Associate Professor SHINMYO, Yohei
Faculty, Affiliation
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences
College and School Educational Field
Laboratory
Academic Background
Career
Kumamoto University(2005/04-2006/03)
Kumamoto University(2006/04-2007/03)
Kumamoto University(2007/04-2014/03)
Kanazawa University(2014/04-)
Year & Month of Birth
1978/03
Academic Society
Award
Specialities
Neurophysiology/General neuroscience
Speciality Keywords
Research Themes
Books
- Shinmyo Y., Masuda K., Hoshiba Y., Ebisu H. and Kawasaki H. Brain Evolution by Design Springer Publishers 2017/01/04
Papers
- Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice Naofumi Ito , M Asrafuzzaman Riyadh, Shah Adil Ishtiyaq Ahmad, Satoko Hattori , Yonehiro Kanemura , Hiroshi Kiyonari , Takaya Abe , Yasuhide Furuta, Yohei Shinmyo , Naoko Kaneko , Yuki Hirota, Giuseppe Lupo , Jun Hatakeyama , Felemban Athary Abdulhaleem M, Mohammad Badrul Anam , Masahiro Yamaguchi, Toru Takeo , Hirohide Takebayashi, Minoru Takebayashi, Yuichi Oike, Naomi Nakagata , Kenji Shimamura, Michael J Holtzman, Yoshiko Takahashi, Francois Guillemot, Tsuyoshi Miyakawa, Kazunobu Sawamoto, Kunimasa Ohta. Sci Transl Med 13(587):eaay7896. 2021/03
- The expression of aristaless-related homeobox in neural progenitors of gyrencephalic carnivore ferrets Hiroki Maeyama , Yohei Shinmyo , Hiroshi Kawasaki. Biochem Biophys Rep 26:100970. 2021/03
- Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation Toshihide Hamabe-Horiike , Kanji Kawasaki , Masataka Sakashita , Chihiro Ishizu , Tomokazu Yoshizaki , Shin-Ichi Harada, Keiko Ogawa-Ochiai, Yohei Shinmyo, Hiroshi Kawasaki. Scientific Reports 11(1):4864. 2021/03
- A novel third mesh-like myometrial layer connects the longitudinal and circular muscle fibers -A potential stratum to coordinate uterine contractions Kyosuke Kagami , Masanori Ono , Takashi Iizuka, Takeo Matsumoto , Takashi Hosono , Naomi Sekizuka-Kagami , Yohei Shinmyo, Hiroshi Kawasaki, Hiroshi Fujiwara. Scientific Reports 10(1):8274. 2020/05
- A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain Naoyuki Matsumoto, Satoshi Tanaka, Toshihide Horiike, Yohei Shinmyo, Hiroshi Kawasaki. eLife 9:e54873. 2020/04
- Draxin-mediated Regulation of Granule Cell Progenitor Differentiation in the Postnatal Hippocampal Dentate Gyrus. Tawarayama H, Yamada H, Amin R, Morita-Fujimura Y, Cooper HM, Shinmyo Y, Tanaka H, Ikawa S. Neuroscience 431 184-192 2020/04
- The origin and development of subcortical U-fibers in gyrencephalic ferrets. Yoshino M, Saito K, Kawasaki K, Horiike T, Shinmyo Y, Kawasaki H. Mol Brain 13 1 37 2020/03
- Characterization of the Inner and Outer Fiber Layers in the Developing Cerebral Cortex of Gyrencephalic Ferrets. Saito K, Mizuguchi K, Horiike T, Dinh Duong TA, Shinmyo Y, Kawasaki H. Cereb Cortex 29 10 4303-4311 2019/09
- FGF Signaling Directs the Cell Fate Switch from Neurons to Astrocytes in the Developing Mouse Cerebral Cortex. Dinh Duong TA, Hoshiba Y, Saito K, Kawasaki K, Ichikawa Y, Matsumoto N, Shinmyo Y, Kawasaki H. J Neurosci. 39 31 6081-6094 2019/07
- Three-dimensional evaluation of murine ovarian follicles using a modified CUBIC tissue clearing method Kagami K., Shinmyo Y., Ono M., Kawasaki H. and Fujiwara H. Reproductive Biology and Endocrinology 16 1 72 2018/08
- The chemorepellent draxin is involved in hippocampal mossy fiber projection Tawarayama H., Yamada H., Shinmyo Y., Tanaka H. and Ikawa S. Biochemical and Biophysical Research Communications 500 2 217-223 2018/06
- Distribution and morphological features of microglia in the developing cerebral cortex of gyrencephalic mammals Mizuguchi K., Horiike T., Matsumoto N., Ichikawa Y., Shinmyo Y. and Kawasaki H. Neurochemical Research 43 5 1075-1085 2018/05
- Expression of Draxin in lung carcinomas Sato Y., Matsuo A., Kudoh S., Fang L., Hasegawa K., Shinmyo Y., and Ito T. Acta Histochemica et Cytochemica 1 1 53-62 2018/02
- Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Tawarayama H., Yamada H., Amin R., Morita-Fujimura Y., Cooper H.M., Shinmyo Y., Kawata M., Ikawa S. and Tanaka H. Scientific Reports 8 1 840 2018/01/16
- Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain Matsumoto N., Shinmyo Y., Ichikawa Y. and Kawasaki H. eLife 6 e29285 2017/11/14
- Folding of the cerebral cortex requires Cdk5 in upper-layer neurons in gyrencephalic mammals Shinmyo Y., Terashita Y., Dinh Duong T. A., Horiike T., Kawasumi M., Hosomichi K., Tajima A. and Kawasaki H. Cell Reports 20 9 2131-2143 2017/08/29
- Three-dimensional visualization of intrauterine conceptus through the uterine wall by tissue clearing method. Kagami K., Shinmyo Y., Ono M., Kawasaki H. and Fujiwara H. Scientific Reports 7 1 5964 2017/07/20
- CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporation. Shinmyo Y., Kawasaki H. Current Protocols in Neuroscience 79 3.32 1-11 2017/04
- Pathophysiological analyses of periventricular nodular heterotopia using gyrencephalic mammals. Matsumoto N., Hoshiba Y., Morita K., Uda N., Hirota M., Minamikawa M., Ebisu H., Shinmyo Y. and Kawasaki H. Human Molecular Genetics 26 6 1173-1181 2017/01
- Inhibitory effects of draxin on axonal outgrowth and migration of precerebellar neurons Riyadh M. A., Shinmyo Y., Ohta K. and Tanaka H Biochemical and Biophysical Research Communications 449 1 169-174 2014/06/20
- An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals Toda T., Shinmyo Y., Dinh Duong T. A., Masuda K., and Kawasaki H Scientific Reports 6 29578 2016/07/12
- Roles of an axon guidance protein Draxin in neural circuit formation 125 2 55-59 2016/06
- CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporation Shinmyo Y., Tanaka S., Tsunoda S., Hosomichi K., Tajima A. and Kawasaki H Scientific Reports 6 20611 2016/02/09
- Pathophysiological analyses of cortical malformation using gyrencephalic mammals. Masuda K., Toda T., Shinmyo Y., Ebisu H., Hoshiba Y., Wakimoto M., Ichikawa Y. and Kawasaki H. Scientific Reports 5 15370 2015/10/20
- Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Shinmyo Y., Riyadh M. A., Ahmed G., Naser I. B., Hossain M., Takebayashi H., Kawasaki H., Ohta K. and Tanaka H. Nature Communications 6 10232 2015/12/14
Conference Presentations
Others
Arts and Fieldwork
Patent
Theme to the desired joint research
Grant-in-Aid for Scientific Research
○2022「軸索ガイダンスを切り口とした脳回形成機構の解明」(2020-2022)
○「フェレットの大脳皮質形成機構の解明とその破綻による疾患病態の解析」(2018-2019)
○「軸索ガイダンスに着目した大脳皮質形成機構の解明」(2016-2018)
○「大脳皮質特異的なノックアウト動物作成法の開発」(2015-2016)
○「糖鎖による軸索ガイダンス分子draxinの機能制御機構の解明」(2014-2015)
Competitive research funding,Contribution
Collaborative research,Consignment study
Classes (Bachelors)
○Neurophysiology(2020)
○Basic Health Science(2020)
○Neurophysiology(2019)
Classes (Graduate Schools)
○General Neurogenetics(2021)
○General Neurogenetics(2020)
○General Neurogenetics(2020)
○Frontier Life Science(2020)
○The Human Body in Health and Disease Curriculum 3(2020)
○General Neurogenetics(2019)
○Frontier Life Science(2019)
○General Neurogenetics(2019)
○General Neurogenetics(2018)
○General Neurogenetics(2018)
○Introduction to Medical Science(2018)
○Frontier Life Science(2018)
○Frontier Life Science(2017)
○General Neurogenetics(2017)
○General Neurogenetics(2017)
○Frontier Life Science(2016)
○General Neurogenetics(2016)
○General Neurogenetics(2016)