9 9 1285-1300 2017/09
  •  Clinical and Pathological Significance of Autoantibodies to Erythropoietin Receptor in Type 2 Diabetic Patients With CKD Hara A, Furuichi K, Koshino A, Yasuda H, Tran TTT, Iwata Y, Sakai N, Shimizu M, Kaneko S, Nakamura H, Wada T Kidney Int Rep 3 1 133-141 2017/09
  •  Preventive Effects of Suvorexant on Delirium: A Randomized Placebo-Controlled Trial Hatta K, Kishi Y, Wada K, Takeuchi T, Ito S, Kurata A, Murakami K, Sugita M, Usui C, Nakamura H; DELIRIA-J Group J Clin Psychiatry 78 8 e970-e979 2017/09
  •  The Association of Autism Spectrum Disorders and Symptoms of Asthma, Allergic Rhinoconjunctivitis and Eczema among Japanese Children Aged 3 - 6 Years Daisuke Hori, Hiromasa Tsujiguchi, Yasuhiro Kambayashi, Toshio Hamagishi, Masami Kitaoka, Junko Mitoma, Hiroki Asakura, Fumihiko Suzuki, Enoch Olando Anyenda, Nguyen Thi Thu Thao, Yohei Yamada, Satoko Tamai, Koichiro Hayashi, Yuri Hibino, Aki Shibata, Takiko Sagara, Shinichiro Sasahara, Ichiyo Matsuzaki, Hiroyuki Nakamura Health 9 8 1235-1250 2017/08
  •  Phase I study of weekly palliative chemotherapy with low-dose third-line paclitaxel for biliary tract cancer Tajima H, Ohta T, Shinbashi H, Hirose A, Okazaki M, Yamaguchi T, Ohbatake Y, Okamoto K, Nakanuma S, Sakai S, Kinoshita J, Makino I, Nakamura K, Hayashi H, Oyama K, Inokuchi M, Miyashita T, Takamura H, Ninomiya I, Fushida S, Nakamura H Mol Clin Oncol 6 5 753-757 2017/05
  •  The associations between lifestyles and mental health using the General Health Questionnaire 12-items are different dependently on age and sex: a population-based cross-sectional study in Kanazawa, Japan. Hori D, Tsujiguchi H, Kambayashi Y, Hamagishi T, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Anyenda EO, Nguyen TT, Hibino Y, Shibata A, Hayashi K, Sagara T, Sasahara S, Matsuzaki I, Hatta K, Konoshita T, Nakamura H Environ Health Prev Med 21 6 410-421 2016/11
  •  Exposure to daily ambient particulate polycyclic aromatic hydrocarbons and cough occurrence in adult chronic cough patients: A longitudinal study. Enoch Olando Anyenda, Tomomi Higashi, Yasuhiro Kambayashi, Nguyen Thi Thu Thao, Yoshimasa Michigami, Masaki Fujimura, Johsuke Hara, Hiromasa Tsujiguchi, Masami Kitaoka, Hiroki Asakura, Daisuke Hori, Yohei Yamada, Koichiro Hayashi, Kazuichi Hayakawa, Hiroyuki Nakamura Atmospheric Environment 140 34–41 2016/09
  •  Associations of Cough Prevalence with Ambient Polycyclic Aromatic Hydrocarbons, Nitrogen and Sulphur Dioxide: A Longitudinal Study. Anyenda EO, Higashi T, Kambayashi Y, Nguyen TT, Michigami Y, Fujimura M, Hara J, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Yamada Y, Hayashi K, Hayakawa K, Nakamura H Int J Environ Res Public Health 13 8 2016/08
  •  The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan. Kitaoka M, Mitoma J, Asakura H, Anyenda EO, Nguyen TT, Hamagishi T, Hori D, Suzuki F, Shibata A, Horii M, Tsujiguchi H, Hibino Y, Kambayashi Y, Hitomi Y, Shikura N, Nakamura H Environ Health Prev Med 21 4 193-214 2016/07
  •  The Association between Activity of Daily Living and the Combination of Alzheimer’s Disease and Cataract in Elderly Requiring Nursing Care. Hamagishi T, Inagawa T, Kambayashi Y, Tsujiguchi H, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Hori D, Enoch Olando Anyenda, Nguyen Thi Thu Thao, Hibino Y, Hayashi K, Shibata A, Sagara T, Okochi J, Takamoku K, Hatta K, Konoshita T, Nakamura H Health 8 10 994-1003 2016/07
  •  Combined Analysis of IFN-γ, IL-2, IL-5, IL-10, IL-1RA and MCP-1 in QFT Supernatant Is Useful for Distinguishing Active Tuberculosis from Latent Infection.  Suzukawa M, Akashi S, Nagai H, Nagase H, Nakamura H, Matsui H, Hebisawa A, Ohta K PLoS One 11 4 e0152483 2016/04
  •  Association between Smoking Status and Obesity in a Nationwide Survey of Japanese Adults. Watanabe T, Tsujino I, Konno S, Ito YM, Takashina C, Sato T, Isada A, Ohira H, Ohtsuka Y, Fukutomi Y, Nakamura H, Kawagishi Y, Okada C, Hizawa N, Taniguchi M, Akasawa A, Nishimura M PLoS One 11 3 e0148926 2016/03
  •  Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Nagata Y, Teramoto R, Fujino N, Nomura A, Tada H, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M, Hayashi K Am J Cardiol. 117 3 443-449 2016/02
  •  Oxytocin for Male Subjects with Autism Spectrum Disorder and Comorbid Intellectual Disabilities: A Randomized Pilot Study Munesue T, Nakamura H, Kikuchi M, Miura Y, Takeuchi N, Anme T, Nanba E, Adachi K, Tsubouchi K, Sai Y, Miyamoto K, Horike S, Yokoyama S, Nakatani H, Niida Y, Kosaka H, Minabe Y, Higashida H Front Psychiatry 7 2 2016/01
  •  Prevalence of Chronic Pain, Especially Headache, and Relationship with Health-Related Quality of Life in Middle-Aged Japanese Residents. Mitoma J, Kitaoka M, Asakura H, Anyenda EO, Hori D, Nguyen TT, Hamagishi T, Hayashi K, Suzuki F, Shimizu Y, Tsujiguchi H, Kambayashi Y, Hibino Y, Konoshita T, Sagara T, Shibata A, Nakamura H Health 8 116-124 2016/01
  •  A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism. Nguyen TT, Higashi T, Kambayashi Y, Anyenda EO, Michigami Y, Hara J, Fujimura M, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Hibino Y, Konoshita T, Nakamura H Int J Environ Res Public Health 13 1 2016/01
  •  Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Hayashi K, Fujino N, Oka R, Nomura A, Nagata Y, Hodatsu A, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M J Cardiovasc Electrophysiol 26 10 1081-1087 2015/10
  •  Genomic Disease Outcome Consortium (G-DOC) Study Investigators: A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. Makino Y, Konoshita T, Omori A, Maegawa N, Nakaya T, Ichikawa M, Yamamoto K, Wakahara S, Ishizuka T, Onoe T, Nakamura H PLoS One 10 9 e0137469 2015/09
  •  Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. Ooi A, Oyama T, Nakamura R, Tajiri R, Ikeda H, Fushida S, Nakamura H, Dobashi Y Mod Pathol 28 6 861-871 2015/06
  •  Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging. Nagata Y, Konno T, Fujino N, Hodatsu A, Nomura A, Hayashi K, Nakamura H, Kawashiri MA, Yamagishi M Can J Cardiol 31 6 702-708 2015/06
  •  Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial. Noguchi-Shinohara M, Ono K, Hamaguchi T, Iwasa K, Nagai T, Kobayashi S, Nakamura H, Yamada M PLoS One 10 5 e0126422 2015/05
  •  Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study. Yoshita M, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakajima K, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Samuraki M, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamasaki J, Yamashina S, Yamada M PLoS One 10 3 e0120540 2015/03
  •  Fragmented QRS predicts heart failure progression in patients with hypertrophic cardiomyopathy.  Nomura A, Konno T, Fujita T, Tanaka Y, Nagata Y, Tsuda T, Hodatsu A, Sakata K, Nakamura H, Kawashiri MA, Fujino N, Yamagishi M, Hayashi K Circ J 79 1 136-143 2015/01
  •  Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. Fukutomi Y, Taniguchi M, Nakamura H, Akiyama K Allergy 69 10 1405-1411 2014/11
  •  Exacerbation of daily cough and allergic symptoms in adult patients with chronic cough by Asian dust: A hospital-based study in Kanazawa. Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakanishi S, Yoshizaki T, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Hitomi Y, Nakamura H Atmospheric Environment 97 537-543 2014/11
  •  Long-term Heat Exposure Prevents Hypoxia-Induced Apoptosis in Mouse Fibroblast Cells. Sugimoto N, Shido O, Matsuzaki K, Katakura M, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Nakamura H, Koizumi S, Yachie A, Umehara H Cell Biochem Biophys 70 1 301-307 2014/09
  •  Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study.  Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakai S, Honda Y, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Anyenda EO, Hitomi Y, Nakamura H Atmospheric Environment 92 506-513 2014/08
  •  High sensitivity of late gadolinium enhancement for predicting microscopic myocardial scarring in biopsied specimens in hypertrophic cardiomyopathy. Konno T, Hayashi K, Fujino N, Nagata Y, Hodatsu A, Masuta E, Sakata K, Nakamura H, Kawashiri MA, Yamagishi M PLoS One 9 7 e101465 2014/07
  •  A novel coronary active perfusion system using a conventional intra-aortic balloon pump for off-pump coronary artery bypass grafting. Kiuchi R, Tomita S, Yamaguchi S, Nishida Y, Ohtake H, Nakamura H, Watanabe G J Thorac Cardiovasc Surg 148 1 304-310 2014/07
  •  Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline.  Noguchi-Shinohara M, Yuki S, Dohmoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M PLoS One 9 5 e96013. 2014/05
  •  Preventive effects of ramelteon on delirium: a randomized placebo-controlled trial. Hatta K, Kishi Y, Wada K, Takeuchi T, Odawara T, Usui C, Nakamura H, for the DELIRIA-J Group JAMA Psychiatry 71 4 397-403 2014/04
  •  Theobromine, the Primary Methylxanthine Found in Theobroma cacao, Prevents Malignant Glioblastoma Proliferation by Negatively Regulating Phosphodiesterase-4, Extracellular Signal-regulated Kinase, Akt/mammalian Target of Rapamycin Kinase, and Nuclear Factor-Kappa B. Sugimoto N, Miwa S, Hitomi Y, Nakamura H, Tsuchiya H, Yachie A Nutr Cancer 66 3 419-423 2014/04
  •  Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study. Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, Tsuchida K, Oshima Y, Uchimura N, Akaho R, Watanabe A, Taira T, Nishimura K, Hashimoto N, Usui C, Nakamura H Int J Geriatr Psychiatry 29 3 253-262 2014/03
  •  Myasthenia gravis: Predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan.  Iwasa K, Yoshikawa H, Samuraki M, Shinohara M, Hamaguchi T, Ono K, Nakamura H, Yamada M J Neuroimmunol 267 1-2 97-101 2014/02
  •  The predictive value of a change in natural killer cell activity for delirium. Hatta K, Kishi Y, Takeuchi T, Wada K, Odawara T, Usui C, Machida Y, Nakamura H, for the DELIRIA-J Group Prog Neuropsychopharmacol Biol Psychiatry 48 26-31 2014/01
  •  The possibility that requiring high-dose olanzapine cannot be explained by pharmacokinetics in the treatment of acute-phase schizophrenia. Hatta K, Takebayashi H, Sudo Y, Katayama S, Kasuya M, Shirai Y, Morikawa F, Nakase R, Nakamura M, Ito S, Kuga H, Nakamura M, Ohnuma T, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group Psychiatry Res 210 2 396-401 2013/12
  •  The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale: reliability and validity. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Itoh K, Yamano Y, Nakamura H, Nakajima T, Nishioka K Mod Rheumatol 23 5 846-850 2013/09
  •  Vulnerability to traumatic stress in fibromyalgia patients: 19 months follow-up after the Great East Japan Disaster. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K Arthritis Res Ther 15 5 R130 2013/09
  •  Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics. Kimura H, Dobashi Y, Nojima T, Nakamura H, Yamamoto N, Tsuchiya H, Ikeda H, Sawada-Kitamura S, Oyama T, Ooi A Int J Clin Exp Pathol 6 7 1306-1316 2013/06
  •  Targeted activation of PKA and Epac promotes glioblastoma regression in vitro. Sugimoto N, Miwa S, Tsuchiya H, Hitomi Y, Nakamura H, Yachie A, Koizumi S Mol Clin Oncol 1 2 281-285 2013/03
  •  Decreased activity of daily living produced by the combination of Alzheimer's disease and lower limb fracture in elderly requiring nursing care. Inagawa T, Hamagishi T, Takaso Y, Hitomi Y, Kambayashi Y, Hibino Y, Shibata A, Ngoc NT, Okochi J, Hatta K, Takamuku K, Konoshita T, Nakamura H Environ Health Prev Med 18 16-23 2013/01
  •  The differences in the involvements of loci of promoter region and Ile50Val in interleukin-4 receptor α chain gene between atopic dermatitis and Japanese cedar pollinosis. Tanaka T, Hitomi Y, Kambayashi Y, Hibino Y, Fukutomi Y, Shibata S, Sugimoto S, Hatta K, Eboshida A, Konoshita T, Nakamura H 61 1 57-63 2012/03
  •  Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy. Usui C, Hatta K, Doi N, Kubo S, Kamigaichi R, Nakanishi A, Nakamura H, Hattori N, Arai H PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 35 7 1704-1708 2011/08
  •  Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells. Sugimoto N, Miwa S, Ohno-Shosaku T, Tsuchiya H, Hitomi Y, Nakamura H, Tomita K, Yachie A, Koizumi S NEUROSCIENCE LETTERS 497 1 55-59 2011/06
  •  The relationship between social capital and self-rated health in a Japanese population Hibino Y, Takaki J, Ogino K, Kambayashi Y, Hitomi Y, Shibata A, Nakamura H 2011/05
  •  The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Ito K, Yamano Y, Nakamura H, Nakajima T, Nishioka K 22 1 40-44 2011/05
  •  Difference in early prediction of antipsychotic non-response between risperidone and olanzapine in the treatment of acute-phase schizophrenia. Hatta K, Otachi T, Sudo Y, Hayakawa T, Ashizawa Y, Takebayashi H, Hayashi N, Hamakawa H, Ito S, Nakase R, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group. SCHIZOPHRENIA RESEARCH 128 127-135 2011/03
  •  Rhinoconjunctival sensitization to hydrolyzed wheat protein in facial soap can induce wheat-dependent exercise-induced anaphylaxis. Fukutomi Y, Itagaki Y, Taniguchi M, Saito A, Yasueda H, Nakazawa T, Hasegawa M, Nakamura H, Akiyama K JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 127 2 531-533 2011/02
  •  C-reactive protein is associated with cigarette smoking-induced hyperfiltration and proteinuria in an apparently healthy population. Sauriasari R, Sakano N, Wang DH, Takaki J, Takemoto K, Wang B, Sugiyama H, Sato Y, Takigawa T, Takahashi N, Kanbara S, Hitomi Y, Nakamura H, Ogino K HYPERTENSION RESEARCH 33 1129–1136 2010/11
  •  A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker. Konoshita T, Makino Y, Kimura T, Fujii M, Wakahara S, Arakawa K, Inoki I, Nakamura H, Miyamori I, Genomic Disease Outcome Consortium Study Investigators JOURNAL OF HYPERTENSION 28 10 2156-2160 2010/10
  •  Relationship Between Sense of Coherence and Depression among Workers: A Large-scale Epidemiologic Survey in Tsukuba Science City. Umeda T, Sasahara S, Tomotsune Y, Yoshino S, Usami K, Haoka T, Ohi Y, Nakamura H, Matsuzaki I J Phys Fit Nutri Immunol. 20 1 3-10 2010/10
  •  Association between altered systemic inflammatory interleukin-1beta and natural killer cell activity and subsequently agitation in patients with alzheimer disease. Higuchi M, Hatta K, Honma T, Hitomi YH, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Nakamura H INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY 25 6 604-611 2010/06
  •  A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies: haloperidol versus flunitrazepam. Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Furuta K, Kawabata T, Hirata T, Usui C, Nakamura H, Sawa Y PSYCHIATRY RESEARCH 178 1 182-185 2010/06
  •  Nationwide Cross-Sectional Population-Based Study on the Prevalences of Asthma and Asthma Symptoms among Japanese Adults. Fukutomi Y, Nakamura H, Kobayashi F, Taniguchi M, Konno S, Nishimura M, Kawagishi Y, Watanabe J, Komase Y, Akamatsu Y, Okada C, Tanimoto Y, Takahashi K, Kimura T, Eboshida A, Hirota R, Ikei J, Odajima H, Nakagawa T, Akasawa A, Akiyama K INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 153 3 280-287 2010/05
  •  Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K, Arai H Arthritis Res Ther. 12 2 R64 2010/04
  •  Anti-inflammatory effects of limonene from yuzu (Citrus junos Tanaka) essential oil on eosinophils. Hirota R, Roger NN, Nakamura H, Song HS, Sawamura M, Suganuma N JOURNAL OF FOOD SCIENCE 75 3 H87-92 2010/04
  •  Open wards versus locked wards of general hospitals in the treatment of psychiatric patients with medical comorbidities: a cross-sectional study in Tokyo. Hatta K, Usui C, Nakamura H, Kurosawa H, Arai H PSYCHIATRY AND CLINICAL NEUROSCIENCES 64 1 52-6 2010/02
  •  The association of sense of coherence and coping profile with stress among research park city workers in Japan. Tomotsune Y, Sasahara S, Umeda T, Hayashi M, Usami K, Yoshino S, Kageyama T, Nakamura H, Matsuzaki I INDUSTRIAL HEALTH 47 6 664-672 2009/12
  •  Common risk factors for changes in body weight and psychological well-being in Japanese male middle-aged workers. Sagara T, Hitomi Y, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Ogino K, Hatta K, Nakamura H Environ Health Prev Med. 14 319-327 2009/11
  •  Low serum secretory immunoglobulin A level and sense of coherence score at an early gestational stage as indicators for subsequent threatened premature birth. Sekizuka N, Sakai A, Shimada K, Tabuchi N, Kameda Y, Nakamura H Environ Health Prev Med. 14 5 276-283 2009/09
  •  Effectiveness of second-generation antipsychotics with acute-phase schizophrenia. Hatta K, Sato K, Hamakawa H, Takebayashi H, Kimura N, Ochi S, Sudo Y, Asukai N, Nakamura H, Usui C, Kawabata T, Hirata T, Sawa Y SCHIZOPHRENIA RESEARCH 113 49-55 2009/08
  •  Exploring factors associated with the incidence of sexual harassment of hospital nurses by patients. Hibino Y, Hitomi Y, Kambayashi Y, Nakamura H Journal of Nursing Scholarship 41 2 124-131 2009/06
  •  Medical and psychiatric comorbidity in psychiatric beds in general hospitals: a cross-sectional study in Tokyo. Hatta K, Nakamura H, Usui C, Kobayashi T, Kamijo Y, Hirata T, Awata S, Kishi Y, Arai H, Kurosawa H PSYCHIATRY AND CLINICAL NEUROSCIENCES 63 3 329-335 2009/06
  •  Perceived stress, severity of asthma, and quality of life in young adults with asthma. Kimura T, Yokoyama A, Kohno N, Nakamura H, Eboshida A Allergology International 58 1 71-79 2009/03
  •  Health impact of disaster-related stress on pregnant women living in the affected area of the Noto Peninsula earthquake in Japan. Hibino Y, Takaki J, Kambayashi Y, Hitomi Y, Sakai A, Sekizuka N, Ogino K, Nakamura H PSYCHIATRY AND CLINICAL NEUROSCIENCES 63 1 107-115 2009/02
  •  Efficient assay for total antioxidant capacity in human plasma using a 96-well microplate. Kambayashi Y, Binh NT, W Asakura H, Hibino Y, Hitomi Y, Nakamura H, Ogino K JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 44 1 46-51 2009/01
  •  Preparation and Characterization of a Polyclonal Antibody against Brominated Protein. Kambayashi Y, Ogino K, Takemoto K, Imagama T, Takigawa T, Kimura S, Hibino Y, Hitomi Y, Nakamura H JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 44 1 95-103 2009/01
  •  Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma. Ooi A, Suzuki S, Nakazawa K, Itakura J, Imoto I, Nakamura H, Dobashi Y ANTICANCER RESEARCH 29 1 19-26 2009/01
  •  Disturbed Homeostasis in Patients with Acute Psychosis. Hatta K, Chie Usui, Nakamura H Curr Psychiatry Rev. 4 4 190-195 2008/11
  •  Olanzapine orally disintegrating tablet vs. risperidone oral solution in the treatment of acutely agitated psychotic patients. Gen Hosp Psychiatry. Hatta K, Kawabata T, Yoshida K, Hamakawa H, Wakejima T, Furuta K, Nakamura M, Hirata T, Usui C, Nakamura H, Sawa Y GENERAL HOSPITAL PSYCHIATRY 30 4 367-371 2008/07
  •  In vitro toxicity evaluation of diesel exhaust particles on human eosinophilic cell. Hirota R, Akimaru K, Nakamura H. TOXICOLOGY IN VITRO 22 4 988-994 2008/06
  •  Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms. Hatta K, Miyakawa K, Ota T, Usui C, Nakamura H, Arai H. JOURNAL OF ECT 23 4 233-235 2007/12
  •  Relationship between mental health of Japanese residents and the quality of medical service. Yoshino S, Sasahara S, Maeno T, Kitaoka-Higashiguchi K, Tomotsune Y, Taniguchi K, Tomita E, Usami K, Haoka T, Nakamura H, Matsuzaki I. J Phys Fit Nutri Immunol. 7 1 3-11 2007/08
  •  Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis. Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Ogino K, Akimaru K, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 142 4 329-334 2007/03
  •  Psychological factors including sense of coherence and some lifestyles are related to General Health Questionnaire-12 (GHQ-12) in elderly workers in Japan. Matsuzaki I, Sagara T, Ohshita Y, Nagase H, Ogino K, Eboshida A, Sasahara S, Nakamura H. Environ Health Prev Med 12 2 71-77 2007/03
  •  Association between Physical Restraint and Drug-Induced Liver Injury. Hatta K, Shibata N, Ota T, Usui C, Ito M, Nakamura H, Arai H. NEUROPSYCHOBIOLOGY 56 4 180-184 2007
  •  What affects the General Health Questionnaire score among former Hansen's Disease patients in leprosarium? J Phys Fit Nutri Immunol 15 2 69-81 2005/12
  •  Influences of the stress coping ability of supervisors on the stress situation of their subordinates. Tatsukawa H, Sasahara S, Yoshino S, Tomotsune Y, Taniguchi K, Nakamura H, Matsuzaki I. J Phys Fit Nutri Immunol 15 2 82-87 2005/12
  •  Psychological well-being and associated factors among elderly Hansen's disease patients in leprosaria. Kataoka M, Nakamura H. Environ Health Prevent Med 10 4 201-207 2005/07
  •  Eradication of epstein-barr virus episome and associated inhibition of infected tumor cell growth by adenovirus vector-mediated transduction of dominant-negative EBNA1. Nasimuzzaman M, Kuroda M, Dohno S, Yamamoto T, Iwatsuki K, Matsuzaki S, Mohammad R, Kumita W, Mizuguchi H, Hayakawa T, Nakamura H, Taguchi T, Wakiguchi H, Imai S. MOLECULAR THERAPY 11 4 578-590 2005/04
  •  Increasing prevalence of Japanese cedar pollinosis: a meta-regression analysis. Kaneko Y, Motohashi Y, Nakamura H, Endo T, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 136 4 365-371 2005/04
  •  A study on the mechanisms of depressive tendency in patients with cedar pollinosis focusing on the sense of coherence (SOC) as a stress-coping skill. Hattori K, Sasahara S, Nakamura H, Ozasa K, Endo T, Imai T, Ide T, Honda Y, Hatta K, Motohashi Y, Eboshida A, Matsuzaki I. J Phys Fit Nutr Immnol 14 3 188-194 2004/12
  •  Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with Japanese cedar pollinosis. Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Ogino K, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 135 1 40-43 2004/09
  •  Physiological involvement of placental endothelin-1 and prostaglandin F2alpha in uteroplacental circulatory disturbance in pregnant rats exposed to heat stress. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 82 4 225-230 2004/04
  •  Higher sense of coherence as a psychological factor responsible for elevated natural killer cell activity in patients with cedar pollinosis. Nakamura H, Matsuzaki I, Sasahara S, Hatta K, Endo T, Imai T, Ozasa K, Motohashi Y, Ogino K, Eboshida A. J Phys Fit Nutri Immunol 14 1 25-32 2004/04
  •  Induction of eosinophil peroxidase and nitrotyrosine formation in a human leukemia cell line, EoL-1. Cell Biochem Funct 22 2 105-112 2004/03
  •  Elevated serum nitric oxide metabolites in hypertensives J Phys Fit Nutri Immunol 11 34-39 2001/12
  •  Catalase catalyzes nitrotyrosine formation from sodium azide and hydrogen peroxide Free Radic Res 35 735-747 2001/12
  •  Plasma VEGF concentration can predict the tumor angiogenic capacity in non-small cell lung cancer Oncol Rep 8 1097-1102 2001/09
  •  Natural killer cell activity and its related psychological factor, sense of coherence in male smokers J Occup Health 43 191-198 2001/07
  •  The association between intravenous haloperidol and prolonged QT interval J Cli Psychopharmacol 21 257-261 2001/06
  •  Mental health of scientific researchers. I. Characteristics of job stress among scientific researchers working at a research park in Japan Int Arch Occup Environ Health 74 199-205 2001/04
  •  Involvement of central, but not placental corticotropin releasing hormone (CRH) in heat stress-induced immunosuppression during pregnancy BRAIN BEHAVIOR AND IMMUNITY 15 43-53 2001/03
  •  Heat produces uteroplacental circulatory disturbance in pregnant rats through action of corticotropin releasing hormone (CRH) PLACENTA 21 510-515 2000/07
  •  Prolonged QT interval in acute psychotic patients PSYCHIATRY RESEARCH 17 279-85 2000/07
  •  Uteroplacental circulatory disturbance in pregnant rats exposed to microwaves through actions of prostaglandin F2α REPRODUCTIVE TOXICOLOGY 14 235-240 2000/05
  •  Prolonged upper airway instability in the parenteral use of benzodiazepine with levomepromazine JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 20 99-101 2000/02
  •  A retrospective study of occular toxocariasis in Japan: correlation with antibody prevalence and ophthalmological findings of patients with uveitis JOURNAL OF HELMINTHOLOGY 73 357-361 1999/12
  •  Association between QOL and its related factors including stress and mother-child relationship in adolescent children Hokuriku J Public Health 25 72-78 1999/11
  •  Sodium azide inhibits nitric oxide production by rat neutrophils J Phys Fit Nutr Immunol 9 103-108 1999/09
  •  Laboratory findings in acute schizophrenia: relevance to medical management on emergency admission Gen Hosp Psychiatry 21 220-227 1999/06
  •  Natural killer (NK) cell activity and NK cell subsets in workers with a tendency of burnout J Psychosom Res 46 569-578 1999/06
  •  The predictive value of benzodiazepine tolerance in persistently aggressive schizophrenia NEUROPSYCHOBIOLOGY 39 0 196-199 1999/05
  •  Hypokalemia and agitation in acute psychotic patients Psychiat Res 86 85-88 1999/04
  •  Opioid peptides mediate heat stress-induced immunosuppression during pregnancy Am J Physiol 274 R672-R676 1998/03
  •  Natural killer cell activity reduced by microwave exposure during pregnancy is mediated by opioid systems Environ Res 79 106-113 1998/11
  •  Effects of exposure to microwaves on cellular immunity and placental steroids in pregnant rats Occup Environ Med 54 676-680 1997/09
  •  Central administration of interleukin-1β reduces natural killer cell activity in non-pregnant rats, but not in pregnant rats PSYCHONEUROENDOCRINOLOGY 23 651-659 1998/08
  •  A risk for obstruction of the airways in the parenteral use of levomepromazine with benzodiazepine PHARMACOPSYCHIATRY 31 0 126-130 1998/07
  •  Abnormal physiological conditions in acute schizophrenic patients on emergency admission: dehydration, hypokalemia, leukocytosis and elevated serum muscle enzymes Eur Arch Psychiatr Clin Neurosci 248 180-188 1998
  •  Involvement of central neurotensin in thermoregulatory and neuroimmune function in pregnant rats exposed to heat Brain Behav Immun 11 141-152 1997/06
  •  Inhibitory effect of pregnancy on stress-induced immunosuppression through corticotropin releasing hormone (CRH) and dopaminergic systems J Neuroimmunol 75 1-8 1997/05

Conference Presentations

Arts and Fieldwork

Patent

Theme to the desired joint research

○Epidemiologic study on microwave effects
○Development of Indicators for Work Stress

Grant-in-Aid for Scientific Research

○「環境中化学物質による気管支喘息症の中心的役割としてのエクソソームとそのmiRNA」(2019-2022) 
○「鼻茸をはじめとする慢性副鼻腔炎の危険因子としての環境中化学物質に関する疫学研究」(2019-2021) 
○「一般住民への食生活介入の高尿酸血症及び慢性腎臓病に対する1次予防効果の検討」(2019-2023) 
○「過酸化された情報伝達物質である脂質の気管支喘息への関与および環境化学物質の影響」(2019-2021) 
○「大規模疫学データによる森林浴ガイドラインの開発:生活習慣病予防と睡眠改善」(2018-2020) 
○「ウエアラブルセンサーを用いた思春期うつ状態の早期発見」(2018-2020) 
○「多環芳香族炭化水素類の複合反応と疾病との関係に関する開拓研究」(2017-2021) 
○「大気粉塵中遷移金属による喘息患者の症状悪化機構の解明」(2017-2019) 
○「環境及び併存疾患がIgG4関連疾患の発症進展に与える影響」(2017-2019) 
○「メラトニン・オレキシン神経伝達を視点にしたせん妄予防,治療,病態評価の総合研究」(2017-2019) 
○「住環境が脳・循環器・呼吸器・運動器に及ぼす影響実測と疾病・介護予防便益評価」(2017-2021) 
○「食物アレルギーにおけるリンパ球と腸内細菌叢のエピジェネティクスの解明による予防法」(2015-2017) 
○「食物アレルギーの観点から自閉傾向の新指標と予防法を開発する」(2015-2017) 
○「大気粉塵中化学物質の喘息患者に対する健康影響評価およびその予防法の開発」(2014-2016) 
○「腸内細菌叢マイクロバイオームの解析を用いたアレルギーと肥満の新しい予防法の開発」(2013-2015) 
○「多環芳香族炭化水素類による喘息増悪への酸化ストレスの関与」(2013-2015) 
○「ヒト末梢血・培養細胞を用いた大気汚染物質の免疫毒性評価法の開発」(2013-2015) 
○「大陸から飛来する黄砂のアレルギー症重症化への影響評価とその予防」(2013-2017) 
○「自閉症傾向の早期発見のための新しい指標と予防法の開発―食とアレルギーとの関連から」(2013-2016) 
○「高輝度蛍光タンパクを用いた「運動レポーター動物」の作出と骨格筋の機能解析」(2012-2013) 
○「アレルギー疾患エピジェネティクスにおけるウイルス感染の役割解明とその予防法の開発」(2011-2013) 
○「せん妄の治療,予防,医療安全に関する実証研究」(2011-2014) 
○「ディーゼル排気ガスおよび黄砂由来化学物質暴露のバイオマーカー探索と健康影響評価」(2010-2012) 
○「「ビタミンC生合成能を持つマウス」を用いた酸化ストレスとビタミンC代謝の研究」(2010-2012) 
○「インフルエンザウイルスとスギ花粉T細胞エピトープを用いた新しいリポソームワクチン」(2010-2012) 
○「運動の見える新規レポーター動物を用いた、運動・姿勢制御と骨格筋機能の解析」(2009-2011) 
○「RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法」(2008-2010) 
○「「子どものこころ」の発達に及ぼす食育のあり方に関するコホート研究」(2008-2011) 
○「骨格筋活動を見る:運動感受性遺伝子のプロモーターを用いた運動レポーター動物の作出」(2007-2008) 
○「SNP解析を用いた腎細胞癌感受性遺伝子の解析に関する研究」(2006-2007) 
○「新しい好酸球活性化バイオマーカーの開発と喘息のリスク評価」(2006-2007) 
○「環境中物質と好酸球関連蛋白遺伝子の相互作用解明によるアレルギー疾患の予防」(2005-2007) 
○「二酸化窒素様活性窒素種の心血管系組織からの発生機序とその制御に関する研究」(2002-2004) 
○「マイクロ波による子宮胎盤循環及び胎盤機能障害に対する胎児側防御機構の解明」(2001-2002) 
○「マイクロ波超低レベル発生試験解析システムの開発」(2000-2001) 
○「胃・小腸粘膜防御におけるニトロチロシン陽性細胞の動態と予防医学的検討」(2000-2001) 
○「新しい二酸化窒素反応性窒素様種の生体内発生とその防御機構の解明」(1999-2001) 
○「マイクロ波の低レベル変調波による妊娠母胎の神経内分泌免疫系への影響」(1997-1998) 
○「物理的環境ストレスによる胎盤CRH及びオピオイド受容体遺伝子発現とその生理的意義」(1999-2000) 
○「物理的環境刺激による神経免疫系への影響に関する研究」(1995-1996) 
○「入院老人の転倒予防に関する看護的研究」(1994-1995) 
○「全身振動による流産発生機序に関する研究」(1993-1993) 
○「衝撃型振動の手腕系末梢循環動態に及ぼす影響に関する研究」(1992-1993) 
○「事務所衛生基準規則に関する研究-妥当性と国際基準との調和(労災疾病臨床研究事業)」(2019-2021) 
○「慢性疼痛診療システムの均てん化と痛みセンター診療データベースの活用による医療向上を目指す研究(慢性の痛み政策研究事業)」(2019-2021) 
○「慢性の痛み診療・教育となるシステム構築に関する研究」(2018-2018) 
○「慢性の痛み診療・教育の基盤となるシステム構築に関する研究」(2015-2017) 
○「慢性の痛み診療の基盤となる情報の集約とより高度な診療のための医療システム構築に関する研究(慢性の痛み対策 研究事業)」(2013-2014) 
○「難治性疼痛の実態の解明と対応策の開発に関する研究(慢性の痛み対策 研究事業)」(2011-2012) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2011-) 
○「成人独自のアナフィラキシーの実態と病態に関する研究(免疫アレルギー疾患等予防・治療 研究事業)」(2011-2011) 
○「脊髄障害性疼痛症候群の実態の把握と病態の解明に関する研究(難治性疾患克服 研究事業)」(2010-2011) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2010-) 
○「難治性慢性疼痛の実態と病態の解明に関する研究(障害者対策総合 研究事業)」(2010-) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2009-) 
○「気管支喘息難治・重症化の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2008-) 
○「気管支喘息難治・重症化の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2007-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2006-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2005-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2004-) 

Classes (Bachelors)

○Public Health(2019)
○Introduction to Region-studies(2019)
○Lecture on Life in Campus and Society(2019)
○Public Health(2018)
○Introduction to Region-studies(2018)
○Lecture on Life in Campus and Society(2018)
○Public Health(2017)
○Introduction to Region-studies(2017)
○Lecture on Life in Campus and Society(2017)
○Public Health(2016)
○Public Health(2016)
○Introduction to Region-studies(2016)
○Lecture on Life in Campus and Society(2016)

Classes (Graduate Schools)

○Environment and Health -Introductory(2019)
○Seminar of Medical Statistics(2019)
○Field Practices for Cohort Study in Rural Areas(2019)
○Hygiene and Public Health(2019)
○Basic Training on Medical Researches(2019)
○Bio-Ethics(2019)
○Preventive Medicine(2019)
○Intensive Lectures on Medical Researches(2019)
○Medical Statistics and Epidemiology(2019)
○The Human Body in Health and Disease Curriculum 2(2019)
○Itemized Lectures on Medical Statictics(2019)
○Environmental Health and Preventive Medicine(2019)
○Environment and Heredity(2019)
○Training Program for Russia-East Asia Innovative Leaders in Preemptive Medicine(Doctoral Course)(2019)
○Introduction to Basic Medical Science(2018)
○Environment and Heredity(2018)
○Environmental Health and Preventive Medicine(2018)
○Seminar of Medical Statistics(2018)
○Medical Statistics and Epidemiology(2018)
○Itemized Lectures on Medical Statictics(2018)
○Environment and Health -Introductory(2018)
○Environment and Health -Introductory(2018)
○Bio-Ethics(2018)
○Preventive Medicine(2018)
○Field Practices for Cohort Study in Rural Areas(2018)
○Environmental Health and Preventive Medicine(2017)
○Medical Statistics and Epidemiology(2017)
○Environment and Heredity(2017)
○Environment and Health(2017)
○Itemized Lectures on Medical Statictics(2017)
○Seminar of Medical Statistics(2017)
○Preventive Medicine(2017)
○Bio-Ethics(2017)
○Hygiene and Public Health(2017)
○Environment and Health -Introductory(2017)
○Introduction to Basic Medical Science(2016)
○Medical Statistics and Epidemiology(2016)
○Preventive Medicine(2016)
○Hygiene and Public Health(2016)
○Environment and Health(2016)
○Environment and Heredity(2016)
○Seminar of Medical Statistics(2016)
○Itemized Lectures on Medical Statictics(2016)
○Preventive Medicine(2016)
○Environment and Health -Introductory(2016)
○Environmental Health and Preventive Medicine(2016)
○Bio-Ethics・Research-Ethics(2016)
○Intensive Lectures on Medical Researches(2011)
○Basic Training on Medical Researches(2011)

International Project

International Students

Lecture themes

○Prevention of Allergy

Others (Social Activities)

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