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Researcher Information

last modified:2019/04/22

Professor NAKAMURA Hiroyuki

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Faculty, Affiliation

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences

College and School Educational Field

Division of Medical Sciences, Graduate School of Medical Science
Division of Environmental Science, Graduate School of Medical Scienc
School of Medicine, College of Medical, Pharmaceutical and Health Sciences

Laboratory

Environmental and Preventive Medicine TEL:076-265-2218 FAX:076-234-4233

Academic Background

【Academic background(Doctoral/Master's Degree)】
Kanazawa University Doctor Completed
【Academic background(Bachelor's Degree)】
Kanazawa University
【Degree】
Medical Doctor

Career

Year & Month of Birth

Academic Society


The Japanese Society for Hygiene
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Japan Society For Occupational Health
Japan Society For Occupational Health
The Japanese Society Of Health And Human Ecology
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International Commission of Occupational Health
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Japan Epidemiological Association
Japanese Society Of Preventive Medicine
Japan Society Of Adolescentology
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Award

○-(1990)
○-(1991)
○-(2004)
○-(2004)
○-(2004)

Specialities

Hygiene and public health

Speciality Keywords

Public health, Preventive medicine, Industrial medicine, epidemiology, molecular epidemiology, Environmental health, Allergy, stress, Electromagnetics, QOL

Research Themes

Effects of Physical Environmental Factors

We have examined the biological effects of physical environmental factors, such as vibration, noise, low-frequency sound, heat, and electromagnetic waves. We clarified the central and peripheral mechanisms underlying gastric ulcers and miscarriages induced by vibration and the physiological pathogenetic mechanism of vibration-induced white finger disease. In addition, as regards the social problem of the biological impact of microwaves in the current environment of satellite communications, we identified the role of brain opioids during exposure to microwaves in relation to cellular immune function. We also discovered that placenta CRH is related to the adjustment of placenta circulatory function. We propose that although the current exposure standards are within a safe range, there should be continued systematic investigation on the impact of microwaves on a fetus.

Environmental Factors and Molecular Epidemiology on Allergic Diseases

We clarified the effects of environmental factors, especially chemical substances in the environment, on allergic diseases. Simultaneously, we also conducted applied research, such as development of a filter to prevent diesel particles from inducing allergic diseases. We have implemented molecular epidemiological research concerning the environment and genetics of cedar pollen allergy and asthma and identified the susceptibility gene that leads to development in interaction with the environment. We aim to use this research to devise individualized methods of prevention.

Epidemiology on diseases induced by factors of life-styles including nutrition and stress since infancy

Primary prevention of lifestyle diseases and diseases related to nutritional excesses or deficiencies requires attention to propser nutritional intake and lifestyle habits from childhood. Additionally, allergic diseases, which have been on the rise in the recent years, are a major childhook health problem, and have been found to be closely related to stress and psychological problems. This study is intended to describe the effects of various factors related to health issues, such as nutritional intake and conditions, lifestyle habits, and environmental factors, on children’s health, and to develop health education methods for the prevention of disease onset.

Books

  •  The ABC of psychiatric emergencies: aggression, body, and calmatives Elsevier Science 1999

Papers

  •  Exposure to daily ambient particulate polycyclic aromatic hydrocarbons and cough occurrence in adult chronic cough patients: A longitudinal study. Enoch Olando Anyenda, Tomomi Higashi, Yasuhiro Kambayashi, Nguyen Thi Thu Thao, Yoshimasa Michigami, Masaki Fujimura, Johsuke Hara, Hiromasa Tsujiguchi, Masami Kitaoka, Hiroki Asakura, Daisuke Hori, Yohei Yamada, Koichiro Hayashi, Kazuichi Hayakawa, Hiroyuki Nakamura Atmospheric Environment 140 34–41 2016/09
  •  Associations of Cough Prevalence with Ambient Polycyclic Aromatic Hydrocarbons, Nitrogen and Sulphur Dioxide: A Longitudinal Study. Anyenda EO, Higashi T, Kambayashi Y, Nguyen TT, Michigami Y, Fujimura M, Hara J, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Yamada Y, Hayashi K, Hayakawa K, Nakamura H Int J Environ Res Public Health 13 8 2016/08
  •  The Association between Activity of Daily Living and the Combination of Alzheimer’s Disease and Cataract in Elderly Requiring Nursing Care. Hamagishi T, Inagawa T, Kambayashi Y, Tsujiguchi H, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Hori D, Enoch Olando Anyenda, Nguyen Thi Thu Thao, Hibino Y, Hayashi K, Shibata A, Sagara T, Okochi J, Takamoku K, Hatta K, Konoshita T, Nakamura H Health 8 10 994-1003 2016/07
  •  The associations between lifestyles and mental health using the General Health Questionnaire 12-items are different dependently on age and sex: a population-based cross-sectional study in Kanazawa, Japan. Hori D, Tsujiguchi H, Kambayashi Y, Hamagishi T, Kitaoka M, Mitoma J, Asakura H, Suzuki F, Anyenda EO, Nguyen TT, Hibino Y, Shibata A, Hayashi K, Sagara T, Sasahara S, Matsuzaki I, Hatta K, Konoshita T, Nakamura H Environ Health Prev Med 2016/06
  •  Combined Analysis of IFN-γ, IL-2, IL-5, IL-10, IL-1RA and MCP-1 in QFT Supernatant Is Useful for Distinguishing Active Tuberculosis from Latent Infection.  Suzukawa M, Akashi S, Nagai H, Nagase H, Nakamura H, Matsui H, Hebisawa A, Ohta K PLoS One 11 4 e0152483 2016/04

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  •  Association between Smoking Status and Obesity in a Nationwide Survey of Japanese Adults. Watanabe T, Tsujino I, Konno S, Ito YM, Takashina C, Sato T, Isada A, Ohira H, Ohtsuka Y, Fukutomi Y, Nakamura H, Kawagishi Y, Okada C, Hizawa N, Taniguchi M, Akasawa A, Nishimura M PLoS One 11 3 e0148926 2016/03
  •  Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Nagata Y, Teramoto R, Fujino N, Nomura A, Tada H, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M, Hayashi K Am J Cardiol. 117 3 443-449 2016/02
  •  A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism. Nguyen TT, Higashi T, Kambayashi Y, Anyenda EO, Michigami Y, Hara J, Fujimura M, Tsujiguchi H, Kitaoka M, Asakura H, Hori D, Hibino Y, Konoshita T, Nakamura H Int J Environ Res Public Health 13 1 2016/01
  •  Prevalence of Chronic Pain, Especially Headache, and Relationship with Health-Related Quality of Life in Middle-Aged Japanese Residents. Mitoma J, Kitaoka M, Asakura H, Anyenda EO, Hori D, Nguyen TT, Hamagishi T, Hayashi K, Suzuki F, Shimizu Y, Tsujiguchi H, Kambayashi Y, Hibino Y, Konoshita T, Sagara T, Shibata A, Nakamura H Health 8 116-124 2016/01
  •  The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan. Kitaoka M, Mitoma J, Asakura H, Anyenda EO, Nguyen TT, Hamagishi T, Hori D, Suzuki F, Shibata A, Horii M, Tsujiguchi H, Hibino Y, Kambayashi Y, Hitomi Y, Shikura N, Nakamura H Environ Health Prev Med 2016
  •  Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy. Konno T, Hayashi K, Fujino N, Oka R, Nomura A, Nagata Y, Hodatsu A, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M J Cardiovasc Electrophysiol 26 10 1081-1087 2015/10
  •  Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. Ooi A, Oyama T, Nakamura R, Tajiri R, Ikeda H, Fushida S, Nakamura H, Dobashi Y Mod Pathol 28 6 861-871 2015/06
  •  Genomic Disease Outcome Consortium (G-DOC) Study Investigators: A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. Makino Y, Konoshita T, Omori A, Maegawa N, Nakaya T, Ichikawa M, Yamamoto K, Wakahara S, Ishizuka T, Onoe T, Nakamura H PLoS One 10 9 e0137469 2015/09
  •  Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging. Nagata Y, Konno T, Fujino N, Hodatsu A, Nomura A, Hayashi K, Nakamura H, Kawashiri MA, Yamagishi M Can J Cardiol 31 6 702-708 2015/06
  •  Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial. Noguchi-Shinohara M, Ono K, Hamaguchi T, Iwasa K, Nagai T, Kobayashi S, Nakamura H, Yamada M PLoS One 10 5 e0126422 2015/05
  •  Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study. Yoshita M, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakajima K, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Samuraki M, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamasaki J, Yamashina S, Yamada M PLoS One 10 3 e0120540 2015/03
  •  Fragmented QRS predicts heart failure progression in patients with hypertrophic cardiomyopathy.  Nomura A, Konno T, Fujita T, Tanaka Y, Nagata Y, Tsuda T, Hodatsu A, Sakata K, Nakamura H, Kawashiri MA, Fujino N, Yamagishi M, Hayashi K Circ J 79 1 136-143 2015/01
  •  Exacerbation of daily cough and allergic symptoms in adult patients with chronic cough by Asian dust: A hospital-based study in Kanazawa. Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakanishi S, Yoshizaki T, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Hitomi Y, Nakamura H Atmospheric Environment 97 537-543 2014/11
  •  Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. Fukutomi Y, Taniguchi M, Nakamura H, Akiyama K Allergy 69 10 1405-1411 2014/11
  •  Long-term Heat Exposure Prevents Hypoxia-Induced Apoptosis in Mouse Fibroblast Cells. Sugimoto N, Shido O, Matsuzaki K, Katakura M, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Nakamura H, Koizumi S, Yachie A, Umehara H Cell Biochem Biophys 70 1 301-307 2014/09
  •  Erratum to: Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H, The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Clin Exp Nephrol 18 4 621-622 2014/08
  •  Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H, The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan Clinical impacts of albuminuria and glomerular filtration rate on renal, cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. Clin Exp Nephrol 18 4 613-620 2014/08
  •  Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study.  Higashi T, Kambayashi Y, Ohkura N, Fujimura M, Nakai S, Honda Y, Saijoh K, Hayakawa K, Kobayashi F, Michigami Y, Anyenda EO, Hitomi Y, Nakamura H Atmospheric Environment 92 506-513 2014/08
  •  High sensitivity of late gadolinium enhancement for predicting microscopic myocardial scarring in biopsied specimens in hypertrophic cardiomyopathy. Konno T, Hayashi K, Fujino N, Nagata Y, Hodatsu A, Masuta E, Sakata K, Nakamura H, Kawashiri MA, Yamagishi M PLoS One 9 7 e101465 2014/07
  •  A novel coronary active perfusion system using a conventional intra-aortic balloon pump for off-pump coronary artery bypass grafting. Kiuchi R, Tomita S, Yamaguchi S, Nishida Y, Ohtake H, Nakamura H, Watanabe G J Thorac Cardiovasc Surg 148 1 304-310 2014/07
  •  Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline.  Noguchi-Shinohara M, Yuki S, Dohmoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M PLoS One 9 5 e96013. 2014/05
  •  Theobromine, the Primary Methylxanthine Found in Theobroma cacao, Prevents Malignant Glioblastoma Proliferation by Negatively Regulating Phosphodiesterase-4, Extracellular Signal-regulated Kinase, Akt/mammalian Target of Rapamycin Kinase, and Nuclear Factor-Kappa B. Sugimoto N, Miwa S, Hitomi Y, Nakamura H, Tsuchiya H, Yachie A Nutr Cancer 66 3 419-423 2014/04
  •  Preventive effects of ramelteon on delirium: a randomized placebo-controlled trial. Hatta K, Kishi Y, Wada K, Takeuchi T, Odawara T, Usui C, Nakamura H, for the DELIRIA-J Group JAMA Psychiatry 71 4 397-403 2014/04
  •  Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study. Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, Tsuchida K, Oshima Y, Uchimura N, Akaho R, Watanabe A, Taira T, Nishimura K, Hashimoto N, Usui C, Nakamura H Int J Geriatr Psychiatry 29 3 253-262 2014/03
  •  Myasthenia gravis: Predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan.  Iwasa K, Yoshikawa H, Samuraki M, Shinohara M, Hamaguchi T, Ono K, Nakamura H, Yamada M J Neuroimmunol 267 1-2 97-101 2014/02
  •  The predictive value of a change in natural killer cell activity for delirium. Hatta K, Kishi Y, Takeuchi T, Wada K, Odawara T, Usui C, Machida Y, Nakamura H, for the DELIRIA-J Group Prog Neuropsychopharmacol Biol Psychiatry 48 26-31 2014/01
  •  The possibility that requiring high-dose olanzapine cannot be explained by pharmacokinetics in the treatment of acute-phase schizophrenia. Hatta K, Takebayashi H, Sudo Y, Katayama S, Kasuya M, Shirai Y, Morikawa F, Nakase R, Nakamura M, Ito S, Kuga H, Nakamura M, Ohnuma T, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group Psychiatry Res 210 2 396-401 2013/12
  •  Vulnerability to traumatic stress in fibromyalgia patients: 19 months follow-up after the Great East Japan Disaster. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K Arthritis Res Ther 15 5 R130 2013/09
  •  The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale: reliability and validity. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Itoh K, Yamano Y, Nakamura H, Nakajima T, Nishioka K Mod Rheumatol 23 5 846-850 2013/09
  •  Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics. Kimura H, Dobashi Y, Nojima T, Nakamura H, Yamamoto N, Tsuchiya H, Ikeda H, Sawada-Kitamura S, Oyama T, Ooi A Int J Clin Exp Pathol 6 7 1306-1316 2013/06
  •  Targeted activation of PKA and Epac promotes glioblastoma regression in vitro. Sugimoto N, Miwa S, Tsuchiya H, Hitomi Y, Nakamura H, Yachie A, Koizumi S Mol Clin Oncol 1 2 281-285 2013/03
  •  The differences in the involvements of loci of promoter region and Ile50Val in interleukin-4 receptor α chain gene between atopic dermatitis and Japanese cedar pollinosis. Tanaka T, Hitomi Y, Kambayashi Y, Hibino Y, Fukutomi Y, Shibata S, Sugimoto S, Hatta K, Eboshida A, Konoshita T, Nakamura H 2012/03
  •  Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy. Usui C, Hatta K, Doi N, Kubo S, Kamigaichi R, Nakanishi A, Nakamura H, Hattori N, Arai H PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 35 7 1704-1708 2011/08
  •  C-reactive protein is associated with cigarette smoking-induced hyperfiltration and proteinuria in an apparently healthy population. Sauriasari R, Sakano N, Wang DH, Takaki J, Takemoto K, Wang B, Sugiyama H, Sato Y, Takigawa T, Takahashi N, Kanbara S, Hitomi Y, Nakamura H, Ogino K HYPERTENSION RESEARCH 33 1129–1136 2010/11
  •  Rhinoconjunctival sensitization to hydrolyzed wheat protein in facial soap can induce wheat-dependent exercise-induced anaphylaxis. Fukutomi Y, Itagaki Y, Taniguchi M, Saito A, Yasueda H, Nakazawa T, Hasegawa M, Nakamura H, Akiyama K JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 127 2 531-533 2011/02
  •  Difference in early prediction of antipsychotic non-response between risperidone and olanzapine in the treatment of acute-phase schizophrenia. Hatta K, Otachi T, Sudo Y, Hayakawa T, Ashizawa Y, Takebayashi H, Hayashi N, Hamakawa H, Ito S, Nakase R, Usui C, Nakamura H, Hirata T, Sawa Y, for the JAST study group. SCHIZOPHRENIA RESEARCH 128 127-135 2011/03
  •  A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker. Konoshita T, Makino Y, Kimura T, Fujii M, Wakahara S, Arakawa K, Inoki I, Nakamura H, Miyamori I, Genomic Disease Outcome Consortium Study Investigators JOURNAL OF HYPERTENSION 28 10 2156-2160 2010/10
  •  Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells. Sugimoto N, Miwa S, Ohno-Shosaku T, Tsuchiya H, Hitomi Y, Nakamura H, Tomita K, Yachie A, Koizumi S NEUROSCIENCE LETTERS 497 1 55-59 2011/06
  •  Relationship Between Sense of Coherence and Depression among Workers: A Large-scale Epidemiologic Survey in Tsukuba Science City. Umeda T, Sasahara S, Tomotsune Y, Yoshino S, Usami K, Haoka T, Ohi Y, Nakamura H, Matsuzaki I J Phys Fit Nutri Immunol. 20 1 3-10 2010/10
  •  The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity. Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Ito K, Yamano Y, Nakamura H, Nakajima T, Nishioka K 2011/05
  •  The relationship between social capital and self-rated health in a Japanese population Hibino Y, Takaki J, Ogino K, Kambayashi Y, Hitomi Y, Shibata A, Nakamura H 2011/05
  •  A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies: haloperidol versus flunitrazepam. Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Furuta K, Kawabata T, Hirata T, Usui C, Nakamura H, Sawa Y PSYCHIATRY RESEARCH 178 1 182-185 2010/06
  •  Association between altered systemic inflammatory interleukin-1beta and natural killer cell activity and subsequently agitation in patients with alzheimer disease. Higuchi M, Hatta K, Honma T, Hitomi YH, Kambayashi Y, Hibino Y, Matsuzaki I, Sasahara S, Nakamura H INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY 25 6 604-611 2010/06
  •  Nationwide Cross-Sectional Population-Based Study on the Prevalences of Asthma and Asthma Symptoms among Japanese Adults. Fukutomi Y, Nakamura H, Kobayashi F, Taniguchi M, Konno S, Nishimura M, Kawagishi Y, Watanabe J, Komase Y, Akamatsu Y, Okada C, Tanimoto Y, Takahashi K, Kimura T, Eboshida A, Hirota R, Ikei J, Odajima H, Nakagawa T, Akasawa A, Akiyama K INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 153 3 280-287 2010/05
  •  Anti-inflammatory effects of limonene from yuzu (Citrus junos Tanaka) essential oil on eosinophils. Hirota R, Roger NN, Nakamura H, Song HS, Sawamura M, Suganuma N JOURNAL OF FOOD SCIENCE 75 3 H87-92 2010/04
  •  Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K, Arai H Arthritis Res Ther. 12 2 R64 2010/04
  •  Open wards versus locked wards of general hospitals in the treatment of psychiatric patients with medical comorbidities: a cross-sectional study in Tokyo. Hatta K, Usui C, Nakamura H, Kurosawa H, Arai H PSYCHIATRY AND CLINICAL NEUROSCIENCES 64 1 52-6 2010/02
  •  The association of sense of coherence and coping profile with stress among research park city workers in Japan. Tomotsune Y, Sasahara S, Umeda T, Hayashi M, Usami K, Yoshino S, Kageyama T, Nakamura H, Matsuzaki I INDUSTRIAL HEALTH 47 6 664-672 2009/12
  •  Effectiveness of second-generation antipsychotics with acute-phase schizophrenia. Hatta K, Sato K, Hamakawa H, Takebayashi H, Kimura N, Ochi S, Sudo Y, Asukai N, Nakamura H, Usui C, Kawabata T, Hirata T, Sawa Y SCHIZOPHRENIA RESEARCH 113 49-55 2009/08
  •  Medical and psychiatric comorbidity in psychiatric beds in general hospitals: a cross-sectional study in Tokyo. Hatta K, Nakamura H, Usui C, Kobayashi T, Kamijo Y, Hirata T, Awata S, Kishi Y, Arai H, Kurosawa H PSYCHIATRY AND CLINICAL NEUROSCIENCES 63 3 329-335 2009/06
  •  Exploring factors associated with the incidence of sexual harassment of hospital nurses by patients. Hibino Y, Hitomi Y, Kambayashi Y, Nakamura H Journal of Nursing Scholarship 41 2 124-131 2009/06
  •  Perceived stress, severity of asthma, and quality of life in young adults with asthma. Kimura T, Yokoyama A, Kohno N, Nakamura H, Eboshida A Allergology International 58 1 71-79 2009/03
  •  Health impact of disaster-related stress on pregnant women living in the affected area of the Noto Peninsula earthquake in Japan. Hibino Y, Takaki J, Kambayashi Y, Hitomi Y, Sakai A, Sekizuka N, Ogino K, Nakamura H PSYCHIATRY AND CLINICAL NEUROSCIENCES 63 1 107-115 2009/02
  •  Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma. Ooi A, Suzuki S, Nakazawa K, Itakura J, Imoto I, Nakamura H, Dobashi Y ANTICANCER RESEARCH 29 1 19-26 2009/01
  •  Efficient assay for total antioxidant capacity in human plasma using a 96-well microplate. Kambayashi Y, Binh NT, W Asakura H, Hibino Y, Hitomi Y, Nakamura H, Ogino K JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 44 1 46-51 2009/01
  •  Preparation and Characterization of a Polyclonal Antibody against Brominated Protein. Kambayashi Y, Ogino K, Takemoto K, Imagama T, Takigawa T, Kimura S, Hibino Y, Hitomi Y, Nakamura H JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 44 1 95-103 2009/01
  •  Disturbed Homeostasis in Patients with Acute Psychosis. Hatta K, Chie Usui, Nakamura H Curr Psychiatry Rev. 4 4 190-195 2008/11
  •  In vitro toxicity evaluation of diesel exhaust particles on human eosinophilic cell. Hirota R, Akimaru K, Nakamura H. TOXICOLOGY IN VITRO 22 4 988-994 2008/06
  •  Olanzapine orally disintegrating tablet vs. risperidone oral solution in the treatment of acutely agitated psychotic patients. Gen Hosp Psychiatry. Hatta K, Kawabata T, Yoshida K, Hamakawa H, Wakejima T, Furuta K, Nakamura M, Hirata T, Usui C, Nakamura H, Sawa Y GENERAL HOSPITAL PSYCHIATRY 30 4 367-371 2008/07
  •  Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms. Hatta K, Miyakawa K, Ota T, Usui C, Nakamura H, Arai H. JOURNAL OF ECT 23 4 233-235 2007/12
  •  Relationship between mental health of Japanese residents and the quality of medical service. Yoshino S, Sasahara S, Maeno T, Kitaoka-Higashiguchi K, Tomotsune Y, Taniguchi K, Tomita E, Usami K, Haoka T, Nakamura H, Matsuzaki I. J Phys Fit Nutri Immunol. 7 1 3-11 2007/08
  •  Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis. Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Ogino K, Akimaru K, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 142 4 329-334 2007/03
  •  Psychological factors including sense of coherence and some lifestyles are related to General Health Questionnaire-12 (GHQ-12) in elderly workers in Japan. Matsuzaki I, Sagara T, Ohshita Y, Nagase H, Ogino K, Eboshida A, Sasahara S, Nakamura H. Environ Health Prev Med 12 2 71-77 2007/03
  •  Association between Physical Restraint and Drug-Induced Liver Injury. Hatta K, Shibata N, Ota T, Usui C, Ito M, Nakamura H, Arai H. NEUROPSYCHOBIOLOGY 56 4 180-184 2007
  •  Influences of the stress coping ability of supervisors on the stress situation of their subordinates. Tatsukawa H, Sasahara S, Yoshino S, Tomotsune Y, Taniguchi K, Nakamura H, Matsuzaki I. J Phys Fit Nutri Immunol 15 2 82-87 2005/12
  •  What affects the General Health Questionnaire score among former Hansen's Disease patients in leprosarium? J Phys Fit Nutri Immunol 15 2 69-81 2005/12
  •  Psychological well-being and associated factors among elderly Hansen's disease patients in leprosaria. Kataoka M, Nakamura H. Environ Health Prevent Med 10 4 201-207 2005/07
  •  Induction of eosinophil peroxidase and nitrotyrosine formation in a human leukemia cell line, EoL-1. Cell Biochem Funct 22 2 105-112 2004/03
  •  Eradication of epstein-barr virus episome and associated inhibition of infected tumor cell growth by adenovirus vector-mediated transduction of dominant-negative EBNA1. Nasimuzzaman M, Kuroda M, Dohno S, Yamamoto T, Iwatsuki K, Matsuzaki S, Mohammad R, Kumita W, Mizuguchi H, Hayakawa T, Nakamura H, Taguchi T, Wakiguchi H, Imai S. MOLECULAR THERAPY 11 4 578-590 2005/04
  •  Increasing prevalence of Japanese cedar pollinosis: a meta-regression analysis. Kaneko Y, Motohashi Y, Nakamura H, Endo T, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 136 4 365-371 2005/04
  •  A study on the mechanisms of depressive tendency in patients with cedar pollinosis focusing on the sense of coherence (SOC) as a stress-coping skill. Hattori K, Sasahara S, Nakamura H, Ozasa K, Endo T, Imai T, Ide T, Honda Y, Hatta K, Motohashi Y, Eboshida A, Matsuzaki I. J Phys Fit Nutr Immnol 14 3 188-194 2004/12
  •  Physiological involvement of placental endothelin-1 and prostaglandin F2alpha in uteroplacental circulatory disturbance in pregnant rats exposed to heat stress. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 82 4 225-230 2004/04
  •  Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with Japanese cedar pollinosis. Nakamura H, Higashikawa F, Miyagawa K, Nobukuni Y, Endo T, Imai T, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Hatta K, Ogino K, Eboshida A. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 135 1 40-43 2004/09
  •  Higher sense of coherence as a psychological factor responsible for elevated natural killer cell activity in patients with cedar pollinosis. Nakamura H, Matsuzaki I, Sasahara S, Hatta K, Endo T, Imai T, Ozasa K, Motohashi Y, Ogino K, Eboshida A. J Phys Fit Nutri Immunol 14 1 25-32 2004/04
  •  Catalase catalyzes nitrotyrosine formation from sodium azide and hydrogen peroxide Free Radic Res 35 735-747 2001/12
  •  Elevated serum nitric oxide metabolites in hypertensives J Phys Fit Nutri Immunol 11 34-39 2001/12
  •  Plasma VEGF concentration can predict the tumor angiogenic capacity in non-small cell lung cancer Oncol Rep 8 1097-1102 2001/09
  •  Natural killer cell activity and its related psychological factor, sense of coherence in male smokers J Occup Health 43 191-198 2001/07
  •  The association between intravenous haloperidol and prolonged QT interval J Cli Psychopharmacol 21 257-261 2001/06
  •  Mental health of scientific researchers. I. Characteristics of job stress among scientific researchers working at a research park in Japan Int Arch Occup Environ Health 74 199-205 2001/04
  •  Involvement of central, but not placental corticotropin releasing hormone (CRH) in heat stress-induced immunosuppression during pregnancy BRAIN BEHAVIOR AND IMMUNITY 15 43-53 2001/03
  •  Heat produces uteroplacental circulatory disturbance in pregnant rats through action of corticotropin releasing hormone (CRH) PLACENTA 21 510-515 2000/07
  •  Prolonged QT interval in acute psychotic patients PSYCHIATRY RESEARCH 17 279-85 2000/07
  •  Uteroplacental circulatory disturbance in pregnant rats exposed to microwaves through actions of prostaglandin F2α REPRODUCTIVE TOXICOLOGY 14 235-240 2000/05
  •  Prolonged upper airway instability in the parenteral use of benzodiazepine with levomepromazine JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 20 99-101 2000/02
  •  A retrospective study of occular toxocariasis in Japan: correlation with antibody prevalence and ophthalmological findings of patients with uveitis JOURNAL OF HELMINTHOLOGY 73 357-361 1999/12
  •  Association between QOL and its related factors including stress and mother-child relationship in adolescent children Hokuriku J Public Health 25 72-78 1999/11
  •  Hypokalemia and agitation in acute psychotic patients Psychiat Res 86 85-88 1999/04
  •  Laboratory findings in acute schizophrenia: relevance to medical management on emergency admission Gen Hosp Psychiatry 21 220-227 1999/06
  •  Sodium azide inhibits nitric oxide production by rat neutrophils J Phys Fit Nutr Immunol 9 103-108 1999/09
  •  Natural killer (NK) cell activity and NK cell subsets in workers with a tendency of burnout J Psychosom Res 46 569-578 1999/06
  •  The predictive value of benzodiazepine tolerance in persistently aggressive schizophrenia NEUROPSYCHOBIOLOGY 39 0 196-199 1999/05
  •  Central administration of interleukin-1β reduces natural killer cell activity in non-pregnant rats, but not in pregnant rats PSYCHONEUROENDOCRINOLOGY 23 651-659 1998/08
  •  A risk for obstruction of the airways in the parenteral use of levomepromazine with benzodiazepine PHARMACOPSYCHIATRY 31 0 126-130 1998/07
  •  Opioid peptides mediate heat stress-induced immunosuppression during pregnancy Am J Physiol 274 R672-R676 1998/03
  •  Abnormal physiological conditions in acute schizophrenic patients on emergency admission: dehydration, hypokalemia, leukocytosis and elevated serum muscle enzymes Eur Arch Psychiatr Clin Neurosci 248 180-188 1998
  •  Natural killer cell activity reduced by microwave exposure during pregnancy is mediated by opioid systems Environ Res 79 106-113 1998/11
  •  Inhibitory effect of pregnancy on stress-induced immunosuppression through corticotropin releasing hormone (CRH) and dopaminergic systems J Neuroimmunol 75 1-8 1997/05
  •  Effects of exposure to microwaves on cellular immunity and placental steroids in pregnant rats Occup Environ Med 54 676-680 1997/09
  •  Involvement of central neurotensin in thermoregulatory and neuroimmune function in pregnant rats exposed to heat Brain Behav Immun 11 141-152 1997/06

Conference Presentations

Arts and Fieldwork

Patent

Theme to the desired joint research

○Epidemiologic study on microwave effects
○Development of Indicators for Work Stress

Grant-in-Aid for Scientific Research

○「インフルエンザウイルスとスギ花粉T細胞エピトープを用いた新しいリポソームワクチン」(2012-) 
○「腸内細菌叢マイクロバイオームの解析を用いたアレルギーと肥満の新しい予防法の開発」(2013-2015) 
○「インフルエンザウイルスとスギ花粉T細胞エピトープを用いた新しいリポソームワクチン」(2011-) 
○「アレルギー疾患エピジェネティクスにおけるウイルス感染の役割解明とその予防法の開発」(2013-) 
○「アレルギー疾患エピジェネティクスにおけるウイルス感染の役割解明とその予防法の開発」(2012-) 
○「アレルギー疾患エピジェネティクスにおけるウイルス感染の役割解明とその予防法の開発」(2011-) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2011-) 
○「脊髄障害性疼痛症候群の実態の把握と病態の解明に関する研究(難治性疾患克服 研究事業)」(2011-) 
○「慢性の痛み診療の基盤となる情報の集約とより高度な診療のための医療システム構築に関する研究(慢性の痛み対策 研究事業)」(2013-) 
○「難治性疼痛の実態の解明と対応策の開発に関する研究(慢性の痛み対策 研究事業)」(2012-) 
○「難治性疼痛の実態の解明と対応策の開発に関する研究(慢性の痛み対策 研究事業)」(2011-) 
○「成人独自のアナフィラキシーの実態と病態に関する研究(免疫アレルギー疾患等予防・治療 研究事業)」(2011-) 
○「インフルエンザウイルスとスギ花粉T細胞エピトープを用いた新しいリポソームワクチン」(2010-) 
○「RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法」(2010-) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2010-) 
○「脊髄障害性疼痛症候群の実態の把握と病態の解明に関する研究(難治性疾患克服 研究事業)」(2010-) 
○「難治性慢性疼痛の実態と病態の解明に関する研究(障害者対策総合 研究事業)」(2010-) 
○「RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法」(2009-) 
○「重症・難治性喘息の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2009-) 
○「RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法」(2008-) 
○「気管支喘息難治・重症化の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2008-) 
○「気管支喘息難治・重症化の病因・病態の解明に関する研究(免疫アレルギー疾患予防・治療 研究事業)」(2007-) 
○「環境中物質と好酸球関連蛋白遺伝子の相互作用解明によるアレルギー疾患の予防」(2007-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2006-) 
○「環境中物質と好酸球関連蛋白遺伝子の相互作用解明によるアレルギー疾患の予防」(2006-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2005-) 
○「環境中物質と好酸球関連蛋白遺伝子の相互作用解明によるアレルギー疾患の予防」(2005-) 
○「気管支喘息の有病率・罹患率およびQOLに関する全年齢階級別全国調査(免疫アレルギー疾患予防・治療 研究事業)」(2004-) 
○「マイクロ波による子宮胎盤循環及び胎盤機能障害に対する胎児側防御機構の解明」(2002-) 
○「マイクロ波による子宮胎盤循環及び胎盤機能障害に対する胎児側防御機構の解明」(2001-) 
○「マイクロ波超低レベル発生試験解析システムの開発」(2001-) 
○「マイクロ波超低レベル発生試験解析システムの開発」(2000-) 
○「物理的環境ストレスによる胎盤CRH及びオピオイド受容体遺伝子発現とその生理的意義」(2000-) 
○「物理的環境ストレスによる胎盤CRH及びオピオイド受容体遺伝子発現とその生理的意義」(1999-) 
○「マイクロ波の低レベル変調波による妊娠母胎の神経内分泌免疫系への影響」(1998-) 
○「マイクロ波の低レベル変調波による妊娠母胎の神経内分泌免疫系への影響」(1997-) 

Classes (Bachelors)

○Lecture on Life in Campus and Society(2017)
○Introduction to Region-studies(2017)
○Public Health(2017)
○Lecture on Life in Campus and Society(2016)
○Public Health(2016)
○Public Health(2016)
○Introduction to Region-studies(2016)

Classes (Graduate Schools)

○Seminar of Medical Statistics(2017)
○Environmental Health and Preventive Medicine(2017)
○Environmental Health and Preventive Medicine(2017)
○Environment and Health -Introductory(2017)
○Seminar of Medical Statistics(2017)
○Environment and Health -Introductory(2017)
○Environment and Health -Introductory(2017)
○Itemized Lectures on Medical Statictics(2017)
○Itemized Lectures on Medical Statictics(2017)
○Environmental Health and Preventive Medicine(2017)
○Environment and Heredity(2017)
○Medical Statistics and Epidemiology(2017)
○Environment and Health(2017)
○Itemized Lectures on Medical Statictics(2017)
○Seminar of Medical Statistics(2017)
○Preventive Medicine(2017)
○Bio-Ethics(2017)
○Preventive Medicine(2017)
○Environment and Health(2017)
○Hygiene and Public Health(2017)
○Environment and Health -Introductory(2016)
○Introduction to Basic Medical Science(2016)
○Environmental Health and Preventive Medicine(2016)
○Environmental Health and Preventive Medicine(2016)
○Environment and Health -Introductory(2016)
○Itemized Lectures on Medical Statictics(2016)
○Seminar of Medical Statistics(2016)
○Seminar of Medical Statistics(2016)
○Environmental Health and Preventive Medicine(2016)
○Preventive Medicine(2016)
○Environment and Health(2016)
○Bio-Ethics・Research-Ethics(2016)
○Environment and Health -Introductory(2016)
○Seminar of Medical Statistics(2016)
○Medical Statistics and Epidemiology(2016)
○Environment and Health -Introductory(2016)
○Itemized Lectures on Medical Statictics(2016)
○Itemized Lectures on Medical Statictics(2016)
○Environment and Health(2016)
○Hygiene and Public Health(2016)
○Preventive Medicine(2016)
○Environment and Heredity(2016)

International Project

International Students

Lecture themes

○Prevention of Allergy

Others (Social Activities)

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